Klotho / FLGR242 (albumin-bound new tech)
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Jeff- kindly relocate if not appropriate for a new category.
Multi-vial care package delivered today from BioLongevity, pinned both with 30 minutes between each. No site reactions, feel fine, great actually.
Super intrigued by both, I've done my homework. 60's male in great health, 2.5 year carnivore, focused on maximizing healthspan. Anyone else throwing caution to the wind and researching these two?
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@peptidepete I've been eyeing Klotho as well... any of your findings would be most interesting

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Awesome! FLGR242 is being described as "the fountain of youth" by one compounder we know and another is calling it "bollocks" I know alpha biomed is supplying biolongevity and paramount with the same thing. I may be a rat but I'm glad you are doing the research for us ;).
If this is a myostatin inhibitor without the risks/drawbacks it will change everything.
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R Randy moved this topic from Peptide Categories on
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Jay Campbell is going to be doing a interview with the inventor of FLGR 242 tomorrow night Sunday December 28th on YouTube and maybe elsewhere simultaneously I don't know. Should be fascinating
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Here is the YT recording with Dr. Farber, inventor of the FLGR242:
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I can confirm no injection site reaction whatsoever for either. Only 6 days in and nothing noticeable so far other than I had a very good X3 workout yesterday with very good numbers. I use the "electronic" X3 bar which measures all sessions and records to an app on my phone so will be an excellent objective measure of any FLGR benefits, I have 2.5 years of X3 sessions history

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1.5 weeks subsequent to initial injections. I feel...good. Subtle and squishy as hell description, but I know myself, and I feel...good. Different than I felt prior to dosing. Jay Campbell, who I personally find very hard to stomach, nevertheless, described the same result.
I am super stoked for dose #2 of both peps this Saturday. No neg sides at all. Stocked up with a several year supply- LFG...lol

For those who care, Liz Parrish and Jay Spall have many thought provoking interviews on YT. Shills or passionate bleeding-edge scientists? You'll have to form your own opinion. The science behind both Klotho and Follistatin is to me wholly compelling.
Are these peptides now a low-budget substitute for the Eterna plasmid therapies ($40k-$60k) or, Minicircle treatments? I think so, especially in combination with 2-3 annual courses of Epithalon for telomere lengthening. I did baselines with Clock Foundation and TrueDiagnostic a few weeks ago, awaiting the results...
Follow-up to my unposted post above: Now two full weeks since first sub-q's, did follow-up dosing this morning. A few hours later had a very good X3 workout. Increased my jumping jacks by 13% the past weeks. I feel very good. I like these, a lot.
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Several year supply? Costs as much as a car!
Keep us posted because price wise these ones are hard for most to pull off. Im currently waiting on a lab im friendly with to figure this one out and start mfg in china at a much lower cost.
@Randy said in Klotho / FLGR242 (albumin-bound new tech):
Several year supply? Costs as much as a car!
Keep us posted because price wise these ones are hard for most to pull off. Im currently waiting on a lab im friendly with to figure this one out and start mfg in china at a much lower cost.
At the prices of the moment, especially from Paramount, I totally agree.
I grabbed stock at three times around Christmas, BioLongevity Labs had the holiday discount which I added to with the additional Klotho/FLGR combo discount PLUS the 25% rebate on next order PLUS private discount links/discount codes Jay Campbell posted to the live chats during 3 live chats. Was able to get my cost down to approx $150/vial (so $600/mo total spend). Each time they opened ordering, they sold out within a day or two. Yes, it was still a comparatively significant outlay
but still a bargain compared to the only other option - gene therapy...
It's all relative right? lol...
Like you said above, to paraphrase, if these are as represented, they change everything. Each researcher has to place their own value on that

Side note- I thought of and went down the rabbit-hole yesterday of albumin-binding sites possibility of overload: CJC-1295 w/DAC + Triple agonist GLP + Klotho + FLGR242 (all albumin bound). Grok was amazing and provided me with a great analysis, which bottom-line said, this stack is theoretically good to go (low molar loads).
Onward upward
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@diegoc said in Klotho / FLGR242 (albumin-bound new tech):
Are you taking the Follostatin as well?
Yes. I feel great. I'm finding it difficult to not inject more frequently (no reason to!)
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Im definitely going to do Klotho, hopefully Randy can get the Chinese clone. Lol
I had a recent full body scan and the doc said that my heart was slightly larger and need to monitor in the future and i think Follostatin can increase the heart so i need to pass on that. 🥲
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Now fully embracing one vial per week FLGR242 dosing regimen. Just pinned my third vial in four weeks today. Zero ISR. Feel awesome. Nothing remotely close to any kind of negative effect.
Experimenting with pinning the Follistatin 48 hours separately from the αKlotho to avoid any possibility of crosstalk or albumin binding site competition, although in theory it should not occur. My biweekly Klotho pin is Sat AM (today is Thursday).
I feel great, awesome in fact, and find myself craving physical exertion and resistance band workouts. As previously noted I CRAVE both the Follistatin and αKlotho pins. Weird to say but best way to describe.
Not low cost = true. Crazy value = true. I am thrilled with the investment. A true fountain of youth for this 64 year old healthy man.
For those that care and can stomach Jay Campbell, he posted another live video on YT with Mike Farber the inventor of both. Worth the pain to watch it.
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Weight down, body fat down, lean mass up. The holy grail. Want to get another two weeks under my belt and I'll post specifics. InBody H30 bioimpedance scale. Still on FLGR242 Follistatin 5mg every week and the Klotho once every 2 weeks. Feel awesome, no sides other than feeling awesome everyday and good sleep. Also, continue to crave my X3 Force workouts, much more so than I ever did previously, the numbers are improving, another objective measure.
Comfortable fitting in 31" jeans, not been the case in many decades
I am also on other peps (Tesa/CJC/Ipa/GLP3/MOTS/NAD+/GHK/etc) -
My X3 workouts (2.5 years of app-logged workout history) are now personal bests every time. My vascularity is far greater than it has ever been. I am not nor have ever been a gym rat kind of guy, just a 65 year old dude who wants healthy muscles for healthy aging and insulin sensitivity. My body fat is burning off very nicely. Still doing the FLGR-242 every week 5mg, and the a-Klotho one vial biweekly. Still crave injection days, and hardest is not injecting more of both (counter-productive) because I feel so good.
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My X3 workouts (2.5 years of app-logged workout history) are now personal bests every time. My vascularity is far greater than it has ever been. I am not nor have ever been a gym rat kind of guy, just a 65 year old dude who wants healthy muscles for healthy aging and insulin sensitivity. My body fat is burning off very nicely. Still doing the FLGR-242 every week 5mg, and the a-Klotho one vial biweekly. Still crave injection days, and hardest is not injecting more of both (counter-productive) because I feel so good.
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