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  3. MOTS - C who shouldn’t take it? Side effects / potential dangers?
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MOTS - C who shouldn’t take it? Side effects / potential dangers?

Scheduled Pinned Locked Moved Peptide Discussion
mots-c
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  • J JtCjEfF

    I’ve seen one article cautioning it’s use for anyone with MTHFR and/or issue with their methylation cycle.

    E Offline
    E Offline
    Eleanor
    wrote last edited by Eleanor
    #16

    @JtCjEfF said:

    I’ve seen one article cautioning it’s use for anyone with MTHFR and/or issue with their methylation cycle.

    I have MTHFR and take 1mg/d with NAD+buff. I do take extra B with it and only problem is it keeps me from sleeping well. After this vial is done, the remainder goes into the freezer.

    Mixes very well with NaCl BAC.

    Proud to be on a gubmint watch list

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    • S Stevepep

      @Shaqdiesel I am not sure if it is ok for 5 Amino. It is for SS31 and MOTSC and I use it for buffered NAD as well

      S Offline
      S Offline
      Shaqdiesel
      wrote last edited by
      #17

      @Stevepep My HVY 5Amino came premixed so I am only using on the MOTS and SS. I was just mentioning I do get a minor ISR with the 5Amino.

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      • S Shaqdiesel

        @Stevepep My HVY 5Amino came premixed so I am only using on the MOTS and SS. I was just mentioning I do get a minor ISR with the 5Amino.

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        S Offline
        Stevepep
        wrote last edited by
        #18

        @Shaqdiesel gotcha I haven't tried 5 amino

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        • pep_researcherP Offline
          pep_researcherP Offline
          pep_researcher
          wrote last edited by pep_researcher
          #19

          🐀 got two freaking kits because of the rave reviews about mitochondrial research and all. 🐀 felt nothing different.

          Rat had one serious ISR that lasted a week when it tried on the low fatty portion of thigh which went IM and then it was horrible. Had to take some Benadryl to alleviate the intense itch.

          Rat switched back to fatty site and now just been depleting the stock to get done with it.

          Same experience with SS-31 and NAD precursors. Money down the drain for experiments with no meaningful outcomes.

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          • S Stevepep

            @Randy it’s the weirdest peptide there is no in between it either works great or you have a nasty reaction.

            pep_researcherP Offline
            pep_researcherP Offline
            pep_researcher
            wrote last edited by
            #20

            @Stevepep Third category of 🐀 who just feel meh and feel like money, BAC, noodles, wipes down the drain because of no meaningful research outcome.

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            • pep_researcherP Offline
              pep_researcherP Offline
              pep_researcher
              wrote last edited by
              #21

              FWIW, the bump and itch can alleviate a lot if research site has enough pinch of fat and you apply cold pack immediately after pinning MOTS-C.

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              • mmpM mmp

                @Stevepep

                @Randy

                Have you tried it on your rats?

                RandyR Offline
                RandyR Offline
                Randy
                wrote last edited by
                #22

                @mmp yep. the epi pen in my fridge was looking awfully sexy at the time.

                "If it doesnt come in a needle. It doesn't work"

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                • quicksilver80Q Offline
                  quicksilver80Q Offline
                  quicksilver80
                  wrote last edited by
                  #23

                  Took it for a few months and took a 2 week break for a trip. Even with maybe 25 percent left of a vial im probably not restarting just based on the fear of stopping and restarting. The weight loss from it wasnt worth the gamble. It wasn't significant for me. Could do slu915, atx304, aicar, or even bam15 and not have to worry.

                  pep_researcherP 1 Reply Last reply
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                  • pep_researcherP pep_researcher

                    🐀 got two freaking kits because of the rave reviews about mitochondrial research and all. 🐀 felt nothing different.

                    Rat had one serious ISR that lasted a week when it tried on the low fatty portion of thigh which went IM and then it was horrible. Had to take some Benadryl to alleviate the intense itch.

                    Rat switched back to fatty site and now just been depleting the stock to get done with it.

                    Same experience with SS-31 and NAD precursors. Money down the drain for experiments with no meaningful outcomes.

                    O Offline
                    O Offline
                    ogsteve
                    wrote last edited by
                    #24

                    @pep_researcher

                    I get almost nothing from motsc at 4-5mg. Still experimenting tho.

                    As for ss-31 it really only shines at the 20mg/day level. Below 10mg is a waste of time and money except for the titrate up to 10mg.

                    S S M 3 Replies Last reply
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                    • O ogsteve

                      @pep_researcher

                      I get almost nothing from motsc at 4-5mg. Still experimenting tho.

                      As for ss-31 it really only shines at the 20mg/day level. Below 10mg is a waste of time and money except for the titrate up to 10mg.

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                      Stevepep
                      wrote last edited by
                      #25

                      @ogsteve this is also different for everyone it depends on the condition of the mitochondria

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                      • O ogsteve

                        @pep_researcher

                        I get almost nothing from motsc at 4-5mg. Still experimenting tho.

                        As for ss-31 it really only shines at the 20mg/day level. Below 10mg is a waste of time and money except for the titrate up to 10mg.

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                        S Offline
                        Shaqdiesel
                        wrote last edited by
                        #26

                        @ogsteve I can't wait to do my high mg protocol. 4mgs is all I've done for roughly 6 weeks or so. I have more 50mg kits on order so I can blitz high mgs to see what I get out of it.

