Equipment for doing your own testing
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Just saying...theyve got a good margin on that.
Talk to them like a grey market vendor and say "Hello Dear, I need sample before i make big order and do much business" Then the MOQ doesnt matter.
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Sorry about that. The link was with me logged in. Yes, it's AMC peptide vendor but I was not suggesting people buy peptides from there. I have in the past but not in the last year or more. Just happened to see recently that they sell equipment too. I found it interesting.
Again, apologies for not thinking the link through.
Joel
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@Reactive3078 - Bahahahha! Again, I'm not recommending the machine or AMCs peptides, I just didn't know that testing equipment that SUPPOSEDLY does the same tests we pay for, was attainable for us common folks. I own a winery and I KNOW how expensive equipment is. I assumed specialized peptide testing equipment would run, like winery equipment, $100-$250K minimum. I do have a small wine analyzer that tests for five or six things but even it runs $25K.
Randy you can take this down anytime brother, I'm not affiliated in any way other than I made 3-4 peptide purchases from AMC in 2024-25. Ha! It may be a piece of junk. Just thought it was interesting.
Joel
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Just saying...theyve got a good margin on that.
Talk to them like a grey market vendor and say "Hello Dear, I need sample before i make big order and do much business" Then the MOQ doesnt matter.
@Randy Oh my! That's quite a margin! And even more attainable than I thought! Hahaha. Now I feel like an idiot.
And in light of the Snake Pepskins quote under his name: “Knowledge is the ultimate power.
It’s not what you know that defines you, it’s that which you share, that defines you.”I REALLY feel like an idiot for sharing that link, Lol!
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People mix up three different questions:
Purity - what fraction of the UV-absorbing stuff is the main peak
Identity - is that peak the peptide on the label
Amount - how many mg of actual peptide are in the vialA used Agilent 1100/1200 + C18 column + 0.1 mg balance will do #1 and a version of #3. It will not do #2. FOr #2 you need a Mass Spec machine.
HPLC separates by hydrophobicity and measures peak area at 214/220 nm. Purity is just:
main peak area / all peak areasPractical cheap setup for HPLC: complete used 1100/1200 gradient HPLC with UV/DAD, one new C18, HPLC ACN/water/TFA, 0.1 mg balance. Ballpark $8–15k could be less on used lab equipment sites but need to make sure it has all the modules. Not easy to keep these machines working well without knowhow.
For identity of what is in the vial you need Mass Spec
Best cheap option: ESI single-quad LC-MSAgilent 6120/6130/6140, Shimadzu LCMS-2020, Waters QDa/SQD.
Used working ones usually ask $35k–$55k. “Powers on” eBay units at $8k–$20k are often dead. Also really tough to run and maintain - need nitrogen tank at home etc.
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People mix up three different questions:
Purity - what fraction of the UV-absorbing stuff is the main peak
Identity - is that peak the peptide on the label
Amount - how many mg of actual peptide are in the vialA used Agilent 1100/1200 + C18 column + 0.1 mg balance will do #1 and a version of #3. It will not do #2. FOr #2 you need a Mass Spec machine.
HPLC separates by hydrophobicity and measures peak area at 214/220 nm. Purity is just:
main peak area / all peak areasPractical cheap setup for HPLC: complete used 1100/1200 gradient HPLC with UV/DAD, one new C18, HPLC ACN/water/TFA, 0.1 mg balance. Ballpark $8–15k could be less on used lab equipment sites but need to make sure it has all the modules. Not easy to keep these machines working well without knowhow.
For identity of what is in the vial you need Mass Spec
Best cheap option: ESI single-quad LC-MSAgilent 6120/6130/6140, Shimadzu LCMS-2020, Waters QDa/SQD.
Used working ones usually ask $35k–$55k. “Powers on” eBay units at $8k–$20k are often dead. Also really tough to run and maintain - need nitrogen tank at home etc.
@BS That's good to know, and tracks with good winery equipment as I was thinking just a little lower priced. Fortunately I have Nitrogen and Argon gas here all the time for filling headspace in my barrels and tanks, but even so, not pulling the trigger on Mass Spec machine. Know winery equipment maintenance but not this type of equipment. Not maintaining it properly is probably the same though, untrustworthy outputs and failing equipment.
Thanks for your knowledge!
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@Randy Oh my! That's quite a margin! And even more attainable than I thought! Hahaha. Now I feel like an idiot.
And in light of the Snake Pepskins quote under his name: “Knowledge is the ultimate power.
It’s not what you know that defines you, it’s that which you share, that defines you.”I REALLY feel like an idiot for sharing that link, Lol!
@djoelcassell you are good. I had no idea this product existed so you sent me down the rabbit hole
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@djoelcassell you are good. I had no idea this product existed so you sent me down the rabbit hole
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