Internal Logan's Run

[Stan Douglas]

FOXO4-DRI
5 day cycle: 10mg-off-5mg-off-final 5mg
Planning on repeating twice a year

What is your procedure and how does one even test for results?

[MacLeeezy]

@Stan-Douglas I’m going to start this Friday, and do an almost identical protocol with a grand total of 30mg. For funsies, I had my testosterone checked yesterday and I’m going to check it again in 6-8 weeks. In the mice studies it nearly doubled the test in old mice. Besides hair fullness and the potential to slow down graying hair I’m personally not sure how to test results.

According to Grok:
Practical Testing Approaches
Here are common methods users and clinicians in longevity contexts use or discuss:

1. Blood Biomarkers (Most Accessible):
   • Inflammation/SASP markers: hs-CRP, IL-6, TNF-α, IL-1β. Senolytics often aim to lower chronic “inflammaging.”
   • Senescence-related: p16^INK4a expression in peripheral blood T-cells (emerging biomarker), GDF-15, osteopontin, or other SASP factors. Some labs/research settings measure these. 
   • Hormones: Total/free testosterone (mouse data showed improvements in aged testes via reduced local senescence). Also consider IGF-1 or others.
   • General panels: Comprehensive metabolic panel, liver/kidney function (e.g., AST, creatinine), oxidative stress markers.
   • Timing: Baseline before a cycle, then 2–4 weeks after, and possibly 1–3 months later. Effects may take weeks to months to appear.

[hunt_ak]

I’m going to follow this protocol/stack according to some other info I found elsewhere. That said, I’ll subscribe to the ‘blood in blood out’ mantra of before/after bloodwork before I start.

Planning on doing this mid-month. The Fox is supposed to really make you feel poorly for a bit from what I gather

[MacLeeezy]

Just wanted to share. I tested my natural testosterone before running fox04dri and again a month after cycle and my natural testosterone improved 200 points. Was it the fox or was I already trending in that direction? Not sure. But I can say that I for sure added 200pts prior to the fox cycle (between feb and June)by losing 65lbs on Reta,tesa, good diet, and 5 day a week heavy weight training. So Feb to now, I’m up over 400pts total. I plan to give kisspeptin, and testagen a try and test again. Then maybe low dose enclomaphene to see if I can squeeze a little more out if need be.

[Stan Douglas]

I have no experience with kisspeptin, testagen or enclomaphene.
My natural test has been 800 for decades since I've been having it tested.
The last Rythm test came back in the 900s, I assume it was the CJC +Ip cycle I was on at the time.

One tweek I'll make with my next Foxhunt is keeping the dosage the same each day. Just do a third of the vial.