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  • E

    This is at least the 2nd time this has happened with a vendor. I will not send any of them my DL info. Sent them a refusal note on the grounds that I already had an account with them and they sent the order through. (Other than that, I like their products.)

    I hope this doesn't become a habit with vendors.


    I'm glad they still processed your order. I would definitely cancel if they required it.
  • E

    On another thread here was a discussion of TB4 and BPC157, 1 to 1 ratio in premixed formulas not being accurate with regard to the individual dosages of the two. I agree with this assessment and since I cannot afford to dose kitty individually, I'm going to try Cartalax first and see if it resolves any of the joint and other tissue pain she has. As we all know, the cost of peptides can be prohibitive, at least for us.

    Any comments/information is welcomed. Wish cat the best. She's old and hurting.
    🙀


    I've been running klow, cartalax, Ara for nerve damage, and local bpc for a couple of months. My numerous surgery sites are feeling much better.
  • M

    This is a vendor review submitted by StevenKing on PeptideCritic.com.

    Rating: ⭐ (1/5)


    Review

    I completely agree with Chad here, something is definitely off with this vendor. I’m into my fourth week on their batch, and honestly, it’s been a total letdown. Not only am I getting zero noticeable results from my usual dose, but I’ve also suddenly come down with a brutal headache and stomach pain. There’s a chance I just caught a bug from someone who was sick around me, but the timing is just too sketchy to ignore. When you get none of the actual benefits but all of these random, miserable side effects, it really makes you question the purity of what they're shipping out. Just like Chad said, the difference between a solid vendor and this one is night and day. On another note, my MOT-C effects seems fine.


    🛒 Shop Glacier Aminos

    📖 Read the full review: Something Off

    Discuss this review, share your own experiences, or ask questions about the vendor.

    Please keep discussions respectful and factual.


  • RandyR

    For research use only. Not medical advice.

    The goal:

    Tirzepatide = GLP-1 + GIP
    Survodutide or Mazdutide = GLP-1 + Glucagon
    → Combined effect = GLP-1 + GIP + Glucagon, i.e., a retatrutide-like profile.

    Because both second agents have a glucagon hit, titration must be slower than usual to avoid nausea, low appetite floor, or excessive gastric slowing.

    Why do this?

    1. You stockpiled too much tirz.
    2. Break a stall.
    3. Reta itch/allodynia or other intolerable side effects when researching reta.

    1. Tirzepatide + Survodutide

    Survodutide has a stronger glucagon hit than mazdutide. This is the more potent combination.

    Weekly Titration Schedule

    Weeks 1–4

    Tirzepatide: 2.5 mg weekly

    Survodutide: 0.3 mg weekly
    Purpose: Establish baseline tolerability. Survo kicks hard early.

    Weeks 5–8

    Tirzepatide: 5 mg weekly

    Survodutide: 0.6 mg weekly
    Notes: Appetite suppression becomes extremely strong for many subjects here.

    Weeks 9–12

    Tirzepatide: 7.5 mg weekly

    Survodutide: 1.0 mg weekly

    This is the sweet spot for most research models. Strong “reta-like” effect emerges.

    Week 13+ Maintenance

    Two viable approaches:

    Standard Maintenance

    Tirzepatide: 7.5–10 mg

    Survodutide: 1.0–1.5 mg

    High-End (Aggressive) Maintenance

    Tirzepatide: 10–12.5 mg

    Survodutide: 1.5–2.0 mg

    Only for researchers replicating the high-end metabolic punch of retatrutide.

    Notes

    Survodutide plus tirz amplifies appetite suppression so hard that most people do not need high tirz dosing.

    Escalate slowly — both compounds slow gastric emptying.

    This combo is more GC-heavy than mazdutide, so itch issues are less common compared to retatrutide, but GI load is higher.

    1. Tirzepatide + Mazdutide (Ghetto Reta v2 — Milder, Cleaner)

    Mazdutide has a slightly softer glucagon hit and a less aggressive appetite cliff.
    This stack is smoother and usually more tolerable.

    Tirzepatide + Mazdutide

    Weeks 1–4

    Tirzepatide: 2.5 mg weekly

    Mazdutide: 2 mg weekly

    Weeks 5–8

    Tirzepatide: 5 mg weekly

    Mazdutide: 4 mg weekly

    Weeks 9–12

    Tirzepatide: 7.5 mg weekly

    Mazdutide: 6 mg weekly

    This combo mimics a “mid-dose retatrutide” effect without the itch or violent GI spike.

