GHK-Cu pain in my research rat
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Good Morning All.
My rat received his first research sample of 1mg of GHK-Cu. No effects to speak of for about an hour and then soreness in the injection site. This persisted all night as a low dull ache around the site (left rat thigh) and in the morning, felt somewhat under the weather with same persistant ache.
Looking for answers for my research rat!
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You are describing what many have experienced as well. My first week researching this, I had 2 nights out of a week, where it wasn't just a dull ache, it was a rude awakening to that awful sting, despite reconning with 6 extra ml of bac water for a 100mg vial. In my household it's labeled as the "Devil Incarnate" lol That sting lasted most of the night into the morning, which of course led to being very tired and somewhat exhausted. I quickly found a protocol to hep with it, called the "Anela protcol" for GHK-cu absolute game changer for me. I know there are folks that say, that introduces sterility risk, but I haven't had any issues following it.
What size vial and how much mg in the vial?
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Same experience. First dose was diluted x3 like Randy’s suggestion. Next day x10 and same reaction. 6 weeks later and I still have post inflammatory hyperpigmentation at the IS. I’ve read GHK can cause Mast Cell activation in some and I concluded that’s what I experienced.
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You are describing what many have experienced as well. My first week researching this, I had 2 nights out of a week, where it wasn't just a dull ache, it was a rude awakening to that awful sting, despite reconning with 6 extra ml of bac water for a 100mg vial. In my household it's labeled as the "Devil Incarnate" lol That sting lasted most of the night into the morning, which of course led to being very tired and somewhat exhausted. I quickly found a protocol to hep with it, called the "Anela protcol" for GHK-cu absolute game changer for me. I know there are folks that say, that introduces sterility risk, but I haven't had any issues following it.
What size vial and how much mg in the vial?
@WisGal64
It was tested at 35mg and sold as a discount since it didn’t meet the 50mg as intended. Couldn’t pass the price. Added 3mL of BAC. -
Good Morning All.
My rat received his first research sample of 1mg of GHK-Cu. No effects to speak of for about an hour and then soreness in the injection site. This persisted all night as a low dull ache around the site (left rat thigh) and in the morning, felt somewhat under the weather with same persistant ache.
Looking for answers for my research rat!
@elijahkpaugh
How many mg was the shot? -
I've had injection site reactions to it twice in the ten days I've been researching GHK-cu. Both times it was the inner thigh left and right. No reactions in the abdomen or glutes. Been injecting cold right out of the fridge so I'm going to start let it come up close to room temperature to see if that helps.
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@elijahkpaugh
How many mg was the shot?1mg (9 units)
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My wife does GHK-cu / KPV 1.67MG/.67MG - 10units per shot and she has no problems with it now. At first she did a little bit.
But the change she made was taking it out of the fridge and letting it sit for 10 minutes and she now uses a manual pen for it. She was using autopens for everything, but was having problems with ISR and bruising. She injects it a lot slower now and that seemed to fix it. -
As some have mentioned already, increase the bac water to dilute it, and use the inject in the glute, and I've been told that if you use a longer syringe 3/4-1in that it helps with the sting, the same person (who is a doctor) said you can massage the area afterwards because ghcku is not a delicate peptide. Which helps with dispersion and the sting. Full disclosure, I the glute injection site made the biggest difference for my research.
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As some have mentioned already, increase the bac water to dilute it, and use the inject in the glute, and I've been told that if you use a longer syringe 3/4-1in that it helps with the sting, the same person (who is a doctor) said you can massage the area afterwards because ghcku is not a delicate peptide. Which helps with dispersion and the sting. Full disclosure, I the glute injection site made the biggest difference for my research.
@Pepe.la.peptide
IM or SubQ? -
Subq, let me see if I can find the protocol
And post it. -
Found the protocol or rather best practices. Again, in the interest of transparency. I tried the micro doses in multiple places and that hurt more the the liquid so I stopped, and like I said earlier used the upper glute right below my belt line and I do massage it for about 10-15 min just with my hand. Oh and letting it warm a little works the research does for my pangolin is 15units.

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Check out this video from our very own @peptidecritic and @randy on GHK-cu dilution.
https://youtu.be/TV2OBcQsTD8 -
@WisGal64
It was tested at 35mg and sold as a discount since it didn’t meet the 50mg as intended. Couldn’t pass the price. Added 3mL of BAC.@elijahkpaugh
And how many units did you inject into that rat? -
@elijahkpaugh
And how many units did you inject into that rat?@Stan-Douglas The rat got 9 units for a goal of 1mg
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Check out this video from our very own @peptidecritic and @randy on GHK-cu dilution.
https://youtu.be/TV2OBcQsTD8@mrjoshua44 I did watch this before hand. I just didn’t have a sterile 5mL on standby for further dilution. That’s why it was only 3mL for 35mg. I think I’ve seen every video at least once now lol. The absolute best information out there!
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Update: Moved the site around with similar results. Dull pain in the area but not terrible, only slightly uncomfortable. Taking a short break until bigger vials and filters come in to dilute further.
Update 2: Also small quarter sized red rash at injection that is not painful.