What Peptide(s) Did You Expect the LEAST From but Ended Up Impressing You the Most?
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@Juliano546 thank you so much! I actually just do it SubQ…so obviously that works as well. I am slightly terrified of needles, so IM would never be on my radar!
. I just saw my doctor and told him about my glutathione injections and my progress. He was fascinated and told me to not stop and maybe we discuss increasing my dose after another month (I am only doing about 70 mg daily). He informed me there are many legitimate studies going on in relation to Glutathione/Parkinson's and Glutathione/ALS. He told me that there is so much we don’t know and that with my symptom improvement, to keep monitoring and moving forward. He fully supports it..which is also amazing!@user_6780 Might as well take my money now
I’ve been under the impression IM was the best or really the only worthwhile route for glutathione, so hearing you’ve gotten these results SubQ definitely has my attention.Also, keep that doctor for the rest of your life
. The good ones who are actually willing to listen, stay curious, and follow the research with you are hard to come by.And who would’ve thought Parkinson’s and ALS research? My wife’s grandfather battled Parkinson’s, so that especially caught my attention. The more I learn about glutathione and its role as one of the body’s major antioxidants, the more important this little three-amino-acid molecule starts looking. I clearly have some more reading to do.
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@derekg1 just got semax selank 20mg mixed by 10ml saline. Liking it pretty well started with adamax originally. I would love a adalank adamax blend
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@Mr-Smurf That’s one hell of an endorsement for Tesa
. “Weight-loss journey became a weight-loss speed run” definitely qualifies for the didn’t expect much, got way more than expected category.I’ve thought about giving Tesa a run myself. Did you experience any water retention while using it? If so, was it pretty mild or enough to actually be bothersome? That’s probably been my biggest hesitation with trying it.
@Juliano546 my experience with Tesa/Ipa has been really similar to @mr-smurf
My only negative side effect has been hunger. If I push it at night before bed it's not an issue. If I do it in the morning it overrides the Reta and fires up my appetite by midday. I take advantage of the timing, though. I'll curb my appetite with a snack, eat a decent sized meal late afternoon, fast the rest of the day, and take a second push of the Tesa/Ipa before bed. I always sleep really well those nights. I usually end up doing that every few days or so. Gotta keep my body guessing so my metabolism doesn't slow too much. -
BPC-157, TB-500.
Resisted using it considering it as hype because of the whole not approved by Eff Dee Aa thing. But a friend tried and recommended, so tried and was immensely impressed.
The most underwhelming were MOTS-C and SS-31. Waste of my money, BAC, and other supplies.
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@Juliano546 my experience with Tesa/Ipa has been really similar to @mr-smurf
My only negative side effect has been hunger. If I push it at night before bed it's not an issue. If I do it in the morning it overrides the Reta and fires up my appetite by midday. I take advantage of the timing, though. I'll curb my appetite with a snack, eat a decent sized meal late afternoon, fast the rest of the day, and take a second push of the Tesa/Ipa before bed. I always sleep really well those nights. I usually end up doing that every few days or so. Gotta keep my body guessing so my metabolism doesn't slow too much.@DarkStar Really appreciate the follow-up and especially the heads-up about the hunger. That’s exactly the kind of detail I’d want to know before giving Tesa/Ipa a run. I’d definitely lean toward a nighttime course as well, especially if morning use can start battling Reta for control of the refrigerator
.The sleep benefit is another nice bonus too. Definitely appreciate you sharing how the timing has affected your experience — gives me a lot more to consider before I eventually jump into it.
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BPC-157, TB-500.
Resisted using it considering it as hype because of the whole not approved by Eff Dee Aa thing. But a friend tried and recommended, so tried and was immensely impressed.
The most underwhelming were MOTS-C and SS-31. Waste of my money, BAC, and other supplies.
@pep_researcher I’m with you on BPC-157/TB-500. I’ve been impressed with those as well. I’m also a big fan of KLOW because of the KPV/GHK-Cu addition. Personally, it seems to settle some of the stomach issues I get from GLP-1s, and I’ve noticed a difference in my stretch marks too. I got fat faster than my skin could keep up
, so anything that helps their appearance gets my attention.MOTS-C has actually been different for me though. That one really showed itself during cardio. I noticed I could sustain harder work on the stair stepper longer than my normal baseline, which was pretty hard for me to ignore.