    Week 13+ Maintenance

    Tirzepatide: 7.5–10 mg

    Mazdutide: 6–8 mg

    High-End (Not common)

    Tirzepatide: 10–12.5 mg

    Mazdutide: 8–10 mg

    Notes

    Mazdutide is smoother but still synergistic with tirz.

    Appetite suppression is strong but less harsh than survo stacks.

    GI load increases if escalated too fast — keep 4-week steps.


    read more →
    I posted on a discord server that my food nose was back since I started survo. Tirz had me completely dead to appetite. Some "expert" jumped on and explained the mechanisms of why survo would not cause hunger/food noise. Well, I know what I have experienced. But luckily it has died down and only lasts the day I take the survo. But I've been eating keto/carnivore ish most of the time so sugar cravings aren't a thing for me. I'd rather have a large pepperoni pizza. I am now down 78 pounds since January so I'm sticking with this combo.
  • M

    My rat name Extropy has been researching for 5mo with great results. From metabolic reset, mitochondria optimizing, mental health, longevity, immune and yes she went all in. She is filtering all the peps into pen cartridges as suggested here. In one sitting Extropy has been able to push a set of 2-4 cartridges through one 33Gx4mm pin tip. After she finish the pen tip it gets discarted. She hasn't had any issues. Anyone doing the same or?


    read more →
    @Commander Agree. One the topic of antibiotics I always been stocked way before I dabbled with peps. You can find them at your local livestock supply stores here. If you know what you're looking for you'll find it without prescription. I got most from Mex. Thanks
  • WesEqualshXcW

    This is a vendor review submitted by WesEqualshXc on PeptideCritic.com.

    Rating: ⭐⭐⭐⭐⭐ (5/5)


    Review

    Have you ever developed a crush on somebody and couldn't help but want to text them? Yeah, that happened to me with this company. After I received my first order, which shipped pretty quickly, I found myself going back to their website several times debating whether or not I should spend the money to buy more stuff. For my money, they strike a perfect balance between price, packaging, convenience, and detailed COAs. I’ll probably continue to buy from these guys.


    🛒 Shop Crush Research

    📖 Read the full review: I’m developing a massive Crush!

    Discuss this review, share your own experiences, or ask questions about the vendor.

    Please keep discussions respectful and factual.


    @SkepticJen ️ ... yeah cuz my Chihuahua needs some stuff and my ADHD isnt gonna hold out much longer!
  • RandyR

    Aavant just announced another restock. They are usa based, lio in the states (allegedly), ships from ohio and sells out quick. These prices are lower than grey (unless buying 100 kits).

    IsQ127q_d.webp

    Join here https://t.me/+zyQ_V2wK4vY1NDg5

    Test groups always form and its a wonderful community.

    These sell out FAST.


    @Newenough It was probably a spoof account, but if you DO want the real Aavant's Maz or Survo, kits of 10 seem to still be available through the bot for $75 +$12ish shipping, which is pretty cheap for domestic
  • S

    What is the suggested protocol. Just got confused by other posts. @randy you love it please chime in. I am titrating starting at 1mg up to 5 for the last 5 days for 20 days total. Just started


    @Stevepep search function is very useful here. https://community.peptidecritic.com/post/5042 FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.
  • M

    My rat Extropy has been using V2 pens for 3mo now and I'm about to upgrade. When she pinch, pin and pray. Extropy lets it sit in her for 10-20 seconds before pulling out slowly. She still notices a drop of peps on the pin tip. She is now using 33G x 4mm, but also it did the same with a 32G. There is a few MCGs lost in every pin. Lately she has been unscrewing the pen reservoir to not lose any more peps. Yes she did use to remove the pen tip but by the time you cap it and unscrew the mcgs add up. It a decent little drop. I didn't mind it, considering it is clear there isn't a backwash into the cartridge. Time to upgrade, "this is the way"...? Follistatin-344 and tesa are not cheap. Please advise.


