Undissolved flakes + material fused to the vial wall — normal, or a bad vial?
-
Looking for a sanity check from people who've reconstituted more of these than I have.
Product: Kisspeptin-10, 10mg lyophilized vial. Vendor is one this community rates highly. I've spent just under $1K with them and this is the first vial I've had an issue with.
Reconstituted with 3 mL Hospira BAC water, added slowly down the inside of the glass. No shaking.
What happened: most of the cake dissolved, but a substantial chunk stayed stuck to the interior glass wall. Gentle agitation and 20 minutes of sitting didn't move it, so I directed the stream from the syringe at it to knock it loose. Parts of it stayed adhered to the glass even then. Those eventually came off, but they still haven't dissolved. They've been floating for 16 hours now at room temp. The liquid itself is clear — not cloudy, not gelled.
Two questions:
-
Has anyone seen kisspeptin do this? Is visible undissolved material normal for this compound, or is this a bad vial? Anyone recovered one like it, or is it a write-off?
-
I sent the vendor this photo and requested a replacement. Denied — "we are unable to offer replacements or refunds for reconstitution-related concerns, since many of the factors involved occur outside of our control after delivery." Is that the norm elsewhere, or do most vendors reship on something like this?
Not confident enough in it to use, so it's probably a loss either way. Mostly want to know whether my expectations are off.
Regards
-
-
Please name the vendor. It so ridiculous to me that some of these vendors don't want to keep a customer happy. As we all know their margins are incredible on single vial peptides. They replace the vial and keep you happy and ordering from them in the future. They don't and consumers like me will add them to our do not buy from list. So please name the vendor.
To put it in perspective though mine was a slightly different issue, I had purchased about I believe 24vials of AOD 9604 from Instant Peptides. 3 straight vials gelled using Hospira Bac water and their own Acetic Acid. Contacted Chris the owner and he sent replacement AOD 9604 and AA to try out. The new vials reconstituted fine and I figured out the issue was actually their AA. Just using Hospira alone without AA reconned fine. Because Chris did the correct thing to keep me happy, by sending out new vials to try, he kept me as a customer even though I can find cheaper prices elsewhere. And I buy in bulk. Some of these vendors are penny wise and pound foolish.
-
Looking for a sanity check from people who've reconstituted more of these than I have.
Product: Kisspeptin-10, 10mg lyophilized vial. Vendor is one this community rates highly. I've spent just under $1K with them and this is the first vial I've had an issue with.
Reconstituted with 3 mL Hospira BAC water, added slowly down the inside of the glass. No shaking.
What happened: most of the cake dissolved, but a substantial chunk stayed stuck to the interior glass wall. Gentle agitation and 20 minutes of sitting didn't move it, so I directed the stream from the syringe at it to knock it loose. Parts of it stayed adhered to the glass even then. Those eventually came off, but they still haven't dissolved. They've been floating for 16 hours now at room temp. The liquid itself is clear — not cloudy, not gelled.
Two questions:
-
Has anyone seen kisspeptin do this? Is visible undissolved material normal for this compound, or is this a bad vial? Anyone recovered one like it, or is it a write-off?
-
I sent the vendor this photo and requested a replacement. Denied — "we are unable to offer replacements or refunds for reconstitution-related concerns, since many of the factors involved occur outside of our control after delivery." Is that the norm elsewhere, or do most vendors reship on something like this?
Not confident enough in it to use, so it's probably a loss either way. Mostly want to know whether my expectations are off.
Regards
"we are unable to offer replacements or refunds for reconstitution-related concerns, since many of the factors involved occur outside of our control after delivery."
WOW, that is a Vendor I'd cross off my list. Anytime I've had an issue with a product, the vendor was willing to work with me. Sent pics/videos and what I reconned with. Replacements or refund was offered.
-
-
Yes, I was a little surprised they wouldn't send a replacement for a $35 vial... I mean I am seeing posts from vetted grey market vendors issuing credits/replacements for the entire kit for similar issues. Still no change in the solution, not risking my rat for this.
Vendor SouthernAminos, I included a screen shot of their policy so no one has to create an account to view it. No issues with them till this, first time I had to deal with customer service, which is what other negative reviews also mentioned. Researchers be aware of their policy. I don't think an issue with the batch is the problem. Product ships from the same fulfillment address as other vendors and no issues with those ones either. Just customer no-service...
-
Yes, I was a little surprised they wouldn't send a replacement for a $35 vial... I mean I am seeing posts from vetted grey market vendors issuing credits/replacements for the entire kit for similar issues. Still no change in the solution, not risking my rat for this.
Vendor SouthernAminos, I included a screen shot of their policy so no one has to create an account to view it. No issues with them till this, first time I had to deal with customer service, which is what other negative reviews also mentioned. Researchers be aware of their policy. I don't think an issue with the batch is the problem. Product ships from the same fulfillment address as other vendors and no issues with those ones either. Just customer no-service...Yes, I was a little surprised they wouldn't send a replacement for a $35 vial... I mean I am seeing posts from vetted grey market vendors issuing credits/replacements for the entire kit for similar issues. Still no change in the solution, not risking my rat for this.
Vendor SouthernAminos, I included a screen shot of their policy so no one has to create an account to view it. No issues with them till this, first time I had to deal with customer service, which is what other negative reviews also mentioned. Researchers be aware of their policy. I don't think an issue with the batch is the problem. Product ships from the same fulfillment address as other vendors and no issues with those ones either. Just customer no-service...Thank you for naming them. They are already on my do not buy list as I had an issue with them with AOD-9604. If you look up my posts you can see a thread I started about them. They did offer for me too ship it back (at my own expense for a refund) but it was not worth the hassle for me to do so. I simply don't trust them.
