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Energy Peptides Question

Scheduled Pinned Locked Moved Peptide Discussion
nadmots-css-31
40 Posts 16 Posters 2.2k Views 2 Watching
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  • B Offline
    B Offline
    brandenscheidecker
    wrote on last edited by
    #21

    don't waste your money on the test gel, either go with a test booster like Enclomiphene you can buy it from several vendors I have even seen it on grey. Plenty of TRT replacement services out there that do telehealth and labs. 100-200 bucks per month, a lot primary care DRs will send you to a endocrinologist who thinks 300 is a healthy lvl for older men and wont prescribe it, skip them just wasting your time.

    Rythm health labs will tell you everything you need to know! is cheaper than going to my DR a lot of telehealth services will accept there labs as well.

    N 1 Reply Last reply
    2
    • B brandenscheidecker

      don't waste your money on the test gel, either go with a test booster like Enclomiphene you can buy it from several vendors I have even seen it on grey. Plenty of TRT replacement services out there that do telehealth and labs. 100-200 bucks per month, a lot primary care DRs will send you to a endocrinologist who thinks 300 is a healthy lvl for older men and wont prescribe it, skip them just wasting your time.

      Rythm health labs will tell you everything you need to know! is cheaper than going to my DR a lot of telehealth services will accept there labs as well.

      N Offline
      N Offline
      Neil McCauley
      wrote on last edited by Neil McCauley
      #22

      @brandenscheidecker said in Energy Peptides Question:

      don't waste your money on the test gel, either go with a test booster like Enclomiphene you can buy it from several vendors I have even seen it on grey. Plenty of TRT replacement services out there that do telehealth and labs. 100-200 bucks per month, a lot primary care DRs will send you to a endocrinologist who thinks 300 is a healthy lvl for older men and wont prescribe it, skip them just wasting your time.

      Rythm health labs will tell you everything you need to know! is cheaper than going to my DR a lot of telehealth services will accept there labs as well.

      Enclomiphine is a young man's compound. It relies on using your endogenous HTPA in order to be effective, i.e. essentially jump-starting your own system. This man is 67, and that horse has left the barn, decades ago. His HTPA is simply not youthful enough to produce enough testosterone to move the needle. If he was 35 - 45, maybe that would buy him 5 to 10 years maximum, but thats a moot point now. Going to have to go exogenous now.

      Secondly, hundreds of millions of patients worldwide use transdermal testosterone to great effect. Simply look at the sales and numbers. You never hear about them because 99% of those patients aren't online talking about it on a message board. Message boards are overrepresented with younger people using AAS and similar compounds in supra physiological dosages, so of course they will poo poo on using a gel given their history of pinning test and related AAS.

      The real fact is that a majority of people on HRT do so with compounded gels, and have great results with it. It's far more convenient to use a gel over pinning for a plethora of reasons, which is why it is generally tried first to see if it works for you. If you're a non responder due to various reasons, usually someone who doesn't absorb well, then you can always switch to injects afterwards, no big deal. Many, in fact most, absorb well, OP herself as she mentioned.

      1 Reply Last reply
      1
      • B Offline
        B Offline
        brandenscheidecker
        wrote on last edited by
        #23

        hell no give him something that works lol once a week IM will change his life.

        N 1 Reply Last reply
        0
        • B brandenscheidecker

          hell no give him something that works lol once a week IM will change his life.

          N Offline
          N Offline
          Neil McCauley
          wrote on last edited by Neil McCauley
          #24

          @brandenscheidecker said:

          hell no give him something that works lol once a week IM will change his life.

          At his age of 67, absolutely. Going from very low T to pinning 100mg/week and pushing your T into the 600 to 900 range will be a drastic improvement in energy and overall quality of life. Expect fat loss, muscle gain, improvements in sleep, blood pressure, and glucose measurements as well. There is a reason why TRT is so popular.

          Many go on TRT way to early in life when lifestyle changes can improve T levels drastically. However that's generally true for younger men. Once you're above 60, those leydig cells that produce testosterone just aren't as responsive as we need them to be.

          The problem all goes back to mitochondria. The smooth endoplasmic reticulum is responsible for converting upstream hormones like pregnenolone into various andro metabolites that break down into testosterone, but the mitochondria are all dysfunctional which is essentially a broken chain in this process.

          The current crop of peptide drugs do help energize existing mitochondria and even regrow new ones, but they are essentially the first gen and aren't effective enough to replace and regrow enough to be effective in this process for seniors who have a lot of mitochondria dysfunction. We do see increases in testosterone from using these drugs, however it's generally in younger people and/or only a small amount.

