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  3. If reta exists, why do you still research sema or tirz?
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If reta exists, why do you still research sema or tirz?

Scheduled Pinned Locked Moved Peptide Discussion
glp1-sglp2-tglp3-r
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  • ResearchCatR ResearchCat

    Some people have reactions or side effects with reta, and a lot of people have better appetite and other desire suppression with Tirz. I am on the lowest dose of Tirz and don’t see a particularly compelling reason to switch. I might at some point.

    When NA-931 becomes available, I will be all over that.

    B Offline
    B Offline
    brandenscheidecker
    wrote last edited by
    #4

    @ResearchCat said in If reta exists, why do you still research sema or tirz?:

    Some people have reactions or side effects with reta, and a lot of people have better appetite and other desire suppression with Tirz. I am on the lowest dose of Tirz and don’t see a particularly compelling reason to switch. I might at some point.

    When NA-931 becomes available, I will be all over that.

    https://dreampharmastore.com/product/bioglutide-na-931/

    1.5 mg $639.30

    afkar7A 1 Reply Last reply
    2
    • ResearchCatR ResearchCat

      Some people have reactions or side effects with reta, and a lot of people have better appetite and other desire suppression with Tirz. I am on the lowest dose of Tirz and don’t see a particularly compelling reason to switch. I might at some point.

      When NA-931 becomes available, I will be all over that.

      pep_researcherP Offline
      pep_researcherP Offline
      pep_researcher
      wrote last edited by
      #5

      @ResearchCat said in If reta exists, why do you still research sema or tirz?:

      NA-931

      Ooh that's a new one I didn't know about. 🙂

      1 Reply Last reply
      1
      • quicksilver80Q Online
        quicksilver80Q Online
        quicksilver80
        wrote last edited by
        #6

        it will be the same conversation when trevogrumab and garetasumab gets into the hands of gymfluencers. or another example is thatt quintuple agonist that was announced at ada 2026. and so on and so on lol

        1 Reply Last reply
        2
        • ResearchCatR Offline
          ResearchCatR Offline
          ResearchCat
          wrote last edited by
          #7

          @brandenscheidecker Oh wow. I didn’t think it was far enough along for anyone to be making it. Thx!

          Yeah, well, I’m just here for the research, man. - The Dude

          If I haven’t liked your post, no offense. I have exceeded my daily allowance.

          1 Reply Last reply
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          • B brandenscheidecker

            @ResearchCat said in If reta exists, why do you still research sema or tirz?:

            Some people have reactions or side effects with reta, and a lot of people have better appetite and other desire suppression with Tirz. I am on the lowest dose of Tirz and don’t see a particularly compelling reason to switch. I might at some point.

            When NA-931 becomes available, I will be all over that.

            https://dreampharmastore.com/product/bioglutide-na-931/

            1.5 mg $639.30

            afkar7A Offline
            afkar7A Offline
            afkar7
            wrote last edited by
            #8

            @brandenscheidecker said in If reta exists, why do you still research sema or tirz?:

            1.5 mg $639.30

            Daaaammmmnnn

            1 Reply Last reply
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            • ResearchCatR Offline
              ResearchCatR Offline
              ResearchCat
              wrote last edited by
              #9

              I don’t even know what to do with that. The research I have seen is done with 120-150mg taken orally on a daily basis.

              Yeah, well, I’m just here for the research, man. - The Dude

              If I haven’t liked your post, no offense. I have exceeded my daily allowance.

              1 Reply Last reply
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              • ResearchCatR ResearchCat

                Some people have reactions or side effects with reta, and a lot of people have better appetite and other desire suppression with Tirz. I am on the lowest dose of Tirz and don’t see a particularly compelling reason to switch. I might at some point.

                When NA-931 becomes available, I will be all over that.

                mrjoshua44M Online
                mrjoshua44M Online
                mrjoshua44
                wrote last edited by
                #10

                @ResearchCat I’m right there with ya. Been on compounded Tirzepatide since December, was on 2.125 mg for three and a half months before I moved up to 4.25 mg, that I’m still on today. I’ve lost 61 lbs with Tirzepatide and like you, see no reason to switch to Reta.

                1 Reply Last reply
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                • Stan DouglasS Offline
                  Stan DouglasS Offline
                  Stan Douglas
                  wrote last edited by
                  #11

                  Long Story: My doctor put me on Zepbound [tirz] 2.5, Started getting hungry after 6 weeks so she bumped it to 5mg. I've maintained a 2lb. a week loss for 3 months.
                  I've taken my last Zep today and have 5 Triz in my freezer right now because it is 1/5 the price. At this rate, assuming I stay at 5mg per week, I should hit my goals.
                  I'll ween myself off the last few weeks, see how I do. If I need a maintenance dose I'll give Reta a try.

