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Peptide Critic Community

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  1. Randy the Rats Research Forum
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  3. GHK-Cu/KPV protocol
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GHK-Cu/KPV protocol

Scheduled Pinned Locked Moved Peptide Discussion
ghk-cukpv
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  • R Offline
    R Offline
    RagnatLothbrok
    wrote last edited by RagnatLothbrok
    #1

    So very soon, I’m starting my wife on GHK-Cu 50mg and KPV 10mg (separately, not a blend) for her skin. She’s always dealing with skin issues like pimples, redness, and breakouts. What protocols have you guys used before? And at what you time do you usually do it? I’ve seen people running them daily or every other day. Lmk your thoughts!

    Also, do you pin on your belly or is there a better way to go with this?

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    • gym.ratG Offline
      gym.ratG Offline
      gym.rat
      wrote last edited by
      #2

      Belly or upper outer glute is fine. Anywhere really.

      Is this a blend? What is the ratio?

      KPV
      Dose: 200 to 400 mcg once daily
      Duration: 4 to 8 weeks
      Administration: Subq
      Use case: Systemic inflammation, autoimmune support

      GHK
      Dose: 5x weekly or daily; 1mg to 3mg is the most common and I think 3mg is the sweet spot for results and sting tolerance. Some do high doses (5mg+). 6 weeks seems to be the accumulation period where you really start to notice results.
      Duration: 6 - 8 weeks on; same off
      Administration: Subq

      R 1 Reply Last reply
      -1
      • gym.ratG gym.rat

        Belly or upper outer glute is fine. Anywhere really.

        Is this a blend? What is the ratio?

        KPV
        Dose: 200 to 400 mcg once daily
        Duration: 4 to 8 weeks
        Administration: Subq
        Use case: Systemic inflammation, autoimmune support

        GHK
        Dose: 5x weekly or daily; 1mg to 3mg is the most common and I think 3mg is the sweet spot for results and sting tolerance. Some do high doses (5mg+). 6 weeks seems to be the accumulation period where you really start to notice results.
        Duration: 6 - 8 weeks on; same off
        Administration: Subq

        R Offline
        R Offline
        RagnatLothbrok
        wrote last edited by RagnatLothbrok
        #3

        @gym.rat thanks for the question, I got them separately so I can have more control with the dosing. And thanks, that’s what I’ve been seeing the most with these. I’ll start with the lowest possible and see from there! I’ll also reconstitute with 3ml of bac water hoping it doesn’t sting her

        gym.ratG 1 Reply Last reply
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        • R RagnatLothbrok

          @gym.rat thanks for the question, I got them separately so I can have more control with the dosing. And thanks, that’s what I’ve been seeing the most with these. I’ll start with the lowest possible and see from there! I’ll also reconstitute with 3ml of bac water hoping it doesn’t sting her

          gym.ratG Offline
          gym.ratG Offline
          gym.rat
          wrote last edited by
          #4

          @RagnatLothbrok My female rat does GHK in the glutes (3ml bac) and has about a 2-3 on the pain scale in her glute. She says its fine and that buffered NAD is worse (4-5 on pain scale). Unbuffered NAD on the other hand was rated an 8 just to give you a full comparison.

          KPV on the other hand is a nothing burger. Similar to Reta which is the easiest pin I've ever done to date. A fat ZERO on the pain scale.

          R 1 Reply Last reply
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          • gym.ratG gym.rat

            @RagnatLothbrok My female rat does GHK in the glutes (3ml bac) and has about a 2-3 on the pain scale in her glute. She says its fine and that buffered NAD is worse (4-5 on pain scale). Unbuffered NAD on the other hand was rated an 8 just to give you a full comparison.

            KPV on the other hand is a nothing burger. Similar to Reta which is the easiest pin I've ever done to date. A fat ZERO on the pain scale.

            R Offline
            R Offline
            RagnatLothbrok
            wrote last edited by
            #5

            @gym.rat

            @gym.rat I had no idea NAD was painful to pin. Thanks for this! I’m going to be combining in the same syringe both ghk-cu and kpv, Let’s see how it goes for my female rat 😁

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            • E Offline
              E Offline
              emkay
              wrote last edited by emkay
              #6

              I started both on RS recently, kpv about 2 weeks ahead of ghk so I could gauge tolerance. Kpv helped a lot with dermatitis rashes from autoimmune flare-ups, but about 10 days in RS started having dizzy spells and had to pause. Ghk tolerance has been fine, occasionally pokes are "spicy" but nothing extreme.

              Kpv was 100 mcg twice a day, ghkcu I believe is up to 1 mg once a day, 5x a week. I use glutes for both.

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              • WisGal64W Online
                WisGal64W Online
                WisGal64
                wrote last edited by
                #7

                @emkay are you getting enough H20 on the day to day? with GHK and KPV being an anti-inflammatory, plus anything else you may be taking, could be an electrolyte imbalance.

                “Currently in a committed relationship with my plateau. Waiting for my receptor reset to file for divorce”

                E 1 Reply Last reply
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                • R Offline
                  R Offline
                  ResearchCat
                  wrote last edited by
                  #8

                  @ragnatlothbrok The difference between GHK and NAD wrt injection pain is that when GHK burns, it burns after injection and can last hours to days. NAD burns for an instant and is done. In my experience, injecting slower helps with both. I’ve been researching Klow for a while and don’t have any burn with it.

                  Please set a funny and sarcastic signature line. It brings me joy. Thank you for your attention in this matter.

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                  • WisGal64W WisGal64

                    @emkay are you getting enough H20 on the day to day? with GHK and KPV being an anti-inflammatory, plus anything else you may be taking, could be an electrolyte imbalance.

                    E Offline
                    E Offline
                    emkay
                    wrote last edited by
                    #9

                    @WisGal64 oh yes, I drink a lot of Gatorade and water. Part of my autoimmune mess is adrenal insufficiency/Addison's so I have a very strong habit for hydration. BP tends to run on the low side as is. Considered a herx reaction as a possibility, but I'm also extremely med sensitive in general, so it's hard to say. Dizzy spells stopped within 48 hours of discontinuing so it was a short term issue at least.

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