Beyond the Scale: What Has Reta or Tirz Changed for You?
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Is it weird that I’m feeling kinda envious of people taking Reta? LOL. With the anti-inflammatory benefits and the possible cancer prevention, I’ve been thinking of microdosing it. However, I’m worried about it suppressing my appetite, which I don’t need.
Anyone microdose it without losing weight?
@jackiee I can imagine that would be a hard position to decide from. Short of engorging yourself for several months just to justify using it, I would definitely consider the method NobleOne mentioned.
I’ve seen similar approaches throughout different forums. Maybe not exactly three times a week, but people adjusting based on how their body responds, which I think is really the best approach. I’ve seen people mention going as low as 0.5 once weekly.
Obviously, I can’t tell you where the threshold for benefit would be. With it being longer-acting and building in your system over time, I would assume a lower dose could still potentially provide some of the desired benefits as it accumulates.
Trust me, I can still eat if I truly want to
I just usually end up regretting it that evening when I’m trying to sleep. -
My husband no longer needs to use his sleep apnea machine. He's breathing and not snoring. It's nice to sleep next to him.
@BeeKind That’s awesome! The snoring/breathing improvement is one of the biggest unexpected changes I’ve noticed myself. I’m sleeping better and apparently everyone around me is too
. I’d be really interested to know how much of that comes strictly from the weight loss versus other effects of these compounds. Either way, it’s pretty wild hearing how many benefits people are noticing beyond just the scale. -
@Juliano546 Great news! Congrats!
Re: joint pain, Google osteoarthritis and GLP-1’s and you can read about the anti-inflammatory benefits that result in lowered joint pain and a reduction in need for joint surgery.

It also reduces heart attack and stroke risk.
@researchcat That’s exactly what I was curious about! I was actually diagnosed with osteoarthritis at the ripe age of 22, and I’m 36 now. Over the years, and especially since using peptides and GLP-1s, I’ve started to realize that an old injury from when I was a kid likely played a big role in setting me down this path.
Between peptides/GLP-1s, massage, and chiropractic work, I’ve been able to really focus on correcting the way I walk and carry myself, and it has worked wonders for my joints. It definitely hurt at first as my body adjusted. I ran Cartalax and KLOW during that process as well, hoping to support the connective tissues that had spent most of my life being stressed in awkward positions.
Obviously that’s just my personal experience and I can’t say which piece deserves the credit, but the difference in how my joints feel today is pretty remarkable. I’m definitely going to dig deeper into the osteoarthritis/GLP-1 research. Appreciate you pointing me in that direction!

Also, congratulations on all your success with you're healing and fitness goals. For me it's an addiction, I actually appreciate for once

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I’ve lost 20 pounds so far in 4 months. 202-182. Ten more to go. My wife tells me I no longer snore. I’m 68 years old and my last blood work came back biological age of 55. Once I get to my goal of 170-173 ish pounds, I will shift to a lower maintenance dose but have no intention of stopping entirely. There are too many other benefits in addition to the weight loss to totally stop. I’ve been on a stack 5mg Tirz and 1.6mg Reta the entire time. Will shift to 2.5 Tirz and 1.0 Reta for the maintenance dose.
20 lbs in 4 months is awesome, congrats!
I’m also with you on there being benefits beyond weight loss that make me interested in what long-term maintenance might look like. I’m particularly curious to see what the research eventually tells us about Reta as more data becomes available.
And a biological age of 55 at 68?! I’d be pretty damn happy seeing that come back on my bloodwork
.Why not attempt to live longer and stronger while here for ourselves and the ones we love. Great work brother!!
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@jackiee I can imagine that would be a hard position to decide from. Short of engorging yourself for several months just to justify using it, I would definitely consider the method NobleOne mentioned.
I’ve seen similar approaches throughout different forums. Maybe not exactly three times a week, but people adjusting based on how their body responds, which I think is really the best approach. I’ve seen people mention going as low as 0.5 once weekly.
Obviously, I can’t tell you where the threshold for benefit would be. With it being longer-acting and building in your system over time, I would assume a lower dose could still potentially provide some of the desired benefits as it accumulates.
Trust me, I can still eat if I truly want to
I just usually end up regretting it that evening when I’m trying to sleep.@jackiee I can imagine that would be a hard position to decide from. Short of engorging yourself for several months just to justify using it, I would definitely consider the method NobleOne mentioned.
I’ve seen similar approaches throughout different forums. Maybe not exactly three times a week, but people adjusting based on how their body responds, which I think is really the best approach. I’ve seen people mention going as low as 0.5 once weekly.
Obviously, I can’t tell you where the threshold for benefit would be. With it being longer-acting and building in your system over time, I would assume a lower dose could still potentially provide some of the desired benefits as it accumulates.
Trust me, I can still eat if I truly want to
I just usually end up regretting it that evening when I’m trying to sleep.The .5mg per week is kind of what i was considering.
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Is it weird that I’m feeling kinda envious of people taking Reta? LOL. With the anti-inflammatory benefits and the possible cancer prevention, I’ve been thinking of microdosing it. However, I’m worried about it suppressing my appetite, which I don’t need.
Anyone microdose it without losing weight?
@jackiee You could try adding a Ghrelin agonist like Ipamorelin or MK677. I initially started Reta and Tesamorelin at the same time then swapped the Tesa for CJC/Ipa and my appetite it coming back. I still have decent control and ability to tune out food noise but I can eat if I want to.
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Tirz introduced me to Rita. Quest to possess Rita, opened the wonderful world of peptides that I was completely unaware of, and I met BPC, TB, KPV, Tesa, Survo, Cagri which all caused some dip in my bank balance but I'm sure that was covered by the lowered grocery, restaurant, and dessert bills.
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- I don't use my belt buckle to cover my unbutton pants.
- My eating habbits are more refined where every bite counts in quality over quantity.
- Considering grocery prices. You save because you eat less.
- You will start to detox
- Season allergies gone.
- Good health snowballs
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Tirz introduced me to Rita. Quest to possess Rita, opened the wonderful world of peptides that I was completely unaware of, and I met BPC, TB, KPV, Tesa, Survo, Cagri which all caused some dip in my bank balance but I'm sure that was covered by the lowered grocery, restaurant, and dessert bills.
@pep_researcher
I can relate to this one. My wife started on tirz which eventually led us to Reta that was definitely my gateway into the peptide rabbit hole too. One minute you’re researching weight loss, next thing you know you’ve got a fridge full of “research” and a browser history that needs explaining. At least we’re saving on groceries
right that is true 

