Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • World
  • Users
  • Groups
Skins
  • Light
  • Brite
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (Zephyr)
  • No Skin
Collapse
Peptide Critic Community

Peptide Critic Community

  1. Randy the Rats Research Forum
  2. Peptide Categories
  3. Skin & Anti-Aging
  4. GHK-Cu Subcutaneous Research Dosing Protocol
March 2026 Contest
Time remaining:
6611 total entries 1000 participants
View Contest

GHK-Cu Subcutaneous Research Dosing Protocol

Scheduled Pinned Locked Moved Skin & Anti-Aging
49 Posts 8 Posters 1.3k Views 3 Watching
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • P Offline
    P Offline
    PeptidePete
    wrote on last edited by PeptidePete
    #12

    Folks understandably ask "why" the heroic dosing. To see what is on the other side is the answer 🙂 Strikes me as a reasonable experiment. Primary curiosity- assist in keeping my post-GLP3 skin tight. I am only looking to lose my ~20lbs of visceral fat but still getting some "drapy" skin nevertheless. Also, will it affect my male pattern baldness. I experienced no negative sides on daily 7.5-10mg GHK-Cu.

    Pain, yes, it can vary between nothing, and 24-36 hours not sleeping on that side pain...lol. For me the upper-outer quadrant of the buttock is where the magic is. Belly/Midriff area inevitably gets me a lump, sometimes for weeks.

    Will update thread as time passes- cheers

    C 1 Reply Last reply
    2
    • D Offline
      D Offline
      diegoc
      wrote on last edited by
      #13

      The concern was toxicity not side effects…

      Bloodwork is your best friend when your testing anything

      1 Reply Last reply
      1
      • P Offline
        P Offline
        PeptidePete
        wrote on last edited by
        #14

        Update- Continuing with 10mg GHK-Cu per day, every day. Sub-Q. Typically upper/outer quadrant of buttock and especially just above the buttock between where where the love handles used to be and the top of the cheek, about an inch or so wide.

        No negative sides. No longer have ISR (seriously I do not). My skin looks freaking awesome and feels like silk, my perpetual heel calluses are no longer cracking. As a man's man (lol) who has never done any kind of skin care, my skin to me is a reflection of overall health, ergo the high-dose GHK is justified.

        Now I wonder what 15-20mg per day would result in? Crazy talk!

        1 Reply Last reply
        1
        • P Offline
          P Offline
          PeptideEd
          wrote on last edited by
          #15

          @peptidepete Take this with the affection intended: watch your copper rbc numbers 😉 You are probably fine. But its too cheap a hedge not to take 🙂

          P D 2 Replies Last reply
          0
          • P PeptideEd

            @peptidepete Take this with the affection intended: watch your copper rbc numbers 😉 You are probably fine. But its too cheap a hedge not to take 🙂

            P Offline
            P Offline
            PeptidePete
            wrote on last edited by PeptidePete
            #16

            @PeptideEd said in GHK-Cu Subcutaneous Research Dosing Protocol:

            @peptidepete Take this with the affection intended: watch your copper rbc numbers 😉 You are probably fine. But its too cheap a hedge not to take 🙂

            Will do 👍 Labs coming up in approx 30 days. Copper is on that. Always good to stay on top of comprehensive lab work when researching aggressively!

            PS- Grok (which is very good for peptide stuff) has this to say:

            "The likelihood of experiencing copper-related problems (such as toxicity or overload) from dosing 10 mg of GHK-Cu daily appears to be low for most healthy adults without pre-existing conditions like Wilson's disease or copper metabolism disorders. Here's a breakdown of the reasoning: Copper Content in GHK-Cu (glycyl-L-histidyl-L-lysine copper) contains approximately 15-19% elemental copper by weight, depending on the exact formulation.

            At 10 mg of GHK-Cu, this equates to roughly 1.5-1.9 mg of elemental copper per dose.

