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Klotho / FLGR242 (albumin-bound new tech)

Scheduled Pinned Locked Moved Peptide Discussion
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586 Posts 41 Posters 62.9k Views 9 Watching
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  • P Offline
    P Offline
    PeptidePete
    wrote last edited by PeptidePete
    #564

    Update:

    New labs look great Cystatin C 1.11->1.04, Iron/TBIC/Ferritin finally all within optimum range. Stamina ever increasing (fixed ferritin).

    Completed SS-31 2 month 50mg daily run, surprising effect on urine flow increase. Wonder if synergistic in combo with the Klotho? Could be/Should be when you think it. The cost of SS-31, first off I loaded up from multiple vendors who were blowing out stocks Dec-Feb in fear, second, QSC offers 50mg at .70/mg. Understand screaming deals when you see them, then, act on them. In regards to expense, what I look at is value, what else is proven to do what elamipretide does? Nothing. I plan to run another two month course in a couple months from now, so 2 on, then 3 off, rinse repeat.

    BTW- the proven minimum efficacious dose is what it is, I've seen zero evidence anything less than 40mg daily is effective, indeed the opposite. The molecule doesn't care if anyone likes that or not.

    Ran an experiment stopping variable-resistance training for two months to observe effect on Skeletal Muscle Mass, shock, only dropped 1lb. There is another benefit I attribute to FLGR. Maintain the gain if you go on vacation for a couple months 🙂

    vpepsV 1 Reply Last reply
    3
    • P PeptidePete

      Update:

      New labs look great Cystatin C 1.11->1.04, Iron/TBIC/Ferritin finally all within optimum range. Stamina ever increasing (fixed ferritin).

      Completed SS-31 2 month 50mg daily run, surprising effect on urine flow increase. Wonder if synergistic in combo with the Klotho? Could be/Should be when you think it. The cost of SS-31, first off I loaded up from multiple vendors who were blowing out stocks Dec-Feb in fear, second, QSC offers 50mg at .70/mg. Understand screaming deals when you see them, then, act on them. In regards to expense, what I look at is value, what else is proven to do what elamipretide does? Nothing. I plan to run another two month course in a couple months from now, so 2 on, then 3 off, rinse repeat.

      BTW- the proven minimum efficacious dose is what it is, I've seen zero evidence anything less than 40mg daily is effective, indeed the opposite. The molecule doesn't care if anyone likes that or not.

      Ran an experiment stopping variable-resistance training for two months to observe effect on Skeletal Muscle Mass, shock, only dropped 1lb. There is another benefit I attribute to FLGR. Maintain the gain if you go on vacation for a couple months 🙂

      vpepsV Offline
      vpepsV Offline
      vpeps
      wrote last edited by
      #565

      @PeptidePete said:

      Iron/TBIC/Ferritin finally all within optimum range

      What do you consider as optimal values for these?

      attentiion is all you need

      P 1 Reply Last reply
      0
      • MacLeeezyM Offline
        MacLeeezyM Offline
        MacLeeezy
        wrote last edited by
        #566

        Just got an email from biolongevity that said once they sell out of their remaining 700 vials, “slim assist” will be NO more…

        D quicksilver80Q 2 Replies Last reply
        1
        • ResearchCatR Online
          ResearchCatR Online
          ResearchCat
          wrote last edited by
          #567

          Yeah, but they said that in the last sale, too.

          Yeah, well, I’m just here for the research, man. - The Dude

          If I haven’t liked your post, no offense. I have exceeded my daily allowance.

          1 Reply Last reply
          2
          • vpepsV vpeps

            @PeptidePete said:

            Iron/TBIC/Ferritin finally all within optimum range

            What do you consider as optimal values for these?

            P Offline
            P Offline
            PeptidePete
            wrote last edited by
            #568

            @vpeps said:

            @PeptidePete said:

            Iron/TBIC/Ferritin finally all within optimum range

            What do you consider as optimal values for these?

            It's a great question! I do agree with @diegoc too much is probably not good.

            HOWEVER, too low is most certainly a BIG problem, "therapeutic" phlebotomy caused me years of lack of stamina and suboptimal energy, and FLGR this year further drained my ferritin reserves as it let my muscle (re)growth run unchecked (a good thing).

            So now I'm on to the hematocrit OMG IT WILL KILL YOU!! scam and gloriously let it run free as well. Pull the string if you want to really get pissed off.

            Tangent mini-rant- if you are dealing with secondary erythrocytosis driven by exogenous testosterone, hematocrit is MEANINGLESS. Just like Estradiol level is MEANINGLESS. (pull the string) IGNORE. It's GOOD not bad.