          When this process is refined and we get 2nd/3rd gen drugs that do this effectively, replacing testosterone won't even be necessary any more for most people, because the mitochondria will be put back to work again and this process will holistically work again.

          J 1 Reply Last reply
          0
          • J Offline
            J Offline
            jackiee
            wrote on last edited by
            #25

            He's going to the doctor Wednesday!

            N 1 Reply Last reply
            1
            • J jackiee

              He's going to the doctor Wednesday!

              N Offline
              N Offline
              Neil McCauley
              wrote on last edited by
              #26

              @jackiew1 said:

              He's going to the doctor Wednesday!

              Excellent. Many who run into issues getting a TRT script from a general practitioner are often younger men. While I can sympathize with them, I can also understand the doctors point of view, I wouldn't be comfortable handing out scripts for test to random 25 year old either. Many have poor lifestyle, sleep, nutrition issues as well as histories with AAS usage.

              I suspect your hubby at his age won't have any problems getting a script. There are pros and cons to going this way - you're going to save a ton of money not going to a TRT clinic.

              The cons are you're not going to get a high level of knowledge/database of information from your GP. If you know how to navigate the internet/message boards/A.I. you can self manage and direct your own TRT care and use your doctor as a vehicle for getting scripts/labs/ancillaries. Many online end up going this route. Most who go the TRT clinic route are fairly independently wealthy and don't mind paying the $$$ to offload this process.

              1 Reply Last reply
              0
              • J Offline
                J Offline
                jackiee
                wrote on last edited by
                #27

                Agreed. If it doesn't work out, we will find a clinic. But I think we can piece together enough nuggets of info to get what he needs from the doctor. Like I said, I am fairly comfortable with what I know about women's hormones and I optimize all of my levels, not just go by what they say is "good". Now I am diving into men's!

                1 Reply Last reply
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                • quicksilver80Q Offline
                  quicksilver80Q Offline
                  quicksilver80
                  wrote on last edited by
                  #28

                  My quoting doesnt work any more oh well. @neilmccauley what burns my ass about gp or pcp is theyll say in the same mouth full these younger men have a generational downward falling lower test levels but disuade against using test because eventually its a life time commitment. But we know stuff like enclomiphene works for us younger people. Has little to low side effects. And can do the job. But refuse that too! Modern medicine is no further away from labotomies and evil spirits in your blood. Next they'll give you a oatmeal enema and call that progress. Thanks kellog haha

                  1 Reply Last reply
                  1
                  • P Offline
                    P Offline
                    Paradox
                    wrote on last edited by
                    #29

                    My rat is also feeling depleted after 1.5mo of R and starts strength training this week. MOTS-C is in the freezer but I’m reading wildly varying dosing from .5mg/daily to 5mg twice a week. Thoughts on where to start and end up? His work schedule involves traveling for 1 week every other week which currently makes it impossible to research on those weeks.

                    J 1 Reply Last reply
                    0
                    • J Offline
                      J Offline
                      jackiee
                      wrote on last edited by
                      #30

                      My husband had his bloodwork done this morning!

                      1 Reply Last reply
                      0
                      • P Paradox

                        My rat is also feeling depleted after 1.5mo of R and starts strength training this week. MOTS-C is in the freezer but I’m reading wildly varying dosing from .5mg/daily to 5mg twice a week. Thoughts on where to start and end up? His work schedule involves traveling for 1 week every other week which currently makes it impossible to research on those weeks.

                        J Offline
                        J Offline
                        jackiee
                        wrote on last edited by
                        #31

                        @Paradox said:

                        My rat is also feeling depleted after 1.5mo of R and starts strength training this week. MOTS-C is in the freezer but I’m reading wildly varying dosing from .5mg/daily to 5mg twice a week. Thoughts on where to start and end up? His work schedule involves traveling for 1 week every other week which currently makes it impossible to research on those weeks.

                        When I did MOTS-c I started at 5mg week, split into 3 injections, to test for any reactions. After a few weeks I went to 10mg a week, split into 3 injections

                        1 Reply Last reply
                        0
                        • N Neil McCauley

                          @brandenscheidecker said:

                          hell no give him something that works lol once a week IM will change his life.

                          At his age of 67, absolutely. Going from very low T to pinning 100mg/week and pushing your T into the 600 to 900 range will be a drastic improvement in energy and overall quality of life. Expect fat loss, muscle gain, improvements in sleep, blood pressure, and glucose measurements as well. There is a reason why TRT is so popular.

                          Many go on TRT way to early in life when lifestyle changes can improve T levels drastically. However that's generally true for younger men. Once you're above 60, those leydig cells that produce testosterone just aren't as responsive as we need them to be.

