CAGRI + RETA — New Nature Metabolism Study 🧬
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Is no one else concerned about fibrils with keeping reconned Cagri? I would have love to stayed on it for an appetite suppressant but I don't want to risk the chance of fibrils to form. If I could find 0.5mg or even 1mg vials of Cagri so I could just recon and inject and throw away the rest I would love that.
@denti There are some that say the fibrils debate is ignorant. Don't listen. Read the patent and understand that there is a scientific and medical reason for the concern. Though not a major issue if you handle the Cagri correctly. It's best kept at PH 4.5-5'ish, and when reconned with Hospira it ends up in the upper 5's, which is pretty good. Note: NN has several new patents that keep Cagri stable at higher PH's for their Sema-Cagri product.
This can back up those claims: https://pmc.ncbi.nlm.nih.gov/articles/PMC2634529/ While not definitive concerning Cagri, it's enough to cause pause. Jump to the Conclusion of the article if it is TLDR material for you.
I've had great luck with PGB Cagri. Their test of 3 vials has a variance of only around .1mg, so dosing is pretty accurate. It also recons with a PH of close to 5.8 with Hospira.
That being said, I wouldn't keep a reconned Cagri any more than 4 weeks. Only use Hospira bac.
I think you are smart and have the right idea. Better to play this game on the side of caution and think long term.
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@Juliano546 How's your research going?
@Juliano546 How's your research going?
any updates?
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@Juliano546 How's your research going?
any updates?
@MikeMiranda Little update on my Reta/Cag journey! I'm still consistently dropping around 1.5lbs a week and heavily enjoying the combination. Even better, my recent bloodwork showed positive improvements in my A1C! Those warning signs of prediabetes I was experiencing seem to be fading, so it's pretty damn exciting seeing the numbers moving in the right direction too!
I'll be making a slight increase from 266mcg to 300mcg of Cag this evening. Nothing crazy, just seeing how the combination continues treating me.
All in all, still loving the combination, and seeing those A1C improvements makes it that much sweeter!
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My ts is at high dose rt rn. What would would be my course of action to add cagri in? I know it starts as something like. ". 5mg" but do i drop the dose on rt oooor? Only thing that scares the hell outta my ts is getting super constipated. Other than that im just looking at the metabolism and synergistic benefits alone not really food noise reduction.
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My ts is at high dose rt rn. What would would be my course of action to add cagri in? I know it starts as something like. ". 5mg" but do i drop the dose on rt oooor? Only thing that scares the hell outta my ts is getting super constipated. Other than that im just looking at the metabolism and synergistic benefits alone not really food noise reduction.
@quicksilver80 miralax, fiber and probiotics help through the constipation. All I know about cag is to start super low especially pairing with reta
Just someone with a fridge full of research and a browser history that would concern my doctor.
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@quicksilver80 miralax, fiber and probiotics help through the constipation. All I know about cag is to start super low especially pairing with reta
@quicksilver80 miralax, fiber and probiotics help through the constipation.
100%! I have been taking miralax and fiber daily for months and it helps a lot. Even on 2-5mg tirz, my GI system pretty much locks up, and MiraLAX solves that - along with the ‘roids. Just make sure you drink plenty of water and get your electrolytes (It’s what plants crave!)
(And my gastroenterology specialist says it’s okay.)
Yeah, well, I’m just here for the research, man. - The Dude
If I haven’t liked your post, no offense. I have exceeded my daily allowance.
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@quicksilver80 miralax, fiber and probiotics help through the constipation.
100%! I have been taking miralax and fiber daily for months and it helps a lot. Even on 2-5mg tirz, my GI system pretty much locks up, and MiraLAX solves that - along with the ‘roids. Just make sure you drink plenty of water and get your electrolytes (It’s what plants crave!)
(And my gastroenterology specialist says it’s okay.)
