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The "ghetto" Reta Stack. Tirz + Survo/Maz

Scheduled Pinned Locked Moved Peptide Discussion
mazdutidesurvodutideresearching
125 Posts 34 Posters 19.3k Views 15 Watching
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  • E Eleanor

    @denti A lot depends upon how old you are, how large a dose you're taking and for how long. I still have Tirz that I will be going back on later this year or early next year.

    If you're younger (I'm 70) and take a pep for years let's say, without pause or switching up, you could have problems later, IDK. Honestly, we still don't know a lot about all of these peps. For me, At 70 YOA, it doesn't really matter anymore AND, I'm taking a small dose.

    Mostly, I load Cagri to keep the food noise down from Survo. Survo has a half-life of about 6 days +. I take the Cagri a couple of days after the Survo.

    I don't know where you're getting the reconning info on Cagri but I've not heard about it. Just buy 10mg. vials; they go pretty fast and you're not throwing anything away, or tossing very little of it .

    D Offline
    D Offline
    denti
    wrote last edited by
    #116

    @Eleanor said:

    @denti A lot depends upon how old you are, how large a dose you're taking and for how long. I still have Tirz that I will be going back on later this year or early next year.

    If you're younger (I'm 70) and take a pep for years let's say, without pause or switching up, you could have problems later, IDK. Honestly, we still don't know a lot about all of these peps. For me, At 70 YOA, it doesn't really matter anymore AND, I'm taking a small dose.

    Mostly, I load Cagri to keep the food noise down from Survo. Survo has a half-life of about 6 days +. I take the Cagri a couple of days after the Survo.

    I don't know where you're getting the reconning info on Cagri but I've not heard about it. Just buy 10mg. vials; they go pretty fast and you're not throwing anything away, or tossing very little of it .

    Eleanor I don't want to link anything here, but google Cagrilintide and Amyloid Fibrils. It's what can happen to the Cagri if the PH levels are not correct and from my understanding just using Bac Water does not make it the correct PH level. So after it sits for some time, after being reconstituted the risk of fibrils developing in reconstituted Cagri increases significantly.

    E 1 Reply Last reply
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    • D denti

      @Eleanor said:

      @denti A lot depends upon how old you are, how large a dose you're taking and for how long. I still have Tirz that I will be going back on later this year or early next year.

      If you're younger (I'm 70) and take a pep for years let's say, without pause or switching up, you could have problems later, IDK. Honestly, we still don't know a lot about all of these peps. For me, At 70 YOA, it doesn't really matter anymore AND, I'm taking a small dose.

      Mostly, I load Cagri to keep the food noise down from Survo. Survo has a half-life of about 6 days +. I take the Cagri a couple of days after the Survo.

      I don't know where you're getting the reconning info on Cagri but I've not heard about it. Just buy 10mg. vials; they go pretty fast and you're not throwing anything away, or tossing very little of it .

      Eleanor I don't want to link anything here, but google Cagrilintide and Amyloid Fibrils. It's what can happen to the Cagri if the PH levels are not correct and from my understanding just using Bac Water does not make it the correct PH level. So after it sits for some time, after being reconstituted the risk of fibrils developing in reconstituted Cagri increases significantly.

      E Offline
      E Offline
      Eleanor
      wrote last edited by
      #117

      @denti I suppose then the question is: How much time before the fibrils develop? This is why I said to get 10mg vial, as if you're that cautious, there's little left to toss out.

      Proud to be on a gubmint watch list

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        D Offline
        denti
        wrote last edited by
        #118

        I can't recall off the top of my head but I remember reading on another forum that it was as quick as 7 days it could develop. I had purchased 10mg kit from Nexaph before I read about all this, and reconned 1 vial and started at 0.5mg as my first dose, and then read about it all, and decided to throw away the rest of the 9.5mg that was left before my next dose a week later as I was worried about it. I would like to use Cagri for the appetite suppressant as I am ready to be done with Reta, but this Fibrils issue worries me too much. That's why I was thinking if I do try it again, I will just recon, inject and throw away the rest of the vial. I see Nexaph sells 5mg vial which would be less waste for me than the 10mg ones I have.