-
- I don't use my belt buckle to cover my unbutton pants.
- My eating habbits are more refined where every bite counts in quality over quantity.
- Considering grocery prices. You save because you eat less.
- You will start to detox
- Season allergies gone.
- Good health snowballs
@martinmarin
#1 alone is a win. But “healthy snowballs” is probably the biggest one. one positive change starts feeding into another. Eating less, caring more about what you do eat, feeling better, moving more… it really does start to compound. -
@Mr-Smurf

“Somewhat visible” is still a hell of an upgrade! We’ll take the win. Funny how losing weight can change not only how you feel, but how the world seems to interact with you too. Im a loud person so its hard to miss me. Must be the italian in the blood hands and raised voices with a whole lot of joking, makes me hard to miss 
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@Mr-Smurf

“Somewhat visible” is still a hell of an upgrade! We’ll take the win. Funny how losing weight can change not only how you feel, but how the world seems to interact with you too. Im a loud person so its hard to miss me. Must be the italian in the blood hands and raised voices with a whole lot of joking, makes me hard to miss 
@Juliano546 oh absolutely. The world treats you way different even though its fundamentally the same person in the skin sack. Im not mad at it. Its biology to the core the fittest and finest are ones most likely to breed. This all happened so fast i havent even processed what to do with it yet lol
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@pep_researcher
I can relate to this one. My wife started on tirz which eventually led us to Reta that was definitely my gateway into the peptide rabbit hole too. One minute you’re researching weight loss, next thing you know you’ve got a fridge full of “research” and a browser history that needs explaining. At least we’re saving on groceries
right that is true 

@Juliano546 Yup, not to mention, the money saved on future lifelong prescription meds — statins, insulin, BP meds, the usual American healthcare cocktail.
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Was just telling someone the other day, I don't change, the vision I see outward is the same, however what people see is different, they look, treat you different. Its crazy concept. Reta for 3mo now, down 37lb. I think the biggest change I've experienced outside the weight loss, is the mental change of making decisions. It is way easier to pull the trigger on something I would have thought about for a lot longer. Which in itself changes life. Bank account feels the easy decisions, not only with peptides but other things too. Wonderful time to experience these things! Thanks for the info this community provides!
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Was just telling someone the other day, I don't change, the vision I see outward is the same, however what people see is different, they look, treat you different. Its crazy concept. Reta for 3mo now, down 37lb. I think the biggest change I've experienced outside the weight loss, is the mental change of making decisions. It is way easier to pull the trigger on something I would have thought about for a lot longer. Which in itself changes life. Bank account feels the easy decisions, not only with peptides but other things too. Wonderful time to experience these things! Thanks for the info this community provides!
@damic Yeah and without going in RUO details, I've been open about GLP benefits and changes to my diet to the extent of refusing dinner invites if the hosts mock my choices and force me to eat their crap.
I've noticed that some people are genuinely curious and admire, others struggling themselves but who don't want to change, parrot misinformation to cause fear and discouragement... not that I care anyway. I just laugh in my mind thinking "You have NO IDEA what you are missing!"

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watching this thread with interest since the appetite side of things is what people talk about least. the routine stuff that helped me early on was tracking protein intake and sleep alongside everything else, otherwise it's hard to tell what's actually doing what. curious whether others keep a simple log or just go by feel
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Tirzepatide helps me keep the vice noise quiet, in addition to the food noise.
I cut down from having a drink daily to MAYBE one drink every other weekend.
I stopped a vicious Elden Ring addiction

Now I can focus on work, social life, and my training with full intent.
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@atlas01 Nice work on the game. I also finally dropped a game I was spending way too much time and money on. Between the food, the booze, and the gaming, even if i spend $3k/month on peptides, I am coming out way ahead.
(Though credit where it is due, there was a lot of prayer involved as well.)
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Funny you mention gaming - I’m not really a gamer but have played a shitty phone game I started playing with my kids 10+ years ago - haven’t played it for 6 months now.
Other one is Coke - rarely touch it now - it’s been replaced by electrolytes
not because I have to - I actually prefer it now.Still punch darts
as hard as ever though.
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