@ResearchCat yeah. Im not saying i was the first but i definitely was an early pro fiber/prune juice guy lol. Its more my dosing im worried about specially doubling up with different antagonists
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@MikeMiranda Little update on my Reta/Cag journey! I'm still consistently dropping around 1.5lbs a week and heavily enjoying the combination. Even better, my recent bloodwork showed positive improvements in my A1C! Those warning signs of prediabetes I was experiencing seem to be fading, so it's pretty damn exciting seeing the numbers moving in the right direction too!
I'll be making a slight increase from 266mcg to 300mcg of Cag this evening. Nothing crazy, just seeing how the combination continues treating me.
All in all, still loving the combination, and seeing those A1C improvements makes it that much sweeter!
@Juliano546 That's fantastic news!
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@quicksilver80 miralax, fiber and probiotics help through the constipation. All I know about cag is to start super low especially pairing with reta
@BeeKind And water! Lots of water! I've never had any issues with constipation but last weekend opened my eyes to just how painful it can be.
Pretty sure I was too dehydrated for too long. I've never had pain like that. Based on what I saw, a lot of the issue was not staying hydrated at work. I hurt my back by straining so hard.
0/10 do not recommend. I won't let that happen again. It cost me my pride, a day out of my weekend, my virginity, and a chiropractor visit. -
@BeeKind And water! Lots of water! I've never had any issues with constipation but last weekend opened my eyes to just how painful it can be.
Pretty sure I was too dehydrated for too long. I've never had pain like that. Based on what I saw, a lot of the issue was not staying hydrated at work. I hurt my back by straining so hard.
0/10 do not recommend. I won't let that happen again. It cost me my pride, a day out of my weekend, my virginity, and a chiropractor visit.@DarkStar "my virginity"
bro! so rough! Sorry you had to experience these feelings 
yes definitely seconding the water. I was also advised to drink more water. Back to back high gravity in urine analysis trace oxatale crystals in the 2nd. So to avoid a kidney stone doc said drink more water. Its all I consume already, so im just gonna go drown myself that should suffice, right!!
First urine test popped bilirubin and trace blood so wanted to recheck then found oxalate crystal, but no bilirubin or blood so gotta wonder if peps can trigger false positives?
Now for the good news I am no longer pre diabetic I truly award this to Reta and also cannot help but feel Cag also played a hand while in conjunction.
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@quicksilver80 miralax, fiber and probiotics help through the constipation.
100%! I have been taking miralax and fiber daily for months and it helps a lot. Even on 2-5mg tirz, my GI system pretty much locks up, and MiraLAX solves that - along with the ‘roids. Just make sure you drink plenty of water and get your electrolytes (It’s what plants crave!)
(And my gastroenterology specialist says it’s okay.)
@ResearchCat yes love this
Brawndo!! The Thirst Mutilator!! -
@juliano546 Glad to ear about your progress! There are definitely many benefits of GLP-1’s beyond just the weight loss.
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@BeeKind And water! Lots of water! I've never had any issues with constipation but last weekend opened my eyes to just how painful it can be.
Pretty sure I was too dehydrated for too long. I've never had pain like that. Based on what I saw, a lot of the issue was not staying hydrated at work. I hurt my back by straining so hard.
0/10 do not recommend. I won't let that happen again. It cost me my pride, a day out of my weekend, my virginity, and a chiropractor visit.@DarkStar like ive so eloquently put it before. Id rather have the poops than trying to push a brick through the winking eye of a sharpei puppy all night. That being said. 20 ounces of prune juice might have been like bringing a machine gun to a bar room tussle so to speak.
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@DarkStar like ive so eloquently put it before. Id rather have the poops than trying to push a brick through the winking eye of a sharpei puppy all night. That being said. 20 ounces of prune juice might have been like bringing a machine gun to a bar room tussle so to speak.
That may be the best description yet. The poor puppy, though. He's going to get pinkeye for sure!
I likened it to trying to get dry dirt clods out of a rubber balloon without tearing it.
As disgusting as prune juice is, I would have welcomed it at that time. It didn't even occur to me. I'll take the machine gun.
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