Beginner question Trizapetide
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When reconstituting- how do you decide how much bac water to use? 1ml vs 2ml ?
2.12mg Tirzapetide desired dose in a 20 mg vial
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It's all a matter of how many units you want to pull, I like to keep them at 15, 20, or 25.
Playing around with the Pep Calc you can find at the top under Calc&Tools it looks like you want 1.9mL for that very specific dose.
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I think your desire for dose accuracy is a deciding factor easier to draw 20 units w 3 ml than to try to draw 6.6 units with only 1 mL
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You will have to soon understand the math of mg/ml concentration of your reconstituted solution. That decides your units for desired dose.
Example:
If you put 1ml BAC in 10mg vial that's 10/1 = 10mg/ml concentration, which is 10mg per 100 units, so if you want 2mg dose since 2mg is 1/5 of 10mg, 100 units / 5 = 20 units for 2mg dose.
If you put 2.5 ml (250 units) BAC in 10mg vial, that gives you 10/2.5 = 4mg/ml concentration 4mg in 100 units. Then 2mg dose is 0.5ml or 50 units.
Some prefer more dilution some less. That's the beauty of RUO peps, to each his/her own.
General guideline: keep amount of BAC volume that fully divides the mg quantity of vial. That keeps math simple to calculate units.
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You will have to soon understand the math of mg/ml concentration of your reconstituted solution. That decides your units for desired dose.
Example:
If you put 1ml BAC in 10mg vial that's 10/1 = 10mg/ml concentration, which is 10mg per 100 units, so if you want 2mg dose since 2mg is 1/5 of 10mg, 100 units / 5 = 20 units for 2mg dose.
If you put 2.5 ml (250 units) BAC in 10mg vial, that gives you 10/2.5 = 4mg/ml concentration 4mg in 100 units. Then 2mg dose is 0.5ml or 50 units.
Some prefer more dilution some less. That's the beauty of RUO peps, to each his/her own.
General guideline: keep amount of BAC volume that fully divides the mg quantity of vial. That keeps math simple to calculate units.
@pep_researcher said in Beginner question Trizapetide:
General guideline: keep amount of BAC volume that fully divides the mg quantity of vial. That keeps math simple to calculate units.
Very true. If it's Tirzep, for me (to each her own), between 30 & 75 in the syringe is most comfortable.
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The compounding pharmacy I used to buy from seemed to like standardizing on a 50 unit shot. I tend to prefer 10-20 units for most peps. One thing to keep in mind is that the larger the shot, the less loss there will be due to mistakes or process.
That is, losing 1 unit of a 5 unit shot is a bigger deal than losing 1 unit of a 40 unit shot. Ultimately, it comes down to whatever you’re most comfortable with as long as your math is right and you are dosing correctly.
GLP-1’s are one peptide where you do not want to calculate incorrectly.