        Hence my interest of going solely on Survo after coming off Reta, but if I am going to have the cravings you are referring to, I don't think that will work for me alone either. And adding Cagri would be beneficial then.

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          E Offline
          Eleanor
          wrote last edited by
          #119

          5 mg. a good idea then.

          Proud to be on a gubmint watch list

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          • E Eleanor

            @denti I suppose then the question is: How much time before the fibrils develop? This is why I said to get 10mg vial, as if you're that cautious, there's little left to toss out.

            E Offline
            E Offline
            Eleanor
            wrote last edited by
            #120

            @denti
            Been reading about fibrils and can develop at any time; either upon recon or any time afterward. If the solution looks even slightly discolored, I'll toss it. Otherwise, the instructions are to reconstitute like others; might want to be a bit more gentle with this one is all I can do.

            Proud to be on a gubmint watch list

            pep_researcherP 1 Reply Last reply
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            • E Eleanor

              @denti
              Been reading about fibrils and can develop at any time; either upon recon or any time afterward. If the solution looks even slightly discolored, I'll toss it. Otherwise, the instructions are to reconstitute like others; might want to be a bit more gentle with this one is all I can do.

              pep_researcherP Offline
              pep_researcherP Offline
              pep_researcher
              wrote last edited by
              #121

              @Eleanor I had a long chat regarding this fibril hypothesis with an AI chatbot. It confirmed repeatedly that this fibrillation concern is for native endogenous amylin not for synthetically generated molecule like Cagri.

              Just FYI if it helps.

              E 1 Reply Last reply
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              • pep_researcherP pep_researcher

                @Eleanor I had a long chat regarding this fibril hypothesis with an AI chatbot. It confirmed repeatedly that this fibrillation concern is for native endogenous amylin not for synthetically generated molecule like Cagri.

                Just FYI if it helps.

                E Offline
                E Offline
                Eleanor
                wrote last edited by
                #122

                @pep_researcher said:

                @Eleanor I had a long chat regarding this fibril hypothesis with an AI chatbot. It confirmed repeatedly that this fibrillation concern is for native endogenous amylin not for synthetically generated molecule like Cagri.

                Just FYI if it helps.

                Yes, that's what the conversation said when I chatted too. I don't think it's a problem either, but if enough discoloration shows up, well, it might be a hint something is going on. It's never turned on me before, so not really worried. Thanks for the confirmation.

                Proud to be on a gubmint watch list

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                • Mydogdaryl423M Mydogdaryl423 referenced this topic
                • RandyR Randy

                  depends on how sensitive the rat is to the glp.

                  Right now im ripping 15 tirz and 3.5 survo 3 days apart

                  B Offline
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                  brentlong
                  wrote last edited by
                  #123

                  @Randy said:

                  depends on how sensitive the rat is to the glp.

                  Right now im ripping 15 tirz and 3.5 survo 3 days apart

                  @Randy are you still at 15 tirz and 3.5 survo? Im asking because wife has hit a stall on 15 tirz and came across a post of yours to day and ended up here. Where should she start at with the survo?

                  mmpM 1 Reply Last reply
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                  • B brentlong

                    @Randy said:

                    depends on how sensitive the rat is to the glp.

                    Right now im ripping 15 tirz and 3.5 survo 3 days apart

                    @Randy are you still at 15 tirz and 3.5 survo? Im asking because wife has hit a stall on 15 tirz and came across a post of yours to day and ended up here. Where should she start at with the survo?

                    mmpM Online
                    mmpM Online
                    mmp
                    wrote last edited by mmp
                    #124

                    @brentlong
                    I would add cagrilintide/eloralintide or switch to reta

                    93d60500-3ee2-4b82-b5fa-e122f8df9930-image.jpeg

                    B 1 Reply Last reply
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                    • mmpM mmp

                      @brentlong
                      I would add cagrilintide/eloralintide or switch to reta

                      93d60500-3ee2-4b82-b5fa-e122f8df9930-image.jpeg

                      B Offline
                      B Offline
                      brentlong
                      wrote last edited by
                      #125

                      @mmp said:

                      @brentlong
                      I would add cagrilintide/eloralintide or switch to reta

                      93d60500-3ee2-4b82-b5fa-e122f8df9930-image.jpeg

                      @mmp thank you!!

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