New blend: Metaboflex??
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https://southernaminos.com/product/metaboluxe-120mg/
Thoughts?
Anyone stack these 3 alrdy?
Thoughts from 5.5 Pro
How they could theoretically help each other
- NAD+ + 5-Amino-1MQ: “supply + conservation”
The theoretical pairing is coherent:
- NAD+ / NAD precursors aim to raise or support the NAD pool.
- 5-Amino-1MQ inhibits NNMT, an enzyme that methylates nicotinamide. Since nicotinamide can feed NAD salvage, NNMT inhibition is hypothesized to reduce nicotinamide loss and support NAD availability.
That said, this is not the same as proving better human outcomes. The strongest human NAD evidence is biomarker-based, and 5-Amino-1MQ has not been clinically validated for metabolic enhancement in humans.
- MOTS-c + NAD+: mitochondrial stress signaling + cellular fuel economy
MOTS-c is framed as a mitochondrial stress-response peptide, while NAD biology is central to mitochondrial redox and energy metabolism. The theoretical synergy is:
- MOTS-c pushes metabolic adaptation, especially around skeletal-muscle glucose use.
- NAD+ availability may support the intracellular machinery needed for energy turnover and repair signaling.
This is mechanistically plausible but not clinically proven.
- MOTS-c + 5-Amino-1MQ: exercise-mimetic overlap
MOTS-c is linked to exercise-induced metabolic signaling, and 5-Amino-1MQ showed additive effects with exercise in aged mice. That makes the pair theoretically interesting for:
- skeletal muscle metabolism,
- insulin sensitivity,
- exercise tolerance,
- body-composition remodeling.
But the evidence is animal-heavy. A current ClinicalTrials.gov listing describes a Phase 2a trial evaluating investigational MOTS-c versus placebo in adults with prediabetes and overweight/obesity, which means human efficacy is still being actively tested rather than established.
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I couldn't look at the product without creating a profile.
They better come up with a new name, Metabo Flex is already taken.
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i usually shy away with anything that sounds like a 90s bodybuilding magazine gimmick. even wolverine just sounds kinda lame even though i know it works. like...is pam anderson gonna ride out on a fatbob carrying mac 11's with pantera screeching in the background? lol
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@quicksilver80 where do you come up with this LOL
You are quite funny
@WisGal64 im pretty sure that was a movie called barbed wire i was referencing.
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i usually shy away with anything that sounds like a 90s bodybuilding magazine gimmick. even wolverine just sounds kinda lame even though i know it works. like...is pam anderson gonna ride out on a fatbob carrying mac 11's with pantera screeching in the background? lol
I feel you, culture assigns all kinds of dumb names to good things.I think I was just surprised with there being more than just glow and klow, I’m still new to the scene.
Since this post I’ve learned there are many more blend hypotheses.
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I think some of these new blends are just jumping on the bandwagon. I like Glow/Klow, and the balance is okay. The problem with a lot of the newer ones is that if the specific blend doesn’t suit your research needs, it’s kind of pointless.
I have run protocols of most of the above but not in a way conducive to having them in a single vial. I typically run them separately or overlapping. And someone here was talking about research recommending you don’t take MOTS-C and NAD+ together(at the same time) and this blend seems to contradict that.(I don’t have the background for that assertion.)
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I feel you, culture assigns all kinds of dumb names to good things.
I think I was just surprised with there being more than just glow and klow, I’m still new to the scene.
Since this post I’ve learned there are many more blend hypotheses.
@Splinter i really wish they would rename one of those because conversationally its like their and there. OH YOU MEAN GLOW? every time im talking about peps. lol. should make a peptide drinking game, i would die.
