Nexaph reliability?
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@pep_researcher The main purity/mass testing for the some Tesamorelin I just received is showing Freedom Labs - please note - I don't think this is a concern to me... but it appears to be more than just the group tests.
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@pep_researcher The main purity/mass testing for the some Tesamorelin I just received is showing Freedom Labs - please note - I don't think this is a concern to me... but it appears to be more than just the group tests.
@PeptideEd There's also the Janoshik mass/purity results tab right next to it showing different numbers. The concern is about difference. The TG channel mods said something about how each lab calculates expients, but then wouldn't that be same for all other compounds too, and wouldn't that be same for different batches within the same compound?
Was there a change in manufacturing process and raws?
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@pep_researcher The main purity/mass testing for the some Tesamorelin I just received is showing Freedom Labs - please note - I don't think this is a concern to me... but it appears to be more than just the group tests.
@PeptideEd From Cain
Hi Steven,
We are not changing and will continue to use Janoshik as they are the gold standard.
They have the Janoshik COA there as well. Tested at two labs, and they show both; you just can't beat them. Freedom clearly has issues. Janoshik shows 3 vials tested for Mass, ID and Purity all very close. Plus Endotxins, Heavy metals and soon sterility all Janoshik.
If you want to buy from the gold standard, you found it. As Jeff calls it the easy button, you may pay more but its piece of mind
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@stevepep sorry to have gotten that wrong... I'd missed the second mass/purity tab
Now I just have to figure out how to get all the direct QR codes onto my labels and still remain phone scannable on a curved vial surface @pep_researcher I see that now... I am over all super pleased with the test coverage... but a little concerned about the less than 99% purity test from Jashonik.
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@stevepep sorry to have gotten that wrong... I'd missed the second mass/purity tab
Now I just have to figure out how to get all the direct QR codes onto my labels and still remain phone scannable on a curved vial surface @pep_researcher I see that now... I am over all super pleased with the test coverage... but a little concerned about the less than 99% purity test from Jashonik.
@PeptideEd Ya, I wouldn't have ordered it, to be honest. The cat's out of the bag, though, so filter it and go slow.
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@stevepep sorry to have gotten that wrong... I'd missed the second mass/purity tab
Now I just have to figure out how to get all the direct QR codes onto my labels and still remain phone scannable on a curved vial surface @pep_researcher I see that now... I am over all super pleased with the test coverage... but a little concerned about the less than 99% purity test from Jashonik.
concerned about the less than 99% purity test
Yup that was my point too.
Nevertheless I wanted to say that I still appreciate their brutal honesty. They could've just displayed Freedom COA saying they used Freedom for this batch.
So despite this anomaly, between them and a vendor hopping multiple labs for every batch, I would pick Nexa.
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I wish Nexaph had lower prices… They were not too bad before that price jump, still not as cheap as the other grey market suppliers but reasonable enough where it was a good place for people to go buy 1 or 2 kits at a time from. But $468 for a kit of KLOW, who could really afford that, not me I don’t have that kind of cash...
Please excuse my typos. Small Phone & Bad Eyes
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@stevepep sorry to have gotten that wrong... I'd missed the second mass/purity tab
Now I just have to figure out how to get all the direct QR codes onto my labels and still remain phone scannable on a curved vial surface @pep_researcher I see that now... I am over all super pleased with the test coverage... but a little concerned about the less than 99% purity test from Jashonik.
@PeptideEd If you create tiny url's for the QR code, they can be printed smaller and still be scannable.
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I wish Nexaph had lower prices… They were not too bad before that price jump, still not as cheap as the other grey market suppliers but reasonable enough where it was a good place for people to go buy 1 or 2 kits at a time from. But $468 for a kit of KLOW, who could really afford that, not me I don’t have that kind of cash...
s the other grey market suppliers but reasonable enough where it was a good place for people to go buy 1 or 2 kits at a time from. But $468 for a kit of KLOW, who could really afford that, not me I don’t have that kind of cash...
yeah the klow price hike is insane. Used to be 178
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s the other grey market suppliers but reasonable enough where it was a good place for people to go buy 1 or 2 kits at a time from. But $468 for a kit of KLOW, who could really afford that, not me I don’t have that kind of cash...
yeah the klow price hike is insane. Used to be 178
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@PeptideEd I just clicked on the box with the arrow, and it takes you directly to the COA on Janoshiks website
@Stevepep This new 97% tested batch of Tesa is now on EZ and AMP too. I appreciate the honesty too, but the previous batches were tested over 99% at Janoshik. I kind of get used already to see 99+% for the products I buy. There is 99.9% COA from Freedom for the same batch though, but we know there are issues with them. In Nexaph TG group they stated that they looked for "97% purity or more" from the test, so they got what they expected, but there are other products at higher level, and their own previous batches were at 99.7% levels.
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@Stevepep This new 97% tested batch of Tesa is now on EZ and AMP too. I appreciate the honesty too, but the previous batches were tested over 99% at Janoshik. I kind of get used already to see 99+% for the products I buy. There is 99.9% COA from Freedom for the same batch though, but we know there are issues with them. In Nexaph TG group they stated that they looked for "97% purity or more" from the test, so they got what they expected, but there are other products at higher level, and their own previous batches were at 99.7% levels.
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s the other grey market suppliers but reasonable enough where it was a good place for people to go buy 1 or 2 kits at a time from. But $468 for a kit of KLOW, who could really afford that, not me I don’t have that kind of cash...
yeah the klow price hike is insane. Used to be 178
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@vpeptides So what are the true downsides to 97% instead of 99%? Just a weaker product (less bang for your buck), failure in the lypholization process, or something else?
@Nuncles That means these 2% of the AUC on HPLC chart belong not to Tesamorelin but to something else, maybe a broken chain or a different peptide. Who knows, they don't show us peasants the charts. But you can't also tell what is it from HPLC chart, you may guess something from LC-MS charts (or whatever they use for identity), but they don't show it either.
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@vpeptides So what are the true downsides to 97% instead of 99%? Just a weaker product (less bang for your buck), failure in the lypholization process, or something else?
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@steve @vpeptides Thanks for the education. Where, or which process, does this "other 2%" most likely come from? Any educated guesses of the most likely place/cause? I don't have a complete understanding of how peptides are created and the process it takes to get to us, but I'm trying to somewhat fill in the blanks.
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@steve @vpeptides Thanks for the education. Where, or which process, does this "other 2%" most likely come from? Any educated guesses of the most likely place/cause? I don't have a complete understanding of how peptides are created and the process it takes to get to us, but I'm trying to somewhat fill in the blanks.
@Nuncles if it’s Nexaph it’s likely degradation. Could be moisture or salt. That’s a guess because it could be anything like a breakdown in the chain, another peptide etc. I am familiar with the nutraceutical space so I know the process. We don’t get enough info on the COA to really make that determination because they don’t show the compounds individually
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@Nuncles if it’s Nexaph it’s likely degradation. Could be moisture or salt. That’s a guess because it could be anything like a breakdown in the chain, another peptide etc. I am familiar with the nutraceutical space so I know the process. We don’t get enough info on the COA to really make that determination because they don’t show the compounds individually
@Stevepep actually Freedom COA shows MS chart, here what it is, and it is not a full intact Tesa molecule, it's a contaminant. Freedom also identifies Histidine spike but it is ignored, and its m/z doesn't match these levels.
AI guesses it can be Phenylalanine or another source-induced breakdown product of Tesamorelin. It could even be created by the measurement operation itself.
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