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Peptide Critic Community

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  4. Lab vs Lab, We tested 5 Labs using the same Kit.
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Lab vs Lab, We tested 5 Labs using the same Kit.

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  • RandyR Online
    RandyR Online
    Randy
    wrote last edited by Randy
    #1

    New Multi‑Lab COA Deep Dive: Why Test Results Vary Between Labs

    infographic Lab v Lab.png

    We just published a new breakdown on a multi‑lab retatrutide test that should be interesting for anyone who actually reads COAs instead of just the bold numbers.

    In this run, the same "Uncle Wang" Retatrutide 10 mg kit from Nexaph was tested by six different labs: AFI, Freedom Diagnostics, Janoshik (vendor and third‑party), TrustPointe Analytics, and Vanguard Laboratory. The labs all agreed on the big picture: identity confirmed as retatrutide and very high purity (roughly 99.7–99.9%+ depending on the report).

    Where things got spicy was the mass / net content. Reported content ranged from about 10.18 mg up to 12.80 mg per vial, with some labs clustering low (AFI, Vanguard) and others higher (Freedom, TrustPointe, Janoshik). Instead of treating that spread as “who’s lying,” we walk through why those numbers can legitimately differ across methods, calibration curves, sample prep, vial selection, and how each lab defines and calculates content.

    https://peptidecritic.com/blog/why-test-results-vary-between-labs-multi-lab-coa-comparison

    "If it doesnt come in a needle. It doesn't work"

    1 Reply Last reply
    16
    • mrjoshua44M Online
      mrjoshua44M Online
      mrjoshua44
      wrote last edited by
      #2

      Fantastic article!! See, this is why I love this space. Just gets down to the brass tacks with a no, nonsense approach. I learn so much from this platform everyday.

      1 Reply Last reply
      2
      • S Offline
        S Offline
        STATIEEIGHT
        wrote last edited by
        #3

        Awesome work & sorta what I thought would be found.

        One question - were the labs sent more than 1X vial aware they were all from the same source/you?

        RandyR 2 Replies Last reply
        0
        • Ctrain24C Offline
          Ctrain24C Offline
          Ctrain24
          wrote last edited by
          #4

          Thank you for another great article. I always reconstitute based off the COA which is almost always from one lab. With labs varying on how much is in the vial is calculated dosages that way really the best way?

          1 Reply Last reply
          2
          • V Offline
            V Offline
            ValGal
            wrote last edited by
            #5

            Great article. Thanks Randy and Jeff.

            1 Reply Last reply
            0
            • A Offline
              A Offline
              Aps32
              wrote last edited by
              #6

              Excellent information. Thank you for diving deep and sharing your findings!

              1 Reply Last reply
              0
              • S STATIEEIGHT

                Awesome work & sorta what I thought would be found.

                One question - were the labs sent more than 1X vial aware they were all from the same source/you?

                RandyR Online
                RandyR Online
                Randy
                wrote last edited by
                #7

                @STATIEEIGHT 2 vials from the kit sent to each lab, plus the Jank result from 3rd party test on thr same batch and the vendors 2nd party test from jano on the same batxh.

                "If it doesnt come in a needle. It doesn't work"

                1 Reply Last reply
                0
                • JustAgirlJ Offline
                  JustAgirlJ Offline
                  JustAgirl
                  wrote last edited by
                  #8

                  Love the info and REALLY love those labels on the vials, hilarious and so freaking creative. Thank you for this!

                  RandyR 1 Reply Last reply
                  1
                  • N Offline
                    N Offline
                    Neil McCauley
                    wrote last edited by
                    #9

                    I ain't upset that Nexaph overfills its vials a tad

                    1 Reply Last reply
                    3
                    • WisGal64W Offline
                      WisGal64W Offline
                      WisGal64
                      wrote last edited by
                      #10

                      This is by far, one of the best write ups I’ve seen yet thank you for sharing this

                      “Currently in a committed relationship with my plateau. Waiting for my receptor reset to file for divorce”

                      1 Reply Last reply
                      3
                      • C Offline
                        C Offline
                        Chuxpeps
                        wrote last edited by
                        #11

                        As I've come to expect from @randy, science is explained in simple, understandable terms that provide real-world applicability while calling out the "Stone Tablet" argument of COA's from any particular lab. I followed this original discussion with great interest and am delighted to see this write-up. Thanks for the time, money, and effort you spent on this.

                        1 Reply Last reply
                        3
                        • P Offline
                          P Offline
                          PeptidePete
                          wrote last edited by
                          #12

                          Awesome, thank you very much for the research!

                          1 Reply Last reply
                          0
                          • S STATIEEIGHT

                            Awesome work & sorta what I thought would be found.

                            One question - were the labs sent more than 1X vial aware they were all from the same source/you?

                            RandyR Online
                            RandyR Online
                            Randy
                            wrote last edited by
                            #13

                            @STATIEEIGHT John at AFI is a friend (we still pay him). The rest of them probably saw peptide critic on the credit card if they were looking for it.

                            "If it doesnt come in a needle. It doesn't work"

                            1 Reply Last reply
                            0
                            • JustAgirlJ JustAgirl

                              Love the info and REALLY love those labels on the vials, hilarious and so freaking creative. Thank you for this!

                              RandyR Online
                              RandyR Online
                              Randy
                              wrote last edited by
                              #14

                              @JustAgirl I bought a sticker maker thinking id do something funny...i never thought it would involve unc wang.

                              "If it doesnt come in a needle. It doesn't work"

                              1 Reply Last reply
                              0
                              • R Offline
                                R Offline
                                rogerp
                                wrote last edited by rogerp
                                #15

                                I just watched a video that said the true way to test if a product is what it actually is sold as is to have it tested with Liquid Chromatography-Mass Spectrometer (LC-MS) to actually tell if it actually the correct peptide. I thought that is what a purity test covered, but looking at this image above, I guess I am wrong.

                                What vendors are tested like that and what testing labs are actually using this? I see Freedom might be, if I am reading that right.

                                I apologies in advance, new to COA process and trying to learn more on it.

                                video that I randomly came across:
                                https://youtu.be/lHUOLJHiJzA?si=9P0QJVayqogka9fc&t=488

                                1 Reply Last reply
                                0
                                • I Offline
                                  I Offline
                                  islander671
                                  wrote last edited by
                                  #16

                                  I don't see reta on their website, will they be selling or sold reta? New to this world, and this is seems to be a signal of who to trust in a world that seems really hard to find a trustworthy provider.

                                  RandyR 1 Reply Last reply
                                  0
                                  • J Offline
                                    J Offline
                                    jborja
                                    wrote last edited by
                                    #17

                                    My guy. Easy to digest, follow and read. Straight to the facts and points. Pulitzer Emmy, you name it.

                                    1 Reply Last reply
                                    1
                                    • I islander671

                                      I don't see reta on their website, will they be selling or sold reta? New to this world, and this is seems to be a signal of who to trust in a world that seems really hard to find a trustworthy provider.

                                      RandyR Online
                                      RandyR Online
                                      Randy
                                      wrote last edited by
                                      #18

                                      @islander671 nxp-3p 😉

                                      "If it doesnt come in a needle. It doesn't work"

                                      1 Reply Last reply
                                      0
                                      • B Offline
                                        B Offline
                                        burner1
                                        wrote last edited by
                                        #19

                                        Well done.
                                        Soooo... I was right? I kid I kid !!! 😜

                                        1 Reply Last reply
                                        1
                                        • F Offline
                                          F Offline
                                          flyhigh
                                          wrote last edited by
                                          #20

                                          Excellent.

                                          1 Reply Last reply
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