Popular weight loss drugs linked to a surprising fingernail problem
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https://www.sciencedaily.com/releases/2026/10/261011211604.htm
From Science Daily Mind and Brain page.
A reminder that we don't know all of the good or the bad stuff peps might be doing to us. Hopefully, in the long run the good will outweigh the bad for most every researcher.@mary
With the state of THEIR labs I would be surprised this is the ONLY problem found among "official" GLPs
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@ResearchCat just compare your fingernail growth rate with it and without it, do an experiment.
@bobs Not worth stopping taking either creatine or Klow to me. I have to cut my nails at least once a week, which is probably 3-4x more often than previously. And keeping my sasquatchness under control is almost an industrial scale endeavor.
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@bobs Yeah, I have been taking creatine for a few years so I can’t say what issues that is preventing. Aside from clickbait Youtube videos, there is nothing even slightly controversial about taking creatine daily forever.
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I am skeptical that this is anything other than what we already know, but given the number of people using these drugs, it’s good that the research is being done. It’s not exactly a revelation that when you starve yourself, your body begins to literally eat itself.
In this space, we are all over the place with respect to using GHK, collagen, or other things to counter side effects, but the handful of people I know who are using GLP-1’s to lose a lot of weight under a doctor’s supervision are basically in ‘I shit myself a lot and my hair is falling out’ mode.
Speaking of, I need to go to Costco and buy another vat of collagen.
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I am skeptical that this is anything other than what we already know, but given the number of people using these drugs, it’s good that the research is being done. It’s not exactly a revelation that when you starve yourself, your body begins to literally eat itself.
In this space, we are all over the place with respect to using GHK, collagen, or other things to counter side effects, but the handful of people I know who are using GLP-1’s to lose a lot of weight under a doctor’s supervision are basically in ‘I shit myself a lot and my hair is falling out’ mode.
Speaking of, I need to go to Costco and buy another vat of collagen.
@ResearchCat
I would love to see a study done with a second group taking GLPs with calorie restriction not exceeding 500 and focused on side effects and benefits only, not weight loss. -
@mary
With the state of THEIR labs I would be surprised this is the ONLY problem found among "official" GLPs@Stan-Douglas
Thanks for bringing that up...should have been the main topic...much more concerning! -
@ResearchCat what is your daily dosing? I dropped it from my daily due to weight gain. Cant remember but
Might have had joint issues with it too. It was something i didnt want at the time.@ogsteve standard 5g but i have tried 10g for a month. There are some folks recommending mega-dosing at 20g periodically for brain health and build phases. I did not enjoy 10g as I felt a bit bloated and swollen. It was oddly non-specific but in keeping with the expectation that one retains more water in the muscles.
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I take 15g a day. Half in mornings water bottle and the rest in afternoon. I very rarely have any of the drawbacks people have on most things. Same here. No gastro issues or bloating. I will say though I have been swollen and bloated most of my life so maybe I am now. Lol
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@ogsteve standard 5g but i have tried 10g for a month. There are some folks recommending mega-dosing at 20g periodically for brain health and build phases. I did not enjoy 10g as I felt a bit bloated and swollen. It was oddly non-specific but in keeping with the expectation that one retains more water in the muscles.
@ResearchCat I actually kinda like the 25 g dose for when I haven’t had enough sleep or feel kind of crappy. It really does add a boost. But I’m certainly not doing that every week.
I saw somewhere the other day that if you put it in a hot drink that it absorbs better or something. I don’t know maybe ought to have some tea.
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@mmp Yep; I was in a peptide state of mind.
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