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Peptide Critic Community

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  1. Randy the Rats Research Forum
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  3. Healing & Recovery
  4. SS-31 (Elamipretide) — Research Dosing Protocol
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SS-31 (Elamipretide) — Research Dosing Protocol

Scheduled Pinned Locked Moved Healing & Recovery
53 Posts 15 Posters 1.2k Views 4 Watching
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  • R ResearchCat

    That is really timely. I was just starting to look at FOX-04 DRI, and just saw a new video on it. It seems like with all the attention SS-31/MOTS-C/NAD+ are getting that FOX is as well. Clearing out senescent cells sounds like a great idea, but I’d be a bit concerned with killing off 10%(one number I saw) of my cells without better understanding of what they get replaced with.

    Definitely requires a bit more research on my part. Thank goodness it’s expensive. 🙂

    B Offline
    B Offline
    beachfun
    wrote on last edited by
    #39

    @ResearchCat Im a bit conservative about jumping in to that Fox clean out…Doing a 7 day fast should do the clearing out of damaged cells naturally. I started with MotsC now going to run Just SS 31 with 5 amino 1Q for a month. I had been exposed to mold at times and leaning more on healing and recovery before anything too aggressive. Diego has some knowledge but is aggressive. Im 62 and still working hard so I will try this for restoration. I did love the MotC for the week but felt it was needing more each day so fixing the leaking mitochondria seems to be my plan.

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    • dneunerD Offline
      dneunerD Offline
      dneuner
      wrote last edited by
      #40

      I just started the SS-31 protocol Randy shared above. Question for the community....what is a good follow up protocol moving onto MOT-C when I finish the SS-31 protocol? When I repair the good remaining cells, what's a good cycle for fueling them? Thank you for your input!

      M 1 Reply Last reply
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      • dneunerD dneuner

        I just started the SS-31 protocol Randy shared above. Question for the community....what is a good follow up protocol moving onto MOT-C when I finish the SS-31 protocol? When I repair the good remaining cells, what's a good cycle for fueling them? Thank you for your input!

        M Offline
        M Offline
        MacLeeezy
        wrote last edited by
        #41
        This post is deleted!
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        • M Offline
          M Offline
          MacLeeezy
          wrote last edited by MacLeeezy
          #42

          Hey good Afternoon. I have a 10pack of 50mg SS31 on the way to research with. This is about 14 vials short of being able to complete this protocol.

          I am looking to do a miniature version of this and would appreciate any feedback from the community on if you think this will work well given my limited supplies or if I’m titrating up too quickly:

          Weeks 1-3: 4mg Daily
          Weeks 4-6: 8mg Daily
          Weeks 7-9: 25mg 3 times per week

          Thanks!

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          • M MacLeeezy

            Hey good Afternoon. I have a 10pack of 50mg SS31 on the way to research with. This is about 14 vials short of being able to complete this protocol.

            I am looking to do a miniature version of this and would appreciate any feedback from the community on if you think this will work well given my limited supplies or if I’m titrating up too quickly:

            Weeks 1-3: 4mg Daily
            Weeks 4-6: 8mg Daily
            Weeks 7-9: 25mg 3 times per week

            Thanks!

            D Offline
            D Offline
            diegoc
            wrote last edited by
            #43

            @MacLeeezy im doing this protocol and i bought the 1gr required.

            If you dont have enough probably cut on the 25mg and lower that dosez

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            • I Offline
              I Offline
              iMemphis
              wrote last edited by iMemphis
              #44

              My rat just got ss-31 in today and after reading this, I think

              Weeks 1-3: 4mg Daily
              Weeks 4-6: 8mg Daily

              should work yes?

              @macleeezy @diegoc since you guys are both using this for your rats also, did you guys notice anything when doign 4mg right off the bat?

              just to confirm:

              Using the peptide calculator,

              Desired dose is 4MG,
              Vial size is 10MG
              2ML bac water

              I would need to give my Rat 80 units daily?