SS-31 is an interesting one. I wonder if part of why some people feel absolutely nothing from it is that their mitochondrial function is already in pretty good shape to begin with. Could potentially explain why it felt like an expensive donation to the BAC-water industry for you
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@DarkStar Really appreciate the follow-up and especially the heads-up about the hunger. That’s exactly the kind of detail I’d want to know before giving Tesa/Ipa a run. I’d definitely lean toward a nighttime course as well, especially if morning use can start battling Reta for control of the refrigerator
.The sleep benefit is another nice bonus too. Definitely appreciate you sharing how the timing has affected your experience — gives me a lot more to consider before I eventually jump into it.
@Juliano546 glad to be able to help!
Give it a shot. Lean into it and pack in the protein during the hunger episodes. Purely theoretical, but I feel like it's a good way to offset the days where the Reta has me struggling to get my protein and nutrients in.
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@pep_researcher I’m with you on BPC-157/TB-500. I’ve been impressed with those as well. I’m also a big fan of KLOW because of the KPV/GHK-Cu addition. Personally, it seems to settle some of the stomach issues I get from GLP-1s, and I’ve noticed a difference in my stretch marks too. I got fat faster than my skin could keep up
, so anything that helps their appearance gets my attention.MOTS-C has actually been different for me though. That one really showed itself during cardio. I noticed I could sustain harder work on the stair stepper longer than my normal baseline, which was pretty hard for me to ignore.
SS-31 is an interesting one. I wonder if part of why some people feel absolutely nothing from it is that their mitochondrial function is already in pretty good shape to begin with. Could potentially explain why it felt like an expensive donation to the BAC-water industry for you
.SS-31 is an interesting one. I wonder if part of why some people feel absolutely nothing from it is that their mitochondrial function is already in pretty good shape to begin with. Could potentially explain why it felt like an expensive donation to the BAC-water industry for you .
Yup. I've wondered that too. Tried NAD too but the precursor NR form and nothing noticeable too. So again a couple of hundred $$ down the drain. Once done with my existing MOTS-C and NR inventory, I'd be done with the whole mito research.
OTOH BPC in even pill form was impressive for my IBS.
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@Juliano546 thank you so much! I actually just do it SubQ…so obviously that works as well. I am slightly terrified of needles, so IM would never be on my radar!
. I just saw my doctor and told him about my glutathione injections and my progress. He was fascinated and told me to not stop and maybe we discuss increasing my dose after another month (I am only doing about 70 mg daily). He informed me there are many legitimate studies going on in relation to Glutathione/Parkinson's and Glutathione/ALS. He told me that there is so much we don’t know and that with my symptom improvement, to keep monitoring and moving forward. He fully supports it..which is also amazing!He was fascinated and told me to not stop...
Funny how everyone is reinventing the wheel in medicine these days. Dr. Cheney (RIP) prescribed glutathione back in the early 90s. I have read a couple of "new" studies and "new" theories in the last ten years about theories that Dr Paul Cheney was promoting at conferences for years, and had already developed protocols for.
The problem with glutathione back then is that most fringe providers that prescribed it, only gave it orally, which had a very bad absorption rate.Thanks for the subq share for NAD+! I'm going to try that.
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@user_6780 Might as well take my money now
I’ve been under the impression IM was the best or really the only worthwhile route for glutathione, so hearing you’ve gotten these results SubQ definitely has my attention.Also, keep that doctor for the rest of your life
. The good ones who are actually willing to listen, stay curious, and follow the research with you are hard to come by.And who would’ve thought Parkinson’s and ALS research? My wife’s grandfather battled Parkinson’s, so that especially caught my attention. The more I learn about glutathione and its role as one of the body’s major antioxidants, the more important this little three-amino-acid molecule starts looking. I clearly have some more reading to do.
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@Mr-Smurf Well shit, you’re definitely not helping my hesitation
. No swelling or water retention was exactly what I was curious about, and going from .75 solo up to 2.0 with .3 Ipa while still tolerating it that well is interesting.“Blast furnace level lipolysis” paired with a visceral fat score of 1–2 is one hell of an endorsement
. Tesa has been sitting on my maybe eventually list for a while, but between you and everyone else mentioning it in this thread, it’s moving up the list pretty damn quickly.And now you’ve graduated to GH
. Apparently there are levels to this. -
@juliano546 today's inbody -
Been messing with a ton of them for about 2.5yrs now. I believe most are largely placebo and people just wanting to have more out of things.
