Tesa vs CJC?
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Correct. Hard to remember sometimes just going off top of my head without being in the lab and looking!
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I am at Tesa 2mg/ / IPA .25mg and have been for months.
The weird thing is my wife did that dose (she was normally at 1.6) the other night and had a bad reaction. She has been on Tesa/Ipa for months with no problems.
The reaction was weird, all bumps where she had been taking the Tesa before and raised heart rate. -
You may play with lowering Ipamorelin dose. 0.1 mg is known to saturate the receptor for the most.
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Right, I get all that, but testosterone and IGF-1 should be separate pathways and separate readings.
What were your IGF-1 results during that timeframe?
@hunt_ak I only did one full panel test about two weeks ago, and I didn't have a single out-of-range result. I can take a look when I get home. I use Rhythm monthly, and they don't measure IGF-1. I am simply stating my before and after results using CJC1295/IPA. The blood doesn't lie. I am off my cycle of CJC/IPA and now on Kisspepin, so I am interested to see what happens. Like I said, I am not alone in seeing increases in SHBG, Free and Total, when using CJC/IPA. I won't mess with Tesa because of the side effects people have had. I might if my IGF-1 was out of range but it wasn't.
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@hunt_ak I only did one full panel test about two weeks ago, and I didn't have a single out-of-range result. I can take a look when I get home. I use Rhythm monthly, and they don't measure IGF-1. I am simply stating my before and after results using CJC1295/IPA. The blood doesn't lie. I am off my cycle of CJC/IPA and now on Kisspepin, so I am interested to see what happens. Like I said, I am not alone in seeing increases in SHBG, Free and Total, when using CJC/IPA. I won't mess with Tesa because of the side effects people have had. I might if my IGF-1 was out of range but it wasn't.
@Stevepep I'm a fan of the CJC/IPA as well. Did you possibly mean 'increases in SHBG' meaning a decrease? Or were you too low and needed more protein binding to the free test?
Great discussion here. The synergistic affects of IGF-1 and test/free test along with the SHBG is interesting to watch.
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@Stevepep I'm a fan of the CJC/IPA as well. Did you possibly mean 'increases in SHBG' meaning a decrease? Or were you too low and needed more protein binding to the free test?
Great discussion here. The synergistic affects of IGF-1 and test/free test along with the SHBG is interesting to watch.
@hunt_ak it was out of range low 3 months ago now it’s in range but on the high side. I work out like an animal so the Rythm AI is saying I need more protein intake and maybe food before i do cardio and possibly longer recovery. Points to sleep as well. My estrogen is high (that’s my only out of range biomarker) which has a similar recommendation. It’s always a work progress but I feel like I am 20 and I am in my 50’s.
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Always a work in progress is for real. I'm behind you in my 40's but am in the best shape of my life and look better than most 20yo's currently. I wish we had access to some of these blood labs but up here in the cold North, they can't service these areas due to lengthy shipping times.
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@hunt_ak I only did one full panel test about two weeks ago, and I didn't have a single out-of-range result. I can take a look when I get home. I use Rhythm monthly, and they don't measure IGF-1. I am simply stating my before and after results using CJC1295/IPA. The blood doesn't lie. I am off my cycle of CJC/IPA and now on Kisspepin, so I am interested to see what happens. Like I said, I am not alone in seeing increases in SHBG, Free and Total, when using CJC/IPA. I won't mess with Tesa because of the side effects people have had. I might if my IGF-1 was out of range but it wasn't.
@Stevepep this is pretty impressive. I have about 29 out or range markers. Fixed several between the last two labs but still have some works in progress.
One of the things nobody tells you when they are selling you these labs is what happens when you get a bunch of red flags and what to do about them. And the clinician notes are kinda worthless.
I like the idea of the Galleri test, but also: Do I really want to know if there is a 95% chance I get one of 13 different kinds of cancer in the next 20 years? (Really think about it.)
And to hunt_ak’s point, I am in better shape now than in decades and in better shape than most people a lot younger than me.
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@hunt_ak it was out of range low 3 months ago now it’s in range but on the high side. I work out like an animal so the Rythm AI is saying I need more protein intake and maybe food before i do cardio and possibly longer recovery. Points to sleep as well. My estrogen is high (that’s my only out of range biomarker) which has a similar recommendation. It’s always a work progress but I feel like I am 20 and I am in my 50’s.
@Stevepep I was advised to take Highly Branched Cyclic Dextrin pre high output cardio and endurance workouts in a consultation with a sports physiologist. I was a little skeptical as I'm not a big fan of drinking carbs, but I gave it a go, loaded 25 -50 grams pre workout and 25 -50 grams post workout (depending on length and durations of the workouts 1 or 2 hours) and I can say it definitely supoorrted higher outputs and better recovery with no weight gain/water retention from adding 50-100 grams of carbs liquid carbs to my diet almost the opposite weight down on the scale but muscles are loaded.
I don't use it on stregth days but having the glycogen where it should be the following day and being recovered is making for better strength days also.
I think you box and run, those would be good days to try it, I'm finding this stratagy a simple way to get the macros that might be missing to support higher output training.
Anyways you may already know about this but thought I would share my experience, when I was told I need more marco intake based on training.
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@Stevepep I was advised to take Highly Branched Cyclic Dextrin pre high output cardio and endurance workouts in a consultation with a sports physiologist. I was a little skeptical as I'm not a big fan of drinking carbs, but I gave it a go, loaded 25 -50 grams pre workout and 25 -50 grams post workout (depending on length and durations of the workouts 1 or 2 hours) and I can say it definitely supoorrted higher outputs and better recovery with no weight gain/water retention from adding 50-100 grams of carbs liquid carbs to my diet almost the opposite weight down on the scale but muscles are loaded.
