Switching from Retatrutide to Tirzepatide — Dose conversion advice?
-
@BeeKind I honestly don't know why everyone is so quick to jump on Reta. Tirz and Sema have been on the market for years and aside from GI upset, they are very well tolerated. Reta has a ton of side effects and hasn't even passed phase 3
All GLPs have side effects. Including Tirz. When I needed to lose 150 pounds Tirz was great. Its a sledge hammer. When I wanted to lose 30 pounds of fat while being able to hit a calorie target and build muscle Reta is King. Visceral fat reduction is epic. Its a scalpel. BTW I've had less side effects on Reta than I had on Tirz. But this was do to better education and finding the lowest effective dose.
@Mydogdaryl423 I'm a weird outlier who felt zero appetite reduction even at 8mg per week of Tirz. On 6mg of Reta, I still have to force myself to eat.
-
@BeeKind Reta is great, I've used it for 5 months now and it was the best decision I've taken. I'm looking to switch just because I want to sleep better
@RagnatLothbrok I've been using Reta for 4 months now, lost 40lbs so far and it's been great in that way, but my sleep was already a struggle before and now sleeping is impossible. I also don't have consistent "food noise reduction". I also have side effects some weeks and others it's like I didn't pin at all. I just want to feel mostly decent most of the time.
-
All of these experiences being shared illustrate perfectly biological variability. I have zero issues with my sleep from Reta and my food noise is dissipated. Def not gone the way it was with Tirz. All great tools and learning to use them to maximize your current goals is the joy of research.
-
All of these experiences being shared illustrate perfectly biological variability. I have zero issues with my sleep from Reta and my food noise is dissipated. Def not gone the way it was with Tirz. All great tools and learning to use them to maximize your current goals is the joy of research.
@Mydogdaryl423 Could be related to where people get their Reta from. Some COA's are far more accurate than others. I saw a COA on Telegram from I think Trustpoint that was like 91pct and the Freedom COA on the website was 99.7pct. That will certainly affect potency, and who knows what else could be mixed in there. Some of these labs can't be trusted right now, and that could be one of the reasons people see different results or have different experiences.
If I were starting out today, I would start by buying from the most reputable vendor with rock-solid testing from a rock-solid lab, then at least I have something to compare to if I take a chance on another vendor or go grey.
I have had two different people hit me up saying they were having a bad experience on Reta I asked where they got it and said Do yourself a favor before you switch or quit altogether: order from X. It made all the difference.
-
I switched the other way a month ago. Went from what would had been a 7.5 Tirz to .5 Reta which was WAY not enough. Titrated up to my current 2mg and am back on track so take that for what it is worth.
-
Active muscle is what burns the most calories ( most ATP). It is a great part the metabolic chain. Not eating enough food over a long period forces the body into starvation mode. The *side effects are the break down muscle and fat for energy, slows the metabolism, and causes severe harm to the bones, heart, brain, and hormonal systems. You guys need to eat. Well need to learn how to eat. Reta allows you to do just that and still loose weight. With reta alone you'll loose a ld a week. Tune up your diet you'll loose more. Start exercising even more and you'll be preserving muscle. You need to titrate/dail your Reta right until you find the sweet spot. You need to eat people. Just YouTube glp friendly foods. Just be careful with the meats today. For all we know we are being fed all them wild horses they rounded up recently.
2M
-
Active muscle is what burns the most calories ( most ATP). It is a great part the metabolic chain. Not eating enough food over a long period forces the body into starvation mode. The *side effects are the break down muscle and fat for energy, slows the metabolism, and causes severe harm to the bones, heart, brain, and hormonal systems. You guys need to eat. Well need to learn how to eat. Reta allows you to do just that and still loose weight. With reta alone you'll loose a ld a week. Tune up your diet you'll loose more. Start exercising even more and you'll be preserving muscle. You need to titrate/dail your Reta right until you find the sweet spot. You need to eat people. Just YouTube glp friendly foods. Just be careful with the meats today. For all we know we are being fed all them wild horses they rounded up recently.
-
Thats the key to Reta. Turns out the protein content is sick. BTW if this were true half you sickos would be in a TG chat tonight looking for a GB.
-
You need to eat people.
I just want to point out the importance of punctuation. Made me laugh. That might be why I'm having issues, I'm not eating people.
-
Stop it....
-
@BeeKind good one. Haha. Hey a few months ago I came across a video of some DNA testing ground beef. Guess what they claim it came back as?
@EXTROPIAN I believe it. I haven't seen any new cemeteries in my lifetime, have you?
Soilent Green
-
I'm currently planning to switch my protocol from Retatrutide to Tirzepatide and could use some advice on equivalent dosing. I'm currently on 2mg per week, what would that be for Tirz?
I'm currently planning to switch my protocol from Retatrutide to Tirzepatide and could use some advice on equivalent dosing. I'm currently on 2mg per week, what would that be for Tirz?
What others are saying about Tirz dosage is essentially correct. You will not get the glucagon pathway but of course, you will get the other 2; GLP-1 & GIP.
I've heard from a couple of different people on this and other forums that Tirz and Reta didn't quite get them to goal weight and is becoming a struggle. Well, yeah; it's much harder to drop the pounds as your body diminishes in fat content. The poster above who said exercise is key is right as rain; it doesn't have to be hard exercise either. I use resistance bands and love them.
If I knew before I started on weight loss peps what I know now, I would have worked the peps very differently and left the GIP component for last. Tirz is not your only alternative. Remember that you have Cagri and Survo you can work with, neither of which are GIP agonists.
-
I always see people say Tirz has better appetite suppression but at the same time people talk about using 2-4mg of Reta. What's the appetite suppression of 10mg of reta like? It wouldn't do so well in the trials if it wasn't suppressing appetite. People would out eat the glucagon effect of the weight loss. Of course 2-4mg of reta isn't going to suppress appetite like 12-15mg of Tirz.
-
It does provide appetite suppression but they are designed differently. If you look at the curve of dosage to side effects of Reta above 10 the gain is tiny but the side effects go way up.
-
Dr Jones DC has Reta down and simply explains it. He has quite a few videos covering Reta. He covers Tirz as well. Subscribe he is good. I just happen to agree with him from experience. Reta is not perfect but we figured out how it can be dialed to make it beneficial to the individual.
https://youtu.be/Urx7b7XxU4A?is=f9nir97G9Paq9KG9 -
Dr. Kevin Joseph, on the other hand, lost over 150#, pulled back and started micro-dosing, got too slack and gained 20# back before he caught himself and started peps and exercise again. He is a big fan of Reta too, as well as the others. He and I have debated on a few occasions and he doesn't mind. Here's one that's interesting. He surprised me with this one, but will pass, for now. (Too much!)
-
@lucytrarnoldvg this is another scam/spam supplier partnership bs
Hello! It looks like you're interested in this conversation, but you don't have an account yet.
Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.
With your input, this post could be even better 💗
Register Login