Priming the needle
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When you prime the needle in a pen is that expunging the air from the vial? My past experience from using Ozempic for instance each new pen you set your pen and press then you would see a drop on the tip of the needle. Is this necessary when using a V2 or V4? I pinned 1mg of Reta and I didn't notice any change in the volume of my pin. So long story short is I don't believe that I pinned any amount as it wasn't primed. Am I correct in thinking this?
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I've had pens that slip and don't push. It is a different sound. That is why buying a decent pen for a few extra bucks is worth it.
If 1 mg equated to a volume (ml, not mg) which you can easily see, then you should see the plunger move. You should easily see a 0.20 ml push. -
Most manual pens tick when you depress them. I assume you are dialing the units you want on the pen and depressing the end. You should hear clicking and see the number of units going down as you inject.
To answer your question, though, no, you shouldn’t need to prime the needle. A lot of people do see a small drop on the end of the needle when getting ready to research. I attribute this to the peptide being stored cold and some expansion/pressure due to the temp change.
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When you prime the needle in a pen is that expunging the air from the vial? My past experience from using Ozempic for instance each new pen you set your pen and press then you would see a drop on the tip of the needle. Is this necessary when using a V2 or V4? I pinned 1mg of Reta and I didn't notice any change in the volume of my pin. So long story short is I don't believe that I pinned any amount as it wasn't primed. Am I correct in thinking this?
@charlescoyle priming the needle is recommended for a couple of reasons.
To make sure your pen’s plunger is engaged with the cartridge stopper. This only really is necessary when you first mate a pen with a cartridge.
To get as much air out of the cartridge as possible.
Although injecting air subcutaneously is not as dangerous as it is with IV injections, it’s still problematic. If you hold the pen needle down, any air will be away from the needle, so it’s not too much of a problem until you get to the end of the cartridge. By priming with the needle up, you will purge as much of the air as possible over several injections.
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I use the vent needle I used to fill the cart to eliminate any extra air once I load the cart into the pen. This usually eliminates most or all of the air, and any remaining bit will usually stay in the neck of the cart as it empties (assuming you inject horizontally) so at the end, you’ll lose a couple fewer units of peptide. I rarely get air pockets these days.
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