            Back to the question, on this I am quite comfortable to be in the Labcorp reference intervals. See attached.

            The more you dig the more you discover so many so-called experts have no fucking clue what they are talking about. Recommendations based solely upon "Expert opinion" is utter BS. Be your own advocate and trust NO ONE unless claims are thoroughly vetted.

            2.jpg 1.jpg

            1 Reply Last reply
            1
            • vpepsV Offline
              vpepsV Offline
              vpeps
              wrote last edited by
              #569

              @PeptidePete Ferritin 30 - 400 ng/ml is quite a range to call both extremes normal. Your values around 90 look a lot healthier than 31 or 390 would.

              attentiion is all you need

              1 Reply Last reply
              0
              • MacLeeezyM MacLeeezy

                Just got an email from biolongevity that said once they sell out of their remaining 700 vials, “slim assist” will be NO more…

                D Offline
                D Offline
                denti
                wrote last edited by
                #570

                @MacLeeezy said:

                Just got an email from biolongevity that said once they sell out of their remaining 700 vials, “slim assist” will be NO more…

                If they want to sell out quicker let them know to run another 50% off and I will buy 200 of their vials 🙂

                1 Reply Last reply
                1
                • vpepsV vpeps

                  @denti Slim Assist is still available.

                  D Offline
                  D Offline
                  denti
                  wrote last edited by
                  #571

                  @vpeps said:

                  @denti Slim Assist is still available.

                  Looks like the buy 10 get 15 free is now gone 😕

                  Been checking every few days for a lower price to stock up more, but now getting a good deal again seems to be dead.

                  vpepsV 1 Reply Last reply
                  0
                  • MacLeeezyM MacLeeezy

                    Just got an email from biolongevity that said once they sell out of their remaining 700 vials, “slim assist” will be NO more…

                    quicksilver80Q Offline
                    quicksilver80Q Offline
                    quicksilver80
                    wrote last edited by
                    #572

                    @MacLeeezy they gave everyone a taste and switched them to the genuine article once hooked at full price lol

                    1 Reply Last reply
                    2
                    • D denti

                      @vpeps said:

                      @denti Slim Assist is still available.

                      Looks like the buy 10 get 15 free is now gone 😕

                      Been checking every few days for a lower price to stock up more, but now getting a good deal again seems to be dead.

                      vpepsV Offline
                      vpepsV Offline
                      vpeps
                      wrote last edited by
                      #573

                      @denti I wouldn't worry about it if you need to run it but have some. Use what you have and wait for, you know, 50% sales on FLRG242. It's the holiday season coming.

                      attentiion is all you need

                      D 1 Reply Last reply
                      1
                      • vpepsV vpeps

                        @denti I wouldn't worry about it if you need to run it but have some. Use what you have and wait for, you know, 50% sales on FLRG242. It's the holiday season coming.

                        D Offline
                        D Offline
                        denti
                        wrote last edited by
                        #574

                        @vpeps said:

                        @denti I wouldn't worry about it if you need to run it but have some. Use what you have and wait for, you know, 50% sales on FLRG242. It's the holiday season coming.

                        I got 40 vials left but looking to step up to 2x a week now. Still gives me 5 months but I still like having a stock. Hopefully deal comes back again.

                        1 Reply Last reply
                        0
                        • Mr SmurfM Offline
                          Mr SmurfM Offline
                          Mr Smurf
                          wrote last edited by
                          #575

                          I've got like 26 2mg vials left. Honestly if this is it, im good with it. I've personally found them to be a ridiculously OP ancillary to some stronger stuff that I run, basically allowing me to dose that stuff lower and get an oversized effect out of it. Hopefully not a controversial take just what ive found has worked exceptionally well for me.

                          ResearchCatR D 2 Replies Last reply
                          0
                          • Mr SmurfM Mr Smurf

                            I've got like 26 2mg vials left. Honestly if this is it, im good with it. I've personally found them to be a ridiculously OP ancillary to some stronger stuff that I run, basically allowing me to dose that stuff lower and get an oversized effect out of it. Hopefully not a controversial take just what ive found has worked exceptionally well for me.

                            ResearchCatR Online
                            ResearchCatR Online
                            ResearchCat
                            wrote last edited by
                            #576

                            @Mr-Smurf Well, I hit my upvote limit early today. 😉

                            IMO, it’s always good to hear people’s real world experiences. I haven’t started using my stock of FLGR yet, but I am happy to see what others are doing and how it is working for them. I need to gain muscle mass. I’m starting to look like Ed Norton. (Without all the tats.)