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              • P Offline
                P Offline
                PeptideEd
                wrote last edited by
                #45

                @imemphis I've done 4mg (just finished that part and moved to 10mg in the last few days) - was a pretty easy adjustment. That said, and with the caveat that the following comment is a matter of taste, I'd go with 1 mL to a 10mg vial and do 40 units. From where I sit, for me, 80 units is a lot in an injection. When I did 4mg I did specifically 10mg/mL concentration and thus 40 units for 4mg. To be clear, its a matter of taste, there's nothing wrong with your plan if 80 unit shots are comfortable for you 🙂

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                • I Offline
                  I Offline
                  iMemphis
                  wrote last edited by
                  #46

                  Thanks for the heads up @peptideed !

                  1 Reply Last reply
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                  • P Offline
                    P Offline
                    PeptideEd
                    wrote last edited by
                    #47

                    @imemphis oh... and when I transitioned to 10mg a day recently, I switched to a 20mg/mL concentration (50 units to get 10mg). Injection went smoothly.

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                    • I iMemphis

                      My rat just got ss-31 in today and after reading this, I think

                      Weeks 1-3: 4mg Daily
                      Weeks 4-6: 8mg Daily

                      should work yes?

                      @macleeezy @diegoc since you guys are both using this for your rats also, did you guys notice anything when doign 4mg right off the bat?

                      just to confirm:

                      Using the peptide calculator,

                      Desired dose is 4MG,
                      Vial size is 10MG
                      2ML bac water

                      I would need to give my Rat 80 units daily?

                      M Offline
                      M Offline
                      MacLeeezy
                      wrote last edited by
                      #48

                      @iMemphis I’m just planning for the future. I have a kit of SS-31 but haven’t started it yet. Planning on running fox04-dri first but need to finish up a couple other thing first

                      1 Reply Last reply
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                      • R Offline
                        R Offline
                        ResearchCat
                        wrote last edited by
                        #49

                        I just finished my SS-31 run. I decided to do phases 1-2 and skip the burst phase mainly due to costs. I did a concentration of 10mg in 40 units (~24mg/ml). I occasional mild ISR but no worse than from 12 units of glow. I found using the gansulin pen made it a breeze.

                        Now running MOTS-C and planning to add NAD+.

                        1 Reply Last reply
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                        • MyBM Offline
                          MyBM Offline
                          MyB
                          wrote last edited by
                          #50

                          @researchcat Dr Sawicki dropped a short on YouTube about how antioxidants block Mot-C from entering the cell. So you’ll probably want to research Mot and NAD on different runs.
                          https://youtube.com/shorts/W2a9qZ7vP1k?si=3-iRJFN2so7hVyLx

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                          • MyBM MyB

                            @researchcat Dr Sawicki dropped a short on YouTube about how antioxidants block Mot-C from entering the cell. So you’ll probably want to research Mot and NAD on different runs.
                            https://youtube.com/shorts/W2a9qZ7vP1k?si=3-iRJFN2so7hVyLx

                            R Offline
                            R Offline
                            ResearchCat
                            wrote last edited by ResearchCat
                            #51

                            @MyB that’s interesting. My inclination was to do them all separately, but it seems a lot of people (YouTubers) are suggesting you blast everything all together. Appreciate the tip.

                            Edit: Oh, I see, so not saying you can’t research them together, but that you shouldn’t research them at the same time of day.

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                            • MyBM Offline
                              MyBM Offline
                              MyB
                              wrote last edited by
                              #52

                              @researchcat i made a post under the mot-c dosing topic. https://community.peptidecritic.com/post/2819
                              Based on half life’s, dosing Mot-C then dose NAD+ 8 hrs later would get full benefits of both without overlap.

                              1 Reply Last reply
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                              • MyBM MyB

                                @researchcat Dr Sawicki dropped a short on YouTube about how antioxidants block Mot-C from entering the cell. So you’ll probably want to research Mot and NAD on different runs.
                                https://youtube.com/shorts/W2a9qZ7vP1k?si=3-iRJFN2so7hVyLx

                                M Offline
                                M Offline
                                MacLeeezy
                                wrote last edited by
                                #53
                                This post is deleted!
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