                          The problem all goes back to mitochondria. The smooth endoplasmic reticulum is responsible for converting upstream hormones like pregnenolone into various andro metabolites that break down into testosterone, but the mitochondria are all dysfunctional which is essentially a broken chain in this process.

                          The current crop of peptide drugs do help energize existing mitochondria and even regrow new ones, but they are essentially the first gen and aren't effective enough to replace and regrow enough to be effective in this process for seniors who have a lot of mitochondria dysfunction. We do see increases in testosterone from using these drugs, however it's generally in younger people and/or only a small amount.

                          When this process is refined and we get 2nd/3rd gen drugs that do this effectively, replacing testosterone won't even be necessary any more for most people, because the mitochondria will be put back to work again and this process will holistically work again.

                          J Offline
                          J Offline
                          jackiee
                          wrote on last edited by
                          #32

                          @Neil-McCauley said:

                          @brandenscheidecker said:

                          hell no give him something that works lol once a week IM will change his life.

                          At his age of 67, absolutely. Going from very low T to pinning 100mg/week and pushing your T into the 600 to 900 range will be a drastic improvement in energy and overall quality of life. Expect fat loss, muscle gain, improvements in sleep, blood pressure, and glucose measurements as well. There is a reason why TRT is so popular.

                          Many go on TRT way to early in life when lifestyle changes can improve T levels drastically. However that's generally true for younger men. Once you're above 60, those leydig cells that produce testosterone just aren't as responsive as we need them to be.

                          The problem all goes back to mitochondria. The smooth endoplasmic reticulum is responsible for converting upstream hormones like pregnenolone into various andro metabolites that break down into testosterone, but the mitochondria are all dysfunctional which is essentially a broken chain in this process.

                          The current crop of peptide drugs do help energize existing mitochondria and even regrow new ones, but they are essentially the first gen and aren't effective enough to replace and regrow enough to be effective in this process for seniors who have a lot of mitochondria dysfunction. We do see increases in testosterone from using these drugs, however it's generally in younger people and/or only a small amount.

                          When this process is refined and we get 2nd/3rd gen drugs that do this effectively, replacing testosterone won't even be necessary any more for most people, because the mitochondria will be put back to work again and this process will holistically work again.

                          We got his testosterone level. It was 442. Now, to
                          Convince the Doctor he heeds 600-900

                          N 1 Reply Last reply
                          0
                          • J jackiee

                            @Neil-McCauley said:

                            @brandenscheidecker said:

                            hell no give him something that works lol once a week IM will change his life.

                            At his age of 67, absolutely. Going from very low T to pinning 100mg/week and pushing your T into the 600 to 900 range will be a drastic improvement in energy and overall quality of life. Expect fat loss, muscle gain, improvements in sleep, blood pressure, and glucose measurements as well. There is a reason why TRT is so popular.

                            Many go on TRT way to early in life when lifestyle changes can improve T levels drastically. However that's generally true for younger men. Once you're above 60, those leydig cells that produce testosterone just aren't as responsive as we need them to be.

                            The problem all goes back to mitochondria. The smooth endoplasmic reticulum is responsible for converting upstream hormones like pregnenolone into various andro metabolites that break down into testosterone, but the mitochondria are all dysfunctional which is essentially a broken chain in this process.

                            The current crop of peptide drugs do help energize existing mitochondria and even regrow new ones, but they are essentially the first gen and aren't effective enough to replace and regrow enough to be effective in this process for seniors who have a lot of mitochondria dysfunction. We do see increases in testosterone from using these drugs, however it's generally in younger people and/or only a small amount.

                            When this process is refined and we get 2nd/3rd gen drugs that do this effectively, replacing testosterone won't even be necessary any more for most people, because the mitochondria will be put back to work again and this process will holistically work again.

                            We got his testosterone level. It was 442. Now, to
                            Convince the Doctor he heeds 600-900

                            N Offline
                            N Offline
                            Neil McCauley
                            wrote on last edited by Neil McCauley
                            #33

                            @jackiew1 said:

                            .

                            We got his testosterone level. It was 442. Now, to
                            Convince the Doctor he heeds 600-900

                            Surprisingly not bad for his age. What was his IGF-1? Did they test DHEA?

                            1 Reply Last reply
                            0
                            • R Online
                              R Online
                              ResearchCat
                              wrote on last edited by
                              #34

                              Just seeing this thread today. Good discussion. Thanks! I am 58, last T test was 399, which is bottom of ‘normal’. Not really what I want to talk about here. I am specifically not interested in TRT unless I get a sign that it is a problem, which it doesn’t seem to be. I could just be an idiot.

