Where to get a vial of Sodium Bicarbonate to buffer NAD+?
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I pH tested my big vial of NAD+ and sure enough, pH of 4 when buffer should be right around 7. Looks like titrating it some injectable sodium bicarbonate is a valid fix but I need to find some that doesn’t require a prescription or medical license to order. Anyone got a line on a vial?
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I looked around, but I don't think you can do this with any real confidence to be honest. Bite the bullet and finish off the vial or go out and buy some buffered NAD+
Injectable (sterile) sodium bicarbonate 8.4% is a prescription/pharmaceutical-grade product (e.g., Hospira/Pfizer, Fresenius, etc.), typically indicated for treating metabolic acidosis. It's not something commonly sold over-the-counter or without restrictions for research/DIY use due to its potency, hypertonicity, and need for precise handling.
Better Alternatives for Buffering NAD+
Titrating acidic NAD+ (pH ~4) toward neutral (~7) with bicarb can help reduce injection pain/burning, but this needs extreme caution—over-alkalizing, CO2 production, precipitation, or incompatibility with NAD+ stability are real risks. Small, slow additions while monitoring pH are key; do this in small test batches.
Safer/more practical options many use for NAD+:Data collector for https://peptideprotocols.app/
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I looked around, but I don't think you can do this with any real confidence to be honest. Bite the bullet and finish off the vial or go out and buy some buffered NAD+
Injectable (sterile) sodium bicarbonate 8.4% is a prescription/pharmaceutical-grade product (e.g., Hospira/Pfizer, Fresenius, etc.), typically indicated for treating metabolic acidosis. It's not something commonly sold over-the-counter or without restrictions for research/DIY use due to its potency, hypertonicity, and need for precise handling.
Better Alternatives for Buffering NAD+
Titrating acidic NAD+ (pH ~4) toward neutral (~7) with bicarb can help reduce injection pain/burning, but this needs extreme caution—over-alkalizing, CO2 production, precipitation, or incompatibility with NAD+ stability are real risks. Small, slow additions while monitoring pH are key; do this in small test batches.
Safer/more practical options many use for NAD+:Injectable (sterile) sodium bicarbonate 8.4% is a prescription/pharmaceutical-grade product (e.g., Hospira/Pfizer, Fresenius, etc.), typically indicated for treating metabolic acidosis. It's not something commonly sold over-the-counter or without restrictions for research/DIY use due to its potency, hypertonicity, and need for precise handling.
Yeah, that's the conclusion I came to as well. I've actually got access to some quality lab gear for reading pH through work but if it's more trouble than it's worth, oh well. So goes the wild wild west. I'll do a test pin of a few units and load it into a nasal spray if it's too spicy. Thanks for weighing in on my dumb noob idea, I'm smart but not THAT smart...
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Injectable (sterile) sodium bicarbonate 8.4% is a prescription/pharmaceutical-grade product (e.g., Hospira/Pfizer, Fresenius, etc.), typically indicated for treating metabolic acidosis. It's not something commonly sold over-the-counter or without restrictions for research/DIY use due to its potency, hypertonicity, and need for precise handling.
Yeah, that's the conclusion I came to as well. I've actually got access to some quality lab gear for reading pH through work but if it's more trouble than it's worth, oh well. So goes the wild wild west. I'll do a test pin of a few units and load it into a nasal spray if it's too spicy. Thanks for weighing in on my dumb noob idea, I'm smart but not THAT smart...
@SwollStreetBets Yeah I'm not that smart either. My first ever pin of NAD+ was non buffered and it was hot salsa spicy. Hated it. Then learned that buffered NAD+ was a thing and only some vendors carry it (hello Glacier Aminos: use code "protocol10"). The other thing I've learned as I read / research way too many hours a day is that buffered NAD+ degrades slower and based on the rats in my house feels stronger. So take that as you will.
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Is BAC sodium chloride a possible solution? https://peptidetest.com/products/pfizer-hospira-bacteriostatic-sodium-chloride-for-injection-30-ml
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@swollstreetbets Don't mess with that bicarb BS if you don't know EXACTLY what you're doing!
S1research.net Has 1000mg NAD+ BUFFERED for $55 single vial, and less for kits.
If I had to give up all peps except one, NAD+ BUF if the one I'd keep. It has saved me, it really has. -
Injectable (sterile) sodium bicarbonate 8.4% is a prescription/pharmaceutical-grade product (e.g., Hospira/Pfizer, Fresenius, etc.), typically indicated for treating metabolic acidosis. It's not something commonly sold over-the-counter or without restrictions for research/DIY use due to its potency, hypertonicity, and need for precise handling.
Yeah, that's the conclusion I came to as well. I've actually got access to some quality lab gear for reading pH through work but if it's more trouble than it's worth, oh well. So goes the wild wild west. I'll do a test pin of a few units and load it into a nasal spray if it's too spicy. Thanks for weighing in on my dumb noob idea, I'm smart but not THAT smart...
@SwollStreetBets If it's that spicy, just do it IM.
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