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Low Dose Tadalafil

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  • ResearchCatR ResearchCat

    Will do. Probably a month of so away. Not in a huge hurry. Want to see my latest T levels, what the Cardiologist says, then I’ll decide what to do.

    I figured that some of you folks are probably also obsessive optimizers and might have experience with this. I am waiting for Pete to chime in and tell me i need to crush precisely 1.7 mg and snort it through my right nostril only for maximum effect. 😉

    S Offline
    S Offline
    Stones67
    wrote last edited by
    #11

    @ResearchCat
    LOL. He would too if he thought it would give him a 0.015% improvement in effect! You're doing it the right way.

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    • ResearchCatR ResearchCat

      Is anybody taking low dose tadalafil? It is not a peptide, but it recently came to my attention for its off-label use for cardiovascular health, muscle building improvements, exercise capacity, and prostate health. It looks like many online T providers pair it with enclomiphene. Limited side effects, however you should not take it if you use nitroglycerine for your heart as together they might kill you.

      A common protocol is 2.5mg or 5mg per day.

      I am looking into it, asking my cardiologist about risk factors and concerns, and thinking I might give it a try with or without enclomiphene depending on my upcoming lab results.

      This originally came to my attention via Huberman on the Modern Wisdom podcast, where he was recommending it to most healthy men over 40 for its protective and exercise benefit, noting the benefits of a healthier(smaller) prostate and being able to brick up instantly as nice to haves.

      judgetooJ Offline
      judgetooJ Offline
      judgetoo
      wrote last edited by
      #12

      @ResearchCat I'm on 5mg daily dose. Been on it for years. I take it for prostate and cardiovascular health. I haven't had any issues with it other than an occasional flushing and a stuffy nose, but it's not anything major. I'm not taking enclomiphene.

      Was there something specific that you were curious about?

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      • U Offline
        U Offline
        ursus
        wrote last edited by
        #13

        I’ve use in 2.5mg to 5mg as a pre workout it can offer some good pumps (not an intentional pun).

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        • J Offline
          J Offline
          justalittleprick
          wrote last edited by
          #14

          I started 2.5mg about a month ago and then increased to 5mg.

          One thing to note: Do NOT take a pre-workout that has L-citrulline or nitrates in it. It can cause your blood pressure to drop too much, which can be very dangerous.

          I like my pre-workout and I had to totally stop taking it b/c it contained L-citrulline. The first time I took a 2.5mg and then used my pre-workout, I felt a blood pressure drop while doing squats. No bueno.

          I drink a Celcius now for the caffeine.

          Effects:

          I have nice vascularity in my forearms and biceps and get a good pump at the gym. I feel like my blood pressure in a really good state and the always on dose is good for the intended benefits.

          I have blood labs tomorrow, so I'll look for other positive endothelial signs.

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          • ResearchCatR Offline
            ResearchCatR Offline
            ResearchCat
            wrote last edited by
            #15

            @judgetoo I was just curious if folks are using it, whether it is working for the intended goals, any issues or side effects, etc. Since many of you are researching similar protocols to mine and seeking similar goals(Immortality + Glory), you might have insights into things that could help and things to avoid.

            Yeah, well, I’m just here for the research, man. - The Dude

            If I haven’t liked your post, no offense. I have exceeded my daily allowance.

            C 1 Reply Last reply
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            • vpepsV Offline
              vpepsV Offline
              vpeps
              wrote last edited by vpeps
              #16

              It is easy to get a prescription for tadalafil from any general practitioner, just hint at ED 🙂 nobody will be doing tests to check your complain. It's a very cheap generic drug.
              It is researched for general longevity (there is an association in the large database in British research), lowering pressure, also increasing NO levels in blood indirectly - behaving as upregulator of eNOS expression.
              But there are possible side effects like blurred vision, stuffed nose, etc. Ah, and of course night erections like in a teenager.

              attentiion is all you need

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              • NewenoughN Online
                NewenoughN Online
                Newenough
                wrote last edited by
                #17

                Damn, guess that "you'll go blind" was true then!

                1 Reply Last reply
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                • B Offline
                  B Offline
                  brandenscheidecker
                  wrote last edited by
                  #18

                  just saw some on grey 50mg, holy cow!

                  1 Reply Last reply
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                  • ResearchCatR Offline
                    ResearchCatR Offline
                    ResearchCat
                    wrote last edited by
                    #19

                    That must be the hookers and blow package.