                              What I want to talk about is how completely useless most PCP’s and the the medical industrial complex is. I have been saying for decades - partly of self-delusion and partly because it is the only way to describe it - that I am an operational athlete(yeah, I stole that from the old Teams guys). I am going to keep lifting, fighting, moving, etc. Your job is to treat me so I can continue. But that isn’t what doctors do. Doctors keep sick people alive. They don’t help healthy people optimize. If you find a doctor who does this (probably why we all fanboy/girl over Dr. Froeze) never let them go.

                              I am going through one of those periods where I see a bunch of doctors for various things and it is remarkable that you can go to your PCP, an ortho, and other people with your body bruised black from your spine to your ankle and have them remark that it must be quite painful.

                              Anyway, MOTS-C is a great addition to your stack for energy, particularly increasing exercise capacity.

                              Please set a funny and sarcastic signature line. It brings me joy. Thank you for your attention in this matter.

                              C 1 Reply Last reply
                              2
                              • R ResearchCat

                                Just seeing this thread today. Good discussion. Thanks! I am 58, last T test was 399, which is bottom of ‘normal’. Not really what I want to talk about here. I am specifically not interested in TRT unless I get a sign that it is a problem, which it doesn’t seem to be. I could just be an idiot.

                                What I want to talk about is how completely useless most PCP’s and the the medical industrial complex is. I have been saying for decades - partly of self-delusion and partly because it is the only way to describe it - that I am an operational athlete(yeah, I stole that from the old Teams guys). I am going to keep lifting, fighting, moving, etc. Your job is to treat me so I can continue. But that isn’t what doctors do. Doctors keep sick people alive. They don’t help healthy people optimize. If you find a doctor who does this (probably why we all fanboy/girl over Dr. Froeze) never let them go.

                                I am going through one of those periods where I see a bunch of doctors for various things and it is remarkable that you can go to your PCP, an ortho, and other people with your body bruised black from your spine to your ankle and have them remark that it must be quite painful.

                                Anyway, MOTS-C is a great addition to your stack for energy, particularly increasing exercise capacity.

                                C Offline
                                C Offline
                                Commander
                                wrote on last edited by
                                #35

                                @ResearchCat

                                If you don’t want to do TRT, HCG is a great alternative and works great with MOTS-C.
                                Just food for thought

                                Please excuse my typos. Small Phone & Bad Eyes

                                gym.ratG 1 Reply Last reply
                                1
                                • J Offline
                                  J Offline
                                  jackiee
                                  wrote last edited by
                                  #36

                                  Now that I know his test isn’t completely tanked, he will do SS31 and then MOTS-c.

                                  J E 2 Replies Last reply
                                  1
                                  • J jackiee

                                    Now that I know his test isn’t completely tanked, he will do SS31 and then MOTS-c.

                                    J Offline
                                    J Offline
                                    josephrudy
                                    wrote last edited by
                                    #37

                                    @jackiew1

                                    1 Reply Last reply
                                    0
                                    • C Commander

                                      @ResearchCat

                                      If you don’t want to do TRT, HCG is a great alternative and works great with MOTS-C.
                                      Just food for thought

                                      gym.ratG Offline
                                      gym.ratG Offline
                                      gym.rat
                                      wrote last edited by
                                      #38

                                      @Commander My understanding of HCG is that its a great support tool if you are on TRT. If you're not on TRT, I would look at Kisspeptin personally. Maybe even Testagen or stack Testagen with Kisspeptin. The thing with Testagen is that I have anecdotal evidence on both sides of the spectrum and nothing in the middle. That always leaves me suspicious.

                                      Data collector for https://peptideprotocols.app/

                                      1 Reply Last reply
                                      0
                                      • EXTROPIANE Away
                                        EXTROPIANE Away
                                        EXTROPIAN
                                        wrote last edited by EXTROPIAN
                                        #39

                                        Yes run MOTSC, NAD+ and SS-31. You can also suppliment Co Q10 and Methylin blue. My daily go to. As soon as he is back on his feet and wants to level up def add 5amino 1mq + AOD or Slu-pp-322 on the stack. Believe or not, even Semax has given me a boost along a double latte.

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                                        0
                                        • J jackiee

                                          Now that I know his test isn’t completely tanked, he will do SS31 and then MOTS-c.

                                          E Online
                                          E Online
                                          Eleanor
                                          wrote last edited by
                                          #40

                                          @jackiee said:

                                          Now that I know his test isn’t completely tanked, he will do SS31 and then MOTS-c.

                                          And that's what I'm starting come Labor Day weekend and also NAD+ buf. I'll be a month done with Pinealon and Epitalon.

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