                  Short Story: I started on Triz and it's been working for me.

                  1 Reply Last reply
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                  • ResearchCatR Offline
                    ResearchCatR Offline
                    ResearchCat
                    wrote last edited by
                    #12

                    That’s awesome! I am glad to hear your success stories with Tirzepatide!

                    Yeah, well, I’m just here for the research, man. - The Dude

                    If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                    1 Reply Last reply
                    0
                    • B Offline
                      B Offline
                      Bil
                      wrote last edited by
                      #13

                      I started on Tirz in Oct, down 85lbs and hit a stall at 15mg that I've been stuck at for 2 months. Reading through the forum I saw Randy’s “ghetto” Reta stack and decided to give that a try. Going to add 2mg of Maz to see if I can break through it. Will try Reta, if all else fails but have been super happy with the Tirz.

                      pep_researcherP 1 Reply Last reply
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                      • C Offline
                        C Offline
                        cami
                        wrote last edited by
                        #14

                        I saw that increased heart rate was a known side effect of reta, and I already have anxiety to do that for me. 🙂 I'm on week 4 of tirz now and feel great, so I'm not interested in stopping it anytime soon!

                        1 Reply Last reply
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                        • B Bil

                          I started on Tirz in Oct, down 85lbs and hit a stall at 15mg that I've been stuck at for 2 months. Reading through the forum I saw Randy’s “ghetto” Reta stack and decided to give that a try. Going to add 2mg of Maz to see if I can break through it. Will try Reta, if all else fails but have been super happy with the Tirz.

                          pep_researcherP Offline
                          pep_researcherP Offline
                          pep_researcher
                          wrote last edited by
                          #15

                          @Bil said in If reta exists, why do you still research sema or tirz?:

                          I started on Tirz in Oct, down 85lbs and hit a stall at 15mg that I've been stuck at for 2 months. Reading through the forum I saw Randy’s “ghetto” Reta stack and decided to give that a try. Going to add 2mg of Maz to see if I can break through it. Will try Reta, if all else fails but have been super happy with the Tirz.

                          Have you or anyone tried Tirz + Survo stack? AI chats say Survo binds to Glucagon stronger than Reta and the latest phase 3 results I think show that although net percent weight loss might be lower Survo selectively torches fat through glucagon agonism and tends to spare muscles better. Which sounds quite good.

                          B RandyR 2 Replies Last reply
                          1
                          • pep_researcherP Offline
                            pep_researcherP Offline
                            pep_researcher
                            wrote last edited by
                            #16

                            And price and dosing wise Survo tends to be a lot cheaper than Maz.

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                            • E Offline
                              E Offline
                              emkay
                              wrote last edited by
                              #17

                              I researched both and ended up back where I started with tirz, less inflammation and autoimmune pain, better focus from lack of food noise.

                              1 Reply Last reply
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                              • S Offline
                                S Offline
                                Splinter
                                wrote last edited by
                                #18

                                Thanks for all the responses. Learning about upcoming compounds makes sense why people will be comfortable with what they’re finding success with.

                                I understand cause I’m happy with Reta, and don’t see a need to mess with na-931 😅

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                                • pep_researcherP pep_researcher

                                  @Bil said in If reta exists, why do you still research sema or tirz?:

                                  I started on Tirz in Oct, down 85lbs and hit a stall at 15mg that I've been stuck at for 2 months. Reading through the forum I saw Randy’s “ghetto” Reta stack and decided to give that a try. Going to add 2mg of Maz to see if I can break through it. Will try Reta, if all else fails but have been super happy with the Tirz.

                                  Have you or anyone tried Tirz + Survo stack? AI chats say Survo binds to Glucagon stronger than Reta and the latest phase 3 results I think show that although net percent weight loss might be lower Survo selectively torches fat through glucagon agonism and tends to spare muscles better. Which sounds quite good.

                                  B Offline
                                  B Offline
                                  Bil
                                  wrote last edited by
                                  #19

                                  @pep_researcher I have not tried the Tirz+ Survo stack, but thats the next option. The muscle sparing is interesting I’ll have to look into that more. I went with the Maz because it was the smoother stack as far as appetite suppression. I got enough to research for 2 