            The Recommended Dietary Allowance (RDA) for copper in adults is about 0.9-1.3 mg per day, primarily from diet. Average daily dietary intake is 1-1.6 mg.
            The Tolerable Upper Intake Level (UL) for elemental copper from all sources (diet + supplements) is 10 mg per day for adults, per health authorities like the NIH. Exceeding this chronically can increase risks, but 10 mg GHK-Cu adds only ~1.5-1.9 mg, bringing total daily copper (including diet) to around 2.5-3.5 mg—well below the UL."

            Looking good for that boost to 20mg! 🤣

            1 Reply Last reply
            0
            • RandyR Offline
              RandyR Offline
              Randy
              wrote on last edited by
              #17

              Just a little update on me. Im doing 3mgs a day now. Might go to 5 for the culture. If one of you goes to 20 ill have no choice but to go to 21.

              "If it doesnt come in a needle. It doesn't work"

              P 1 Reply Last reply
              3
              • P Offline
                P Offline
                PeptideEd
                wrote on last edited by
                #18

                Blackjack

                1 Reply Last reply
                1
                • D Offline
                  D Offline
                  diegoc
                  wrote on last edited by
                  #19

                  Well i upd my dose.
                  2.5mg SubQ daily
                  2mg Buccal strip
                  About 500mcg 2x daily face cream.

                  Does anyone know the Quest or Labcorp code fot copper?

                  If my numbers are low i will bump up more

                  1 Reply Last reply
                  0
                  • P PeptideEd

                    @peptidepete Take this with the affection intended: watch your copper rbc numbers 😉 You are probably fine. But its too cheap a hedge not to take 🙂

                    D Offline
                    D Offline
                    diegoc
                    wrote on last edited by
                    #20

                    @PeptideEd hey bud, are you going to give us some of your copper tricks of the trade?

                    1 Reply Last reply
                    0
                    • P Offline
                      P Offline
                      PeptideEd
                      wrote on last edited by
                      #21

                      @diegoc LOL - I don't feel like I'm that sophisticated a GHKCU user... but the meager tricks I do have I'm happy to share.

                      I get my blood work done via Ultalabs which uses Quest under the covers. The two tests I do roughly monthly for copper are:

                      1. Copper RBC - which is a decent proxy for cellular copper status - I use this to watch out for copper toxicity.
                      2. Zinc RBC - which I use to check zinc cellular levels.

                      Having the Zinc/Copper ratio to far out of balance leads to all kinds of downstream mischief... independent of actual copper toxicity. In my case my zinc rbc pointed to the need to supplement zinc more than I had been doing.

                      My only other trick really is to dilute with more bac water to reduce stinging as @randy recommended in this video.

                      Hope some of that helps 🙂

                      D 1 Reply Last reply
                      0
                      • RandyR Randy

                        Just a little update on me. Im doing 3mgs a day now. Might go to 5 for the culture. If one of you goes to 20 ill have no choice but to go to 21.

                        P Offline
                        P Offline
                        PeptidePete
                        wrote on last edited by
                        #22

                        @Randy said in GHK-Cu Subcutaneous Research Dosing Protocol:

                        Just a little update on me. Im doing 3mgs a day now. Might go to 5 for the culture. If one of you goes to 20 ill have no choice but to go to 21.

                        😂 LOL!

                        I remain on 10mg daily and my wife got pissed at my skin and demanded to start pinning it even though she does not care for multiple shots per day. She tolerated 2.5mg with no ISR and I bumped her to 5mg where she is now.

                        I am finishing off 63mg vials with 3ml BAC, then I dilute again in the inj syringe prior to pinning.

                        I really like Dr Kristi Sawicki on YT, smart independent thinking person: Link

                        Her perspective on GHK and cancer, with her background, is quite thought provoking. Quite...

                        D 1 Reply Last reply
                        0
                        • P PeptidePete

                          @Randy said in GHK-Cu Subcutaneous Research Dosing Protocol:

                          Just a little update on me. Im doing 3mgs a day now. Might go to 5 for the culture. If one of you goes to 20 ill have no choice but to go to 21.