Market is saturated with so many vendors, that we can pick and choose who we want to buy from. I imagine with their policy they have lost a customer in you.
Why do you not think it's an issue with the batch? I think that's exactly what the issue is. They sent me two different batches of AOD 9604 but used the same batch # on the bottle. That does not seem right to me and actually concerning. But on their bottles they label the avg mg in each vial. So same batch # but different avg mg?? As you can see in the picture below, the vial on the left looks old and faded compared to the vial on the right. The vial on the right matches the COA while the vial on the left does not match the COA in regards to mass and purity. I discarded 10 vials of the older looking AOD from them

-
Yes, I was a little surprised they wouldn't send a replacement for a $35 vial... I mean I am seeing posts from vetted grey market vendors issuing credits/replacements for the entire kit for similar issues. Still no change in the solution, not risking my rat for this.
Vendor SouthernAminos, I included a screen shot of their policy so no one has to create an account to view it. No issues with them till this, first time I had to deal with customer service, which is what other negative reviews also mentioned. Researchers be aware of their policy. I don't think an issue with the batch is the problem. Product ships from the same fulfillment address as other vendors and no issues with those ones either. Just customer no-service...Thank you for naming them. They are already on my do not buy list as I had an issue with them with AOD-9604. If you look up my posts you can see a thread I started about them. They did offer for me too ship it back (at my own expense for a refund) but it was not worth the hassle for me to do so. I simply don't trust them.
Market is saturated with so many vendors, that we can pick and choose who we want to buy from. I imagine with their policy they have lost a customer in you.
Why do you not think it's an issue with the batch? I think that's exactly what the issue is. They sent me two different batches of AOD 9604 but used the same batch # on the bottle. That does not seem right to me and actually concerning. But on their bottles they label the avg mg in each vial. So same batch # but different avg mg?? As you can see in the picture below, the vial on the left looks old and faded compared to the vial on the right. The vial on the right matches the COA while the vial on the left does not match the COA in regards to mass and purity. I discarded 10 vials of the older looking AOD from them

@denti said:
Market is saturated with so many vendors, that we can pick and choose who we want to buy from. I imagine with their policy they have lost a customer in you.Why do you not think it's an issue with the batch? I think that's exactly what the issue is. They sent me two different batches of AOD 9604 but used the same batch # on the bottle. That does not seem right to me and actually concerning. But on their bottles they label the avg mg in each vial. So same batch # but different avg mg?? As you can see in the picture below, the vial on the left looks old and faded compared to the vial on the right. The vial on the right matches the COA while the vial on the left does not match the COA in regards to mass and purity. I discarded 10 vials of the older looking AOD from them
Yeah, that does seem sketchy — especially from a company that markets itself on quality and testing. Two vials carrying the same lot number but different average mg is the part that would bother me most. Either the lot number is wrong or the fill is inconsistent, and neither is a good answer.
To your question: I'm not saying it isn't a batch issue, just that I can't claim it. This was a test buy, so I only ordered one vial. With an n of 1 I have no way to tell a bad vial from a bad batch. If they'd shipped a replacement, or if I'd bought more, I'd have something to compare against — which is part of why the denial is annoying beyond the $35.
I'm curious what's actually floating in there, but that peptide isn't on Finnrick's free testing list and I'm not paying to test a $35 vial. Might throw it in the freeze dryer just to see whether it comes back as powder. Curiosity... Then it's in the trash.
Either way, that's my last order with them. A company that won't stand behind its product isn't worth the time. The case I opened was closed immediately with no room for rebuttal per their policy.
-
Kisspeptin is one of those temperamental peptides. They sometimes take more BAC to recon than usual, sometimes acetic acid. I’ve seen it before.
BTW AOD is another one that is known to be complex to recon. Some vendors will send dedicated bac with it.
Sorry to say, it might not be on the vendor.
-
This post is deleted!
-
Kisspeptin is one of those temperamental peptides. They sometimes take more BAC to recon than usual, sometimes acetic acid. I’ve seen it before.
BTW AOD is another one that is known to be complex to recon. Some vendors will send dedicated bac with it.
Sorry to say, it might not be on the vendor.
@Snake-Pepskin
Fair point, and appreciated — I hadn't considered acetic acid for kisspeptin. Good to know for next time.Here's why I still lean toward the vial rather than the recon, though: roughly 1/8 of the cake was fused to the glass wall. The other 7/8 dissolved without any trouble. If this were the compound being difficult at my concentration, I'd expect the whole cake to fight me, not for most of it to go in clean and one welded piece to hold out. The floating flakes look like residue from where it was bonded to the glass — translucent, and the two bigger ones drift around like ghosts when you shake it up. Which is admittedly kind of cool.
Diluent was Hospira BAC, day 5 from cracking the seal. Used the same bottle successfully before and after this vial, so I don't think that's the variable either.
My read is that it happened at lyophilization — a cake that partly collapsed or fused to the wall during freeze drying. Storage on the vendor's end is possible too; I'm taking it on trust that it was held properly.
Either way, they refused a replacement, so I won't be ordering from them again.
Hello! It looks like you're interested in this conversation, but you don't have an account yet.
Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.
With your input, this post could be even better 💗
Register Login