    @martinmarin That's just part of it. My pens do it too. There's always going to be some loss to be expected. I lose 2 units before every pin priming the pen needle to make sure I get my correct dose.
  • N

    Well I just had an unpleasant experience. I just wasted a half a vial of NAD+. Upon filling some pen cartridges I had the bottom plug pop out the bottom of not one, but two cartridges (spilling all of the energy juice into oblivion). I was using a 31 gauge breather needle and a 31 gauge needle on the end of the .2-13mm filter. I've done it this way before with no issues. I didn't think I was pushing too hard or fast on the plunger but I guess I could have. I changed the breather needle on the next two cartridges and everything went as planned. Could it have been a bad breather needle? 31 gauge needles are too small (for breather or filter)? Or was I simply pushing too fast and didn't realize it?

    What's your theory as to what the problem may have been. I lost half of my 10mL vial due to this mistake, so I darn sure want to learn from it.


    @SwollStreetBets I like that I’ve got a couple of those reconstitution stations - they look shit hot but I never use them.
  • N

    I hate to be an enabler for all the FOMO and hoarder peeps out there, but I thought it might be a good idea to have a centralized location for all of the July 4th sales. This wouldn't necessarily be an endorsement for any particular vendor or a review, but rather an FYI for what's out there.

    Genpeptide - 25% off peptides. An additional 10% discount of purchases over $1000. Valid June 26th to July 6th.
    -EDIT- FREEDOM25 is the discount code.

    Received via email marketing. Out of curiosity, I tested the code and it appears (as of this writing) that it will not apply to their "Build a Kit". Only one coupon code is allowed so it isn't stackable with the Peptide Critic 10% off code.


    NextGen Peptides is offering a sale as well. But since I don't see them on the preferred vendor list, I don't feel comfortable adding the specifics. But it's out there if you like them.
  • H

    One of the vendors I use mainly have test results from AFI. I cannot find any information about them anywhere on the internet. I have seen reddit posts stating they are fake. I have seen your review saying they are not, but it somehow still seems sketchy. Others have stated their methods for testing are not exactly up to Janoshik standards. At this point I don’t mnow what to believe and am just looking for a more believable reason to trust them. I have inventory that I have not touched because of this. Any help is appreciated. Thanks in advance


    @randy But how do you verify that it's not a fake AFI COA on a website (NTX peptide for example)? I don't see a way to validate with his website.
  • A

    Tucson-based company with a solid selection of research nootropics and powders. I find their peptides generally overpriced, but their bulk powders appear to be better value from my estimation. I’ve ordered from them several times without any issues and was generally happy with the product quality. I can verify their MT2 definitely gave my rat a dark tan.
    Unfortunately, my most recent order went wrong. I placed a ~$195 order that included four items, but they only shipped three, the $85 bottle of enclomiphene was missing. I emailed them twice regarding the missing item and never received a response. It’s disappointing that a relatively straightforward issue like this wasn’t addressed.
    I had a good experience with them previously, but this situation has made me hesitant to order again.

    UPDATE: After a couple more email attemps, they did make it right & sent me the missing package! Great vendor.


    Last week they shipped me a order containing 2 items. It was fulfilled as both items on their website. When it arrived it was only one of the items with a revised packing list stating the other item would ship seperate. It arrives tomorrow. Not saying they wont eventually go bad but currently at least they are mostly doing what they are supposed to.
  • E

    I noticed the majority of posts on this site with regard to Pinealon research because of sleep issues. I'm wanting neuro benefits of memory, clarity, etc.

    Is there anyone here who's gotten benefits other than better sleep?

    I also see most info favors researching it in morning hours. I don't want kitty to fall asleep at work...


    @Nuncles said: @stevepep Randy posted on another thread that he really noticed it at 2mg so I'm assuming he went with the higher dosage protocol. I'm doing the peptide dosages protocol of 1, 1.5. and 2 for 20 days. I'm using that protocol also, but leery of starting w/1mg.; I always half doses of just about everything. If this gives me slight headache and crazy dreams, I need to be real careful. Going to start on July 3 and go through long weekend, if all goes well. @randy Where are you?!
  • E

    I've heard of very few who have not regained their weight, sometimes more, once they stop Semi/Tirz/Reta. There are some that claim to not have regained the weight, or a large portion of it but no proof to back it up that I know of. It's possible; I just don't know any of them.

    Most of us here at least have the notion that we're probably going to be taking weight loss peptides for the rest of our lives, with the only other choice being micro-dosing, instead of higher doses.

    The 'therapeutic dose' of Tirz is 5mg, therefore, IMO, anything under that is micro-dosing. I know lots of experts are saying 2.5 or less are the levels, but that doesn't make sense to me. Whatever.