                          😂 LOL!

                          I remain on 10mg daily and my wife got pissed at my skin and demanded to start pinning it even though she does not care for multiple shots per day. She tolerated 2.5mg with no ISR and I bumped her to 5mg where she is now.

                          I am finishing off 63mg vials with 3ml BAC, then I dilute again in the inj syringe prior to pinning.

                          I really like Dr Kristi Sawicki on YT, smart independent thinking person: Link

                          Her perspective on GHK and cancer, with her background, is quite thought provoking. Quite...

                          D Offline
                          D Offline
                          diegoc
                          wrote on last edited by
                          #23

                          @PeptidePete hey “Copper Pete” lol

                          I just whipped up a batch of KLOW Since i was doing all the other peptides for my Gut I figured i would RS the max dose on copper.

                          Its crazy because i dont know if my body/butt will tolerate those mgs.

                          I went from 2mg to 2.5 in KLOW and i feel it, so lets see if i can keep uping the dose however I will add the copper toxicity test this month.

                          I do see all my fine wrinkles disappear, what are you seeing on your end thats mind blowing?

                          D 1 Reply Last reply
                          0
                          • P PeptideEd

                            @diegoc LOL - I don't feel like I'm that sophisticated a GHKCU user... but the meager tricks I do have I'm happy to share.

                            I get my blood work done via Ultalabs which uses Quest under the covers. The two tests I do roughly monthly for copper are:

                            1. Copper RBC - which is a decent proxy for cellular copper status - I use this to watch out for copper toxicity.
                            2. Zinc RBC - which I use to check zinc cellular levels.

                            Having the Zinc/Copper ratio to far out of balance leads to all kinds of downstream mischief... independent of actual copper toxicity. In my case my zinc rbc pointed to the need to supplement zinc more than I had been doing.

                            My only other trick really is to dilute with more bac water to reduce stinging as @randy recommended in this video.

                            Hope some of that helps 🙂

                            D Offline
                            D Offline
                            diegoc
                            wrote on last edited by
                            #24

                            @PeptideEd Mr Ed i really appreciate your tricks. Lol

                            I will order the exact test.

                            Whats a good ratio that is good for Research from Copper to Zinc.

                            Thanks

                            1 Reply Last reply
                            0
                            • D diegoc

                              @PeptidePete hey “Copper Pete” lol

                              I just whipped up a batch of KLOW Since i was doing all the other peptides for my Gut I figured i would RS the max dose on copper.

                              Its crazy because i dont know if my body/butt will tolerate those mgs.

                              I went from 2mg to 2.5 in KLOW and i feel it, so lets see if i can keep uping the dose however I will add the copper toxicity test this month.

                              I do see all my fine wrinkles disappear, what are you seeing on your end thats mind blowing?

                              D Offline
                              D Offline
                              diegoc
                              wrote on last edited by
                              #25

                              Now im pissed….

                              Just pinned 2mg of GHK on each but cheeck….

                              So if i put a target on my but im sure i can do 10mgs a day. Lol

                              P 1 Reply Last reply
                              0
                              • D diegoc

                                Now im pissed….

                                Just pinned 2mg of GHK on each but cheeck….

                                So if i put a target on my but im sure i can do 10mgs a day. Lol

                                P Offline
                                P Offline
                                PeptidePete
                                wrote on last edited by PeptidePete
                                #26

                                @diegoc said in GHK-Cu Subcutaneous Research Dosing Protocol:

                                Now im pissed….

                                Just pinned 2mg of GHK on each but cheeck….

                                So if i put a target on my but im sure i can do 10mgs a day. Lol

                                LOL! It acts on 3000 genes! Go for the gusto!

                                😀

                                PS- my best spot is the soft area (previously a love handle) between upper check and lower back, never any pain. 10mg+ goes in one spot like buttah!!