GLP1s, HGH, Tesa/Ipa, and i kiiiiiinda think MOTS-C but not really sure. Im pretty dialed in across the board.
Nothing works better than having your hormones dialed in and your T levels in that sweet spot of 850-1200 and then a good GLP1 and 2ius of GH every night.
Its the trinity. Everything else is just......whatever
@dispensarysupport I agree across the board.
Many are part of the hype train but largely placebo. I do think there is some validity to the healing compounds. BPC/TB. Hear overwhelming anecdotal evidence toward the addition of KPV. I’m personally quickly becoming a believer in MOTS.
GLPs are a miracle drug. Optimized test and IGF complete the Holy Trinity.
Can I ask, why did you go from Tesa/Ipa to HGH. Are you done with the former or do you alternate?
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I've had to take some time to put some thought into this. I've determined that I'm still too new to so many peptides out there that I couldn't give an accurate assessment except for one. Tirz. The reason it makes the exception, is that it truly has been life changing. It's helped me accomplish something health wise that I haven't been able to do in about 30 years. When I first got on it, I figured it would help the diabetes and maybe I would lose a few pounds. It's done that and much more. I would say that's a good enough standard.
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@dispensarysupport I agree across the board.
Many are part of the hype train but largely placebo. I do think there is some validity to the healing compounds. BPC/TB. Hear overwhelming anecdotal evidence toward the addition of KPV. I’m personally quickly becoming a believer in MOTS.
GLPs are a miracle drug. Optimized test and IGF complete the Holy Trinity.
Can I ask, why did you go from Tesa/Ipa to HGH. Are you done with the former or do you alternate?
Many are part of the hype train but largely placebo.
I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
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Many are part of the hype train but largely placebo.
I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
@jdot [said](/post/27549 >
Many are part of the hype train but largely placebo.I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
To add on to this, everyone's body is different. Someone may say NAD+ didn't work for them. But it just may be that their body is still producing it. The same could go for mitochondria, telemores, etc. Essentially some body's may need more help than others.
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Since the title of this thread is, "What Peptide(s) Did You Expect the LEAST From but Ended Up Impressing You the Most?", I can say that I did expect the weight loss peps to work and they do; no surprise with these peps. Was very surprised by KPV to relieve inflammation in my knee but had to take a full mg before it was noticeable. Tried Cartalax and others; all were very temporary and just didn't do it. When I upped the KPV, it was almost overnight. No placebo effect whatsoever with this one. Hoping someday a pep is found to take care of the EBV capsulates that cause the crushing fatigue I have that only let's up a bit with NAD+ & MOTS-C. Trying the Monolithin, on-going, in hopes the report is true that it breaks up the EBV caps left behind, likely to take a long time to do it though (reading 600+). I have no intention of trying a lot of new peps or supps. My gut can't handle oral supps or more peps and neither can my bank acct. I'll just have to deal with it. Ciao!
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@dispensarysupport I definitely agree there’s a placebo component with some of this stuff, especially when people start 4 things at once and somehow know exactly which one changed their life
. But I’m probably a little less skeptical overall.GLP-1s are obviously in a different league evidence-wise, but KLOW and Cartalax have given me changes noticeable enough that I personally can’t throw them into the “whatever” category. MOTS-C is newer for me, and I’m still figuring that one out, but the cardio/energy side has definitely caught my attention.
That’s actually why I like hearing from people who’ve been messing with these for a couple years though. Separating the genuinely useful stuff from the expensive placebo is half the battle
Juliano546 said:
@dispensarysupport I definitely agree there’s a placebo component with some of this stuff, especially when people start 4 things at once and somehow know exactly which one changed their life
. But I’m probably a little less skeptical overall.GLP-1s are obviously in a different league evidence-wise, but KLOW and Cartalax have given me changes noticeable enough that I personally can’t throw them into the “whatever” category. MOTS-C is newer for me, and I’m still figuring that one out, but the cardio/energy side has definitely caught my attention.
That’s actually why I like hearing from people who’ve been messing with these for a couple years though. Separating the genuinely useful stuff from the expensive placebo is half the battle
It's the GHK-cu.
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