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Tesamorelin cycling

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36 Posts 16 Posters 1.0k Views 2 Watching
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  • M Offline
    M Offline
    MikeMiranda
    wrote last edited by
    #25

    I would personally run one at a time to see the difference of each compound separately in different cycles.

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    0
    • ResearchCatR ResearchCat

      @neil-mccauley do you think 500mcg tesa/250mcg ipa separately w tesa am ipa PM would be a good starting range?

      N Offline
      N Offline
      Neil McCauley
      wrote last edited by Neil McCauley
      #26

      @ResearchCat said:

      @neil-mccauley do you think 500mcg tesa/250mcg ipa separately w tesa am ipa PM would be a good starting range?

      Do them both at same time. Ipamorelin is going to suppress somatostatin tone which will help not only increase the GH pulse from Tesa but also extend the pulse tail, thus resulting in more GH released. Separating them destroys the synergy, and is just more work, more pinning, more supplies, etc.

      I'd use a much lower dosage of Ipamorelin to start too. If you have the 10/3 blend, that's going to be 500mcg/150mcg. 150 seems low, but remember receptor saturation point starts at 1mcg/kg, so thats double that amount. If you're pulling them out of separate vials, I'd go 500/100.

      Remember, the higher the Ipa dosage the faster/more receptor desensitization will occur (and probably the same can be said about antibody build-up with Tesa). So it really is important to use lower end dosages and use outside methods to help things work synergistically.

      This is why I think really being strict about your fasted windows is hugely beneficial (3 hours prior/2 hours after). This will help amplify response and lesson the need for ever increasing dosages. Also, utilizing a 30 day cycle break after 90 days. Exercise is huge, as it lowers fasted insulin/glucose, again, allowing for a more favorable GH response. I think eating a higher protein, less junky carb diet and staying away from all day grazing/snacking and tightening up meal windows with no snacking in between is critical. So is DHEA supplementing if levels are < 300 (improves insulin sensitivity and helps restore GH pulse via several mechanisms).

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      • Mydogdaryl423M Offline
        Mydogdaryl423M Offline
        Mydogdaryl423
        wrote last edited by
        #27

        @neil-mccauley Appreciate the clarity in these posts.

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        • ResearchCatR Offline
          ResearchCatR Offline
          ResearchCat
          wrote last edited by
          #28

          @neil-mccauley Thank you, sir!

          Yeah, well, I’m just here for the research, man. - The Dude

          If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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          • C Offline
            C Offline
            coondogesq
            wrote last edited by
            #29

            @neil-mccauley @researchcat While I’m only doing 1 mg of Tesa, I suspect you may be tight that the aggregate of the two was too high. Stopping one dropped it to a more tolerable level. Which one I stopped may have been somewhat arbitrary at the time. Now that I’ve been on the Tesa for 7 weeks, it might make sense to add the ipa back. Going to daily be 5/2 makes some sense for the rest of my planned 14-16 week total Tesa cycle. Open to thoughts and advice. One of the reasons I like the exchanges here.

            As far as impact, tough to say for sure but my waist size is down 2 inches since starting Tesa and 6 inches since starting Reta the first week of June. The last two inches were with much less accompanying weight loss. I’m also noticing more rem and deep sleep time since starting Tesa.

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            • M Offline
              M Offline
              mikebricker
              wrote last edited by
              #30

              Question about recon Tesa. I usually filter with .22 micron filter when transferring from vial to pen vial.
              However, I’ve recently read that since Tesa is a large fragile molecule, filtering is not recommended.
              Is there any truth to that? @randy always filters and those videos are what got me on the filtering train…. 😉

              mmpM 1 Reply Last reply
              1
              • M mikebricker

                Question about recon Tesa. I usually filter with .22 micron filter when transferring from vial to pen vial.
                However, I’ve recently read that since Tesa is a large fragile molecule, filtering is not recommended.
                Is there any truth to that? @randy always filters and those videos are what got me on the filtering train…. 😉

                mmpM Offline
                mmpM Offline
                mmp
                wrote last edited by mmp
                #31

                @mikebricker said:

                filter with .22 micron filter

                Tesamorelin is 44-amino-acid peptide, ~5.1 kDa, hydrodynamic radius 1–2nm
                0.22 µm filter has 220nm pores

                The peptide is 100 times smaller than the filter's pore, so it easily passes through

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                • R Offline
                  R Offline
                  rmchrist
                  wrote last edited by
                  #32

                  Tesamorelin is one of the more fragile molecules...hence why a good practice is to use a reconstituted vial within 7 days.

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                  -1
                  • C Offline
                    C Offline
                    Commander
                    wrote last edited by
                    #33

                    I take Tesa 2mg / Ipa 6 days a week. The only reason I don’t take it 7 days a week is because I take Reta 2mg weekly. The night I take the Reta I don’t take anything else (at night). I havr been on it straight for 7 months and it has worked wonders. I don’t plan on stopping… I may drop the ipa here and there, but not the Tesa. It isn’t cheap, but nothing good is.

                    Please excuse my typos. Small Phone & Bad Eyes

                    S mmpM 2 Replies Last reply
                    1
                    • C Commander

                      I take Tesa 2mg / Ipa 6 days a week. The only reason I don’t take it 7 days a week is because I take Reta 2mg weekly. The night I take the Reta I don’t take anything else (at night). I havr been on it straight for 7 months and it has worked wonders. I don’t plan on stopping… I may drop the ipa here and there, but not the Tesa. It isn’t cheap, but nothing good is.

                      S Offline
                      S Offline
                      Shaqdiesel
                      wrote last edited by
                      #34

                      @Commander How much Ipa are you doing with the 2mg of Tesa?

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                      • C Commander

                        I take Tesa 2mg / Ipa 6 days a week. The only reason I don’t take it 7 days a week is because I take Reta 2mg weekly. The night I take the Reta I don’t take anything else (at night). I havr been on it straight for 7 months and it has worked wonders. I don’t plan on stopping… I may drop the ipa here and there, but not the Tesa. It isn’t cheap, but nothing good is.

                        mmpM Offline
                        mmpM Offline
                        mmp
                        wrote last edited by
                        #35

                        @Commander
                        What do you think would happen if you stopped tesa?

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                        0
                        • C Offline
                          C Offline
                          Commander
                          wrote last edited by
                          #36

                          Tesa 2mg / IPA .25mg
                          Not sure what would happen. But I finally get decent sleep and I lost a ton of visceral fat, I don’t want to go back..
                          I may experiment with dropping Ipa here and there and see if that helps boost it when I add it back in.

                          Please excuse my typos. Small Phone & Bad Eyes

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