    I'm at 6 Tirz/1 Survo right now and after a month-long stall after dropping 30#'s, my weight is starting to drop again due to the Survo, albeit slowly. Think it's going to be this way for the next 20 lbs that I need to lose, unless I really exercise hard (Not likely)

    Anyone else considering micro-dose? Doesn't mean you have to give up the other peps, just the ones for weight loss.


    @jamiegallien said: My INTENT is to taper down Reta as slowly as I went up, while tapering up calories at the same time until I find maintenance. With that said, I have incorporated consistent meal prep, whole foods, hard weight training and other disciplines into my life that were not there before. I plan to keep those until I drop dead somewhere in the future as a fit, healthy, old man. God willing that will allow me to keep the weight off. I think the key is my "goal" isn't to hit a target weight. My goal is to be fit and stay that way the rest of my life. Too many hit their target weight and completely quit everything they were doing to get there. Bad news that. "May you live and long and healthy life, and die quickly." - Chinese proverb
  • E

    Note: If you want Tirz (Zepbound) from ELilly, you get quick pens, no other options. I'm spoiled now since joining this forum and want to determine my own doses but there are GREAT options now for those who want and need them.

    https://youtu.be/A-huqMRkvk4?si=L9erpJraVYs_7ypO


  • J

    I have taken MOTS-c since November (with breaks worked in). I have been doing 10mg per week, split into 3 injections. This past week I decided to split the same dosage into daily injections. I made it 1.5mg per day, for ease, so actually doing 10.5mg a week. I have never had the itchy welt others reported. Lowering my dosage, but doing it daily, they changed. After the 3rd day I have developed itchy welts. I am switching back, but this doesn’t make sense to me?


    @hisamjan Just an opinion…. Research benefits of working out in a fasted state vs working out with carbs. Also fasted cardio is good but should be timed separately from gym sessions. Lastly MotsC works good on fasted cardio, but less on pre gym.
  • MyBM

    Hey @Randy, you want to know how to get all the girls to swoon 😍 over ya?
    By doing a giveaway like this one! 🔥🔥🔥


    @BeeKind The contest accidentally closed at 12am June 30, I just reopened it i will close tonight and a winner picked tomorrow. Winner will be announced in the next newsletter.
  • A

    I am curious if anyone else has had experience with them, good or bad. My wife ordered GLP-3 for her research and has had great outcomes over the last 7 weeks. It seems like it’s a newer company and there isn’t a lot out there about them, so just curious about any feedback from the community.


    Protide was the first place i got my GLP3 from. Well packaged, COA online, Lot#'s matched what was printed on the bottle. The Chihuahua and his wife are both through the first bottle with no issues, seems to be working fine so far. I will say they are expensive as compared to some other vendors on here, some of which do the same level of testing.
  • M

    Like a lot of people here, I place a lot of faith in this site to recommend and vet out the Wild Wild West, aka the Peptide Vendors 🙂 After placing my order and pressing the go button, I was taken to some weird 3rd party payment processing system, which is not unusual for small companies but I was very surprised that the payment didn't go through 4 times two different credit cards. This company appears to be located in Las Vegas and I am in Seattle so there should be no problems. Finally one of my credit cards send me text message that they detected fraud. I replied yes Meaning it was not fraud and to process the payment. That finally went through. The name that came through on the credit card charge is Wert*ByteNFT. Which is very weird.

    But I think I am bothered more by the fact that they added an $8.42 "Route Shipping Protection" without the ability to remove this, which I definitely would have done. That alone, in my book, would turn them from 5-⭐ to 4-⭐

    1b4c7b9b-21d3-4557-9bcd-66f95288d6a0-image.jpeg

    76ca450d-7f25-458c-a4f0-688c38617df1-image.jpeg


    One clunky issue: When placing an order on PuraTek’s site, there’s no button or prompt to create an account. After checkout, I went back to track my order and had to make an account—only to find the order isn’t linked to it. This is a missed opportunity. Without saved shipping, billing, or payment info, every reorder or new purchase feels like starting from zero. A simple account creation option at checkout would make repeat business seamless and encourage loyalty. Instead, it’s just as friction-heavy as buying from any random vendor for the first time. This my first order from them certainly had quite a lot of friction to the point where I almost gave up and ordered from the next one on my list.