                                D 1 Reply Last reply
                                0
                                • P PeptidePete

                                  @diegoc said in GHK-Cu Subcutaneous Research Dosing Protocol:

                                  Now im pissed….

                                  Just pinned 2mg of GHK on each but cheeck….

                                  So if i put a target on my but im sure i can do 10mgs a day. Lol

                                  LOL! It acts on 3000 genes! Go for the gusto!

                                  😀

                                  PS- my best spot is the soft area (previously a love handle) between upper check and lower back, never any pain. 10mg+ goes in one spot like buttah!!

                                  D Offline
                                  D Offline
                                  diegoc
                                  wrote on last edited by
                                  #27

                                  @PeptidePete picture of the spot please 🙏🏼🤣

                                  P 1 Reply Last reply
                                  0
                                  • D Offline
                                    D Offline
                                    diegoc
                                    wrote on last edited by
                                    #28

                                    @peptidepete ok Pete…

                                    3mg of KLOW on each new LoveHandle/upperButtocks

                                    Like Butter.!!!

                                    So im up to 6mg GHK Subq, 2mg Sublingual, 1mg Topical…

                                    I think i will test 7mg max Subq and test for copper end of Feb as per @peptideed recommendations.

                                    Zinc came in middle to upper range so not low

                                    1 Reply Last reply
                                    0
                                    • D diegoc

                                      @PeptidePete picture of the spot please 🙏🏼🤣

                                      P Offline
                                      P Offline
                                      PeptidePete
                                      wrote on last edited by
                                      #29

                                      @diegoc said in GHK-Cu Subcutaneous Research Dosing Protocol:

                                      @PeptidePete picture of the spot please 🙏🏼🤣

                                      I actually do have limits 😨 😂

                                      Currently researching 12mg per pin, probing for sides. So far none. My suspicion, based on zero facts and an N of one, is GHK is going to turn out to be a key ingredient to healthspan optimization and perhaps longevity as well.

                                      D RandyR 2 Replies Last reply
                                      0
                                      • P PeptidePete

                                        @diegoc said in GHK-Cu Subcutaneous Research Dosing Protocol:

                                        @PeptidePete picture of the spot please 🙏🏼🤣

                                        I actually do have limits 😨 😂

                                        Currently researching 12mg per pin, probing for sides. So far none. My suspicion, based on zero facts and an N of one, is GHK is going to turn out to be a key ingredient to healthspan optimization and perhaps longevity as well.

                                        D Offline
                                        D Offline
                                        diegoc
                                        wrote on last edited by
                                        #30

                                        @PeptidePete thats pretty insane how high you can tolerate.

                                        My 3mg each side my hips are like Shakira Hips…

                                        Mild spicy, not Hot but good feeling spicy.

                                        I will do a week and up the dose.💪

                                        1 Reply Last reply
                                        1
                                        • P PeptidePete

                                          @diegoc said in GHK-Cu Subcutaneous Research Dosing Protocol:

                                          @PeptidePete picture of the spot please 🙏🏼🤣

                                          I actually do have limits 😨 😂

                                          Currently researching 12mg per pin, probing for sides. So far none. My suspicion, based on zero facts and an N of one, is GHK is going to turn out to be a key ingredient to healthspan optimization and perhaps longevity as well.

                                          RandyR Offline
                                          RandyR Offline
                                          Randy
                                          wrote on last edited by
                                          #31

                                          @PeptidePete 12!?!?!?!? ok im going to 15.

                                          "If it doesnt come in a needle. It doesn't work"

                                          1 Reply Last reply
                                          1
                                          Reply
                                          • Reply as topic
                                          Log in to reply
                                          • Oldest to Newest
                                          • Newest to Oldest
                                          • Most Votes


                                          • Login

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Categories
                                          • Recent
                                          • Tags
                                          • Popular
                                          • World
                                          • Users
                                          • Groups