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Peptide Critic Community

Peptide Critic Community

  1. Randy the Rats Research Forum
  2. Peptide Discussion
  3. Peptide Negatives: Anything Beyond Injection Site Reactions?
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Peptide Negatives: Anything Beyond Injection Site Reactions?

Scheduled Pinned Locked Moved Peptide Discussion
21 Posts 16 Posters 1.7k Views 2 Watching
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  • brithusB Offline
    brithusB Offline
    brithus
    wrote last edited by brithus
    #12

    Had one subject have a big allergic reaction to MOTS-C. I'm talking a HUGE welt over half the abdomen. Immediately dosed benadryl and used steroid cream on the injection site and had Epi pen ready. Lasted several hours. Did not risk giving to that subject again. Other subject that started at same time with same vial had no reaction. So be careful because anaphylaxis is real and nothing to mess around with!

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    • AmericanchildA Offline
      AmericanchildA Offline
      Americanchild
      wrote last edited by
      #13

      KPV caused me to retain a significant amount of water, so much so that I had to discontinue it. I was gaining about a pound a day while I was on it, despite no change in diet.And within three days of stopping it and taking a lasix, the retained water flushed out of my body and I have had no more issues with fluid retention.

      WisGal64W 1 Reply Last reply
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      • quicksilver80Q Offline
        quicksilver80Q Offline
        quicksilver80
        wrote last edited by
        #14

        Yeah motsc gave me a little red spot that went away in a hour. Ss31 regularly bruised me but found out it was more injections going too deep. Little side note. Unisom sleep gels is usually a higher dose 50mg? of diphenhydramine. In case you need some antihistamines in a pinch.

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        • B Offline
          B Offline
          bangkokiscool
          wrote last edited by
          #15

          SS-31 will also cause increase in eosonophils, a type of WBC.

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          • AmericanchildA Americanchild

            KPV caused me to retain a significant amount of water, so much so that I had to discontinue it. I was gaining about a pound a day while I was on it, despite no change in diet.And within three days of stopping it and taking a lasix, the retained water flushed out of my body and I have had no more issues with fluid retention.

            WisGal64W Offline
            WisGal64W Offline
            WisGal64
            wrote last edited by
            #16

            @Americanchild said:

            KPV caused me to retain a significant amount of water, so much so that I had to discontinue it. I was gaining about a pound a day while I was on it, despite no change in diet.And within three days of stopping it and taking a lasix, the retained water flushed out of my body and I have had no more issues with fluid retention.

            This surprises me but everyone reacts differently.

            “Currently in a committed relationship with my plateau. Waiting for my receptor reset to file for divorce”

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            • E Offline
              E Offline
              Emkay
              wrote last edited by
              #17

              Kpv above 100 mcg still gives me terrible dizziness to the point of blacking out. It helps a ton with certain autoimmune symptoms so I hate to discontinue but I have to keep it very low.

              vpeptidesV 1 Reply Last reply
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              • E Emkay

                Kpv above 100 mcg still gives me terrible dizziness to the point of blacking out. It helps a ton with certain autoimmune symptoms so I hate to discontinue but I have to keep it very low.

                vpeptidesV Online
                vpeptidesV Online
                vpeptides
                wrote last edited by
                #18

                @emkay I've had a bad reaction to one brand of oral KPV, also almost passing out, but tried a different brand and it was fine.

                attentiion is all you need

                E 1 Reply Last reply
                1
                • vpeptidesV vpeptides

                  @emkay I've had a bad reaction to one brand of oral KPV, also almost passing out, but tried a different brand and it was fine.

                  E Offline
                  E Offline
                  Emkay
                  wrote last edited by
                  #19

                  @vpeptides very interesting,! I've only used from EZ so far. I'll have to branch out.

                  vpeptidesV 1 Reply Last reply
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                  • E Emkay

                    @vpeptides very interesting,! I've only used from EZ so far. I'll have to branch out.

                    vpeptidesV Online
                    vpeptidesV Online
                    vpeptides
                    wrote last edited by
                    #20

                    @emkay it could be also the dosage, both pills were labeled 500 mcg, but one of them could've been overfilled.

                    attentiion is all you need

                    1 Reply Last reply
                    1
                    • N NobleONe

                      Over the last year, thanks to PC/Randy, this forum, and a lot of independent research, I've really managed to improve my research workflow. Things like:

                      • Vetting vendors more thoroughly
                      • Learning what to look for when it comes to COAs
                      • Sourcing better research supplies (carts, bac water, needles, etc.)
                      • Testing pen accuracy
                      • Reconstituting based on average peptide weight from the COA rather than the labeled amount
                      • Filtration
                      • Testing kits before researching a new batch
                      • Always low and slow (titration and patience)

                      The more I've learned, the more I've realized that most discussions revolve around efficacy, while relatively little is said about when things don't go as planned.

                      I'm not trying to start a fear-mongering thread or debate whether peptides are "safe" or "unsafe." I'm genuinely curious about the community's experiences. Your risk tolerance may vary. I personally love my peps, pep pen collection, and now 3D printer…lol

                      Has anyone experienced a reaction that went beyond a typical injection site reaction? Maybe even something that actually warranted medical evaluation or treatment? Not really looking for those who started reta at 8mg tbh, but all stories are welcomed.

                      For me personally, the worst I've experienced has been fairly mild, some bruising, occasional itching at the injection site, and a small amount of nausea after my very first Reta dose. I always start low and titrate slowly, so I haven't had any significant side effects beyond that.

                      The goal here isn't to collect horror stories. It's to better understand where the line is between a "normal reaction" and something that deserves more attention.

                      M Offline
                      M Offline
                      mary
                      wrote last edited by
                      #21

                      @NobleONe

                      Reta causes severe allodynia that I am certain will not resolve given how long its been, and that it was a milder preexisting condition. Rather than follow a schedule, it is more like; "Can the Reta be managed today, and if so, should I halve the dose?"

                      In addition to the standard recommendations, usually extra bac and splitting doses will help those who are more sensitive to peptides.

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