                    Yeah, well, I’m just here for the research, man. - The Dude

                    If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                    Snake PepskinS 1 Reply Last reply
                    4
                    • ResearchCatR ResearchCat

                      @judgetoo I was just curious if folks are using it, whether it is working for the intended goals, any issues or side effects, etc. Since many of you are researching similar protocols to mine and seeking similar goals(Immortality + Glory), you might have insights into things that could help and things to avoid.

                      C Offline
                      C Offline
                      CapmanCrunch
                      wrote last edited by
                      #20

                      @ResearchCat
                      I have been using 5mg per day for about 6 months now and I like it a lot.
                      Increased blood flow and pumps when working out. The plumping of the nether regions calms down significantly after the first week or so. I generally do not like to take medications like this, but this one has been good with no side effects.

                      1 Reply Last reply
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                      • ResearchCatR ResearchCat

                        That must be the hookers and blow package.

                        Snake PepskinS Offline
                        Snake PepskinS Offline
                        Snake Pepskin
                        wrote last edited by
                        #21

                        @ResearchCat

                        That’s the “Two hookers and an 8ball” special.

                        “Knowledge is the ultimate power.
                        It’s not what you know that defines you, it’s that which you share that defines you.”

                        1 Reply Last reply
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                        • vpepsV Offline
                          vpepsV Offline
                          vpeps
                          wrote last edited by vpeps
                          #22

                          I get a vision loss side effect from it, even from 1/3 of 2.5mg dose. It starts soon after taking a dose, expressed as inability to see small details, like when reading the text or seeing at a distance. It goes away after a day or two. I tried to integrate 1/3 or 1/2 of a 2.5mg pill as a daily protocol to slightly lower my blood pressure, and hoping it lowers the inflammation of the vessels by relaxing them (because inflammation of the vessels correlates with atherosclerosis), but it is difficult to live with an impaired eyesight like this. I don't wear the glasses but I might have to if I go this way.

                          attentiion is all you need

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                          • ResearchCatR Offline
                            ResearchCatR Offline
                            ResearchCat
                            wrote last edited by
                            #23

                            @vpeptides Yeah, given the goal of improving overall health, I’d think that side effects like that would likely result in my not using them either. I am grudgingly taking some new medications because the risk/reward balance is too high not to, but managing side effects is very important to me. So far, so good.

                            Yeah, well, I’m just here for the research, man. - The Dude

                            If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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                            • ResearchCatR Offline
                              ResearchCatR Offline
                              ResearchCat
                              wrote last edited by
                              #24

                              How Timely! https://youtu.be/dLqPxKeYF04?is=fpkncUAr9kQFBTub Urologist on using ED meds for overall health.

                              Yeah, well, I’m just here for the research, man. - The Dude

                              If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                              1 Reply Last reply
                              0
                              • G Offline
                                G Offline
                                greenman
                                wrote last edited by
                                #25

                                I started a 5mg/daily dose a couple of weeks ago. I don't know if I can talk about overall health benefits but I will say I have had the strongest and most frequent NRB's in years, and this is not a place I have been lacking. It's awesome, but I will say that the climax itself is about 20% less euphoric than usual. This is the first time I've ever taken anything like this. My wife is enjoying it.

                                So far my eyes are doing. No lost vision. Though I wouldn't mind if a loss of hearing was a side effect.

                                1 Reply Last reply
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                                • ResearchCatR Offline
                                  ResearchCatR Offline
                                  ResearchCat
                                  wrote last edited by
                                  #26

                                  Had to see a urologist for something else, no problem at all writing me a script for tadalafil. They even gave me a coupon. 🤣 I guess insurance thinks you should only get 5 boners a month.

                                  Anyway, we’ll see what’s up with enclomiphene vs TRT down the road a bit. Since this is a urologist, they really prefer TRT and think enclomiphene is limiting for older men who have limited production to work with.

                                  Yeah, well, I’m just here for the research, man. - The Dude

                                  If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                                  vpepsV 1 Reply Last reply
                                  0
                                  • ResearchCatR ResearchCat

                                    Had to see a urologist for something else, no problem at all writing me a script for tadalafil. They even gave me a coupon. 🤣 I guess insurance thinks you should only get 5 boners a month.

                                    Anyway, we’ll see what’s up with enclomiphene vs TRT down the road a bit. Since this is a urologist, they really prefer TRT and think enclomiphene is limiting for older men who have limited production to work with.

                                    vpepsV Offline
                                    vpepsV Offline
                                    vpeps
                                    wrote last edited by
                                    #27

                                    @ResearchCat it costs like $20 for 90 tablets at Costco or Amazon without any insurance if you have a prescription.

                                    attentiion is all you need

                                    1 Reply Last reply
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