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  3. Odd comments on Peptide Crafters ara-290 COA - what's this?
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Odd comments on Peptide Crafters ara-290 COA - what's this?

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  • ? Offline
    ? Offline
    A Former User
    wrote on last edited by
    #1

    There are comments on a COA for ara-290 on peptide crafters that I haven't seen before. A quick google makes me think this batch may be dangerous or suspect without identifying exactly WHAT caused the other peak. Anyone know for sure what this means? https://peptidecrafters.com/wp-content/uploads/2026/03/HPLC-ARA-290-16-mg-PC-G1-AR16-scaled.png

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    • vpeptidesV Offline
      vpeptidesV Offline
      vpeptides
      wrote on last edited by
      #2

      This HPLC COA is also from the same batch, 2 months later.

      attentiion is all you need

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      • vpeptidesV Offline
        vpeptidesV Offline
        vpeptides
        wrote on last edited by vpeptides
        #3

        My research using AI concluded that mentioned "unretained peak" is something negligible and likely is a moisture or salt. I checked with Peptide Crafters to confirm they run counter-ion step to make it an acetate salt, not TFA. I actually coincidentally purchased the same batch yesterday from them.

        attentiion is all you need

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        • vpeptidesV vpeptides

          My research using AI concluded that mentioned "unretained peak" is something negligible and likely is a moisture or salt. I checked with Peptide Crafters to confirm they run counter-ion step to make it an acetate salt, not TFA. I actually coincidentally purchased the same batch yesterday from them.

          ? Offline
          ? Offline
          A Former User
          wrote on last edited by
          #4

          @vpeptides So are you saying Peptide Crafters claimed they manufactured this? That's sketch....

          vpeptidesV 1 Reply Last reply
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          • ? A Former User

            @vpeptides So are you saying Peptide Crafters claimed they manufactured this? That's sketch....

            vpeptidesV Offline
            vpeptidesV Offline
            vpeptides
            wrote on last edited by vpeptides
            #5

            @jamiegallien I can't say for sure but my understanding is that the companies run lyophilization phase themselves. They may receive the synthesized product as TFA salt, then run counter-ion process to replace TFA salts with acetate salt, then lyophilize.
            Or they receive it already as acetate salt.
            But this is my speculation, and they are not very clear and open on what they do and where they do it.
            This was the response:
            Our products are supplied as acetate salts, meaning acetate is the specified counter-ion for the finished product. We do not supply our products as TFA salts.

            attentiion is all you need

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