I don't use it on stregth days but having the glycogen where it should be the following day and being recovered is making for better strength days also.
I think you box and run, those would be good days to try it, I'm finding this stratagy a simple way to get the macros that might be missing to support higher output training.
Anyways you may already know about this but thought I would share my experience, when I was told I need more marco intake based on training.
@bfuller I don't this sounds like great advice. I talked to my Doc and she said my workouts are way too hard for my carb intake and that may be why my Estrogen levels keep going up. She thinks its related to recovery, carbs and more protein. I am a total nut and addicted if I don't work out I feel like garbage. She wants me to take off more days. Like two no workout days at all, no lifting, running, nothing. I just can't do that. So I am doing one day now to see how it goes. Drinking organic protein everyday with my creatine so I will try this as well.
We seem to be on similar paths. I just PM's you can you recommend a brand.
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Always a work in progress is for real. I'm behind you in my 40's but am in the best shape of my life and look better than most 20yo's currently. I wish we had access to some of these blood labs but up here in the cold North, they can't service these areas due to lengthy shipping times.
@hunt_ak We have a couple of people that are lunatics like us. I think @bfuller is with us as well. Constantly monitoring and pushing the limits on exercise. How much more can I lift, how much further and faster can I run. I seem to be in constant competition, mostly with myself. I also married a much younger hottie so I feel the need to focus on longevity.
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@hunt_ak We have a couple of people that are lunatics like us. I think @bfuller is with us as well. Constantly monitoring and pushing the limits on exercise. How much more can I lift, how much further and faster can I run. I seem to be in constant competition, mostly with myself. I also married a much younger hottie so I feel the need to focus on longevity.
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@Stevepep Haha yup, I'm 51 and wifey is 39 ! This social behaviour may be driven from the pheromones of a younger mate? We need a study to prove this theory and make a peptide out of it.
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My peptide bestie is 49 to his GF’s 28. He is on all the help.
@ResearchCat ......Nice....he probably has probably compiled a pretty good recipe/playbook I imagine.
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Yeah, we research a lot of the same protocols but I am 10 years older and married 25 years, so he needs more energy and stimulation.
Edit: and he is massive and I am puny.
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@jborja @researchcat @commander I don't get this I know Tesa is supposed to stimulate growth hormone, but the research is on abdominal fat in AIDS patients. I use CJC/IPA and saw all of my testosterone levels increase on my monthly blood testing, so I have factual proof it works. I take it at night, probably never more than 2 -3 hours fasted. SHBG up 29% to optimal, Free up 36% to optimal, and total up 43% to 874, also optimal. The proof is in the blood work. For whatever reason, my Estrogen is my only marker that is not average or optimal. It may be related to recovery, sleep, and stress. I can't listen to Josh with his cocky I know everything because I am tatted up, steroid abuser. I think he actually knows less than most of us on here. Why he hasn't been shut down makes no sense.
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I believe the issue is blood sugars, when they're elevated it contributes to somatostatin which is the growth hormone blocking hormone. Some people will fast and still have high blood sugars from having some insulin resistance, which imo needs to be addressed so that we're not getting water retention and carpal tunnel sides without the benefits.
With reta if you're still digesting dinner after 2 hours your blood sugars will still be elevated.
I'm currently working on getting my fasting blood sugars routinely 90 or under before I start gh or gh releasers. for what it's worth I'm still trying to figure alot of peptide information out and I may be off base but hopefully it adds to the discussion
I believe the issue is blood sugars, when they're elevated it contributes to somatostatin which is the growth hormone blocking hormone. Some people will fast and still have high blood sugars from having some insulin resistance, which imo needs to be addressed so that we're not getting water retention and carpal tunnel sides without the benefits.
With reta if you're still digesting dinner after 2 hours your blood sugars will still be elevated.
I'm currently working on getting my fasting blood sugars routinely 90 or under before I start gh or gh releasers. for what it's worth I'm still trying to figure alot of peptide information out and I may be off base but hopefully it adds to the discussion
Your body, in an evolutionary adaptation, knows that if you've eaten food, you don't need GH to break down stored fat, so it shuts down the whole GH assembly line.
I wouldn't wait to get your fasted glucose under 90 to start GH boosters, especially if you're over 40. Often these drugs in of themselves can actually improve insulin sensitivity over time via improved lypolisis. Definitely try the secretagogue path first to see how well you respond.
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I believe the issue is blood sugars, when they're elevated it contributes to somatostatin which is the growth hormone blocking hormone. Some people will fast and still have high blood sugars from having some insulin resistance, which imo needs to be addressed so that we're not getting water retention and carpal tunnel sides without the benefits.
With reta if you're still digesting dinner after 2 hours your blood sugars will still be elevated.
I'm currently working on getting my fasting blood sugars routinely 90 or under before I start gh or gh releasers. for what it's worth I'm still trying to figure alot of peptide information out and I may be off base but hopefully it adds to the discussion
Your body, in an evolutionary adaptation, knows that if you've eaten food, you don't need GH to break down stored fat, so it shuts down the whole GH assembly line.
I wouldn't wait to get your fasted glucose under 90 to start GH boosters, especially if you're over 40. Often these drugs in of themselves can actually improve insulin sensitivity over time via improved lypolisis. Definitely try the secretagogue path first to see how well you respond.
@Neil-McCauley cool, im 44 and fairly close to what I was shooting for anyway (had an 89 fbg yesterday, personal best) and have a couple pens ready for some tesamorelin and ipamorelin.
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