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                        • O ogsteve

                          @pep_researcher

                          I get almost nothing from motsc at 4-5mg. Still experimenting tho.

                          As for ss-31 it really only shines at the 20mg/day level. Below 10mg is a waste of time and money except for the titrate up to 10mg.

                          M Offline
                          M Offline
                          Mocha
                          wrote last edited by
                          #27

                          @ogsteve I'm currently doing 4mg/daily of SS-31 and I'm not noticing anything. What are you feeling at 20mg? Is it more energy and endurance? Is it that noticable?

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                          • quicksilver80Q quicksilver80

                            Took it for a few months and took a 2 week break for a trip. Even with maybe 25 percent left of a vial im probably not restarting just based on the fear of stopping and restarting. The weight loss from it wasnt worth the gamble. It wasn't significant for me. Could do slu915, atx304, aicar, or even bam15 and not have to worry.

                            pep_researcherP Offline
                            pep_researcherP Offline
                            pep_researcher
                            wrote last edited by pep_researcher
                            #28

                            @quicksilver80 said:

                            The weight loss from it wasnt worth the gamble

                            Did your 🐀 actually see any weight loss from MOTS-C? Curious.

                            MOTS-C tried alone or with GLP was meh for my 🐀

                            What worked to break the stall for 🐀: Reta, Tesa, Wolverine, KPV, TA-1 (MOTS-C is there but doesn't deserve any credit).... AND paying a shit load of money to a special nutritionist (not through insurance) to tighten screws in rat's food.

                            FWIW 🐀 was not obese to begin with, but wanted to fix blood work.

                            quicksilver80Q 1 Reply Last reply
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                            • pep_researcherP pep_researcher

                              @quicksilver80 said:

                              The weight loss from it wasnt worth the gamble

                              Did your 🐀 actually see any weight loss from MOTS-C? Curious.

                              MOTS-C tried alone or with GLP was meh for my 🐀

                              What worked to break the stall for 🐀: Reta, Tesa, Wolverine, KPV, TA-1 (MOTS-C is there but doesn't deserve any credit).... AND paying a shit load of money to a special nutritionist (not through insurance) to tighten screws in rat's food.

                              FWIW 🐀 was not obese to begin with, but wanted to fix blood work.

                              quicksilver80Q Offline
                              quicksilver80Q Offline
                              quicksilver80
                              wrote last edited by
                              #29

                              pep_researcher was running tesa reta and mots. Mots just gave me flushing feelings getting up thats about it. Lost more weight eating normally on the trip and coming home. So idk. Also know it was legit. And i was running the pc dosing schedule.

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                              • M Mocha

                                @ogsteve I'm currently doing 4mg/daily of SS-31 and I'm not noticing anything. What are you feeling at 20mg? Is it more energy and endurance? Is it that noticable?

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                                ogsteve
                                wrote last edited by ogsteve
                                #30

                                @Mocha sustained energy throughout the day. A nice morning boost and positive attitude that persists. It’s not like caffeine it’s just like you are having a great day.

                                Try bumping to 10-11 over the next three days and see what you feel. If you already went thru the “feeling slow and dragging ass” phase initially you might get that again as you move up. If you do just hold and wait the 4 days for it to pass then move onward. You’ll feel it when you get your dose.

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                                • S Stevepep

                                  @mmp said:

                                  @Stevepep

                                  @Randy

                                  Have you tried it on your rats?

                                  Yes it worked fine for me but it’s different for everyone. I just cycled off for a month and liked it a lot. I titrated up to 6mg 3x per week for 6 weeks. I have seen people have no reaction when they start and wake up with red blotches all over due to a histamine reaction. It builds up in your body over time. I was getting an itchy red area but then I switched to Hospira NACL Bac and it stopped. That’s just me though. We all react differently. So go slow

                                  M Offline
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                                  maryshafer
                                  wrote last edited by
                                  #31

                                  @Stevepep what is your source for the Hospira NACL? I have been pinning MOTS-C (cycling) for a year, but always get the itchy welts that last days. Sometimes 4-5 days, but then go away. Love the workouts with it on board. Just would like to eliminate the "itchy butt" as we call it here at my lab. lol Running 4mg 3x per week. My spouse had to quick after second full cycle because she had sudden welts/blisters all over torso and itchy roof of mouth. So stopped that after second time. Not taking chances.

                                  S 1 Reply Last reply
                                  0
                                  • M maryshafer

                                    @Stevepep what is your source for the Hospira NACL? I have been pinning MOTS-C (cycling) for a year, but always get the itchy welts that last days. Sometimes 4-5 days, but then go away. Love the workouts with it on board. Just would like to eliminate the "itchy butt" as we call it here at my lab. lol Running 4mg 3x per week. My spouse had to quick after second full cycle because she had sudden welts/blisters all over torso and itchy roof of mouth. So stopped that after second time. Not taking chances.

                                    S Offline
                                    S Offline
                                    Stevepep
                                    wrote last edited by Stevepep
                                    #32

                                    @maryshafer for singles try peptidetest.com for a case Medex a case is only $100 unless they raised the price

                                    1 Reply Last reply
                                    0
                                    • documentswitchD Offline
                                      documentswitchD Offline
                                      documentswitch
                                      wrote last edited by
                                      #33

                                      This shit gave me extreme fatigue and brain fog. I've never felt this type of depletion before, it was horrible, it was like it cause mitochondria dysfunction. I couldn't even read a sentence because I didn't have the energy to.

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