                            Yeah, well, I’m just here for the research, man. - The Dude

                            If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                            1 Reply Last reply
                            0
                            • Mr SmurfM Mr Smurf

                              I've got like 26 2mg vials left. Honestly if this is it, im good with it. I've personally found them to be a ridiculously OP ancillary to some stronger stuff that I run, basically allowing me to dose that stuff lower and get an oversized effect out of it. Hopefully not a controversial take just what ive found has worked exceptionally well for me.

                              D Offline
                              D Offline
                              denti
                              wrote last edited by
                              #577

                              @Mr-Smurf said:

                              I've got like 26 2mg vials left. Honestly if this is it, im good with it. I've personally found them to be a ridiculously OP ancillary to some stronger stuff that I run, basically allowing me to dose that stuff lower and get an oversized effect out of it. Hopefully not a controversial take just what ive found has worked exceptionally well for me.

                              If you ever want to get rid of them I’ll take them off your hands. Of course I would reimburse you for it.

                              Mr SmurfM 1 Reply Last reply
                              0
                              • D denti

                                @Mr-Smurf said:

                                I've got like 26 2mg vials left. Honestly if this is it, im good with it. I've personally found them to be a ridiculously OP ancillary to some stronger stuff that I run, basically allowing me to dose that stuff lower and get an oversized effect out of it. Hopefully not a controversial take just what ive found has worked exceptionally well for me.

                                If you ever want to get rid of them I’ll take them off your hands. Of course I would reimburse you for it.

                                Mr SmurfM Offline
                                Mr SmurfM Offline
                                Mr Smurf
                                wrote last edited by
                                #578

                                @denti honestly not looking like its going anywhere but in my body lol my gains are surpassing what would be normal for my protocol. Im convinced combining it with aas exaggerates smaller doses into working like much larger ones would. So im getting all the good but with a very clean blood panel

                                1 Reply Last reply
                                1
                                • Mr SmurfM Offline
                                  Mr SmurfM Offline
                                  Mr Smurf
                                  wrote last edited by
                                  #579

                                  20261015_212009.jpg

                                  1 Reply Last reply
                                  2
                                  • quicksilver80Q Offline
                                    quicksilver80Q Offline
                                    quicksilver80
                                    wrote last edited by quicksilver80
                                    #580

                                    New myostatin inhibitor i saw? Holy price tag batman

                                    63ff1b58e7ab901e0925f40b1cb5af4227370f08.jpeg

                                    mmpM 1 Reply Last reply
                                    0
                                    • quicksilver80Q quicksilver80

                                      New myostatin inhibitor i saw? Holy price tag batman

                                      63ff1b58e7ab901e0925f40b1cb5af4227370f08.jpeg

                                      mmpM Online
                                      mmpM Online
                                      mmp
                                      wrote last edited by
                                      #581

                                      @quicksilver80

                                      10 mg/kg IV infusion every 4 weeks, over 60–120 minutes (max 150 mL/hour).
                                      At 10 mg/kg, a 70 kg adult needs 700 mg — 4-5 vials.

                                      1 Reply Last reply
                                      1
                                      • MacLeeezyM Offline
                                        MacLeeezyM Offline
                                        MacLeeezy
                                        wrote last edited by MacLeeezy
                                        #582

                                        In regards to the FLGR242, are you guys seeing any benefit of split dosing as opposed to one large weekly injection? I’m currently on the weekly but have been contemplating splitting it up a little when I titrate up once I hit week 9(ish)

                                        ImaFrogNotaRatI 1 Reply Last reply
                                        0
                                        • MacLeeezyM MacLeeezy

                                          In regards to the FLGR242, are you guys seeing any benefit of split dosing as opposed to one large weekly injection? I’m currently on the weekly but have been contemplating splitting it up a little when I titrate up once I hit week 9(ish)

                                          ImaFrogNotaRatI Offline
                                          ImaFrogNotaRatI Offline
                                          ImaFrogNotaRat
                                          wrote last edited by
                                          #583

                                          @MacLeeezy My biggest concern is that with the SlimAssist version of FLGR-242, if say, I want to actually use 4 mg (2 doses) at once, I'd be doubling the amount of B-vitamin too. I should have asked Mike Farber if splitting the dose, say, would even make a difference. In other words, I wonder if the modified albumin binding would also extend the longevity of the Vitamin B too. I would think not, since that is comprised of different molecules.

                                          The epigenome is malleable. Squish responsibly.

                                          D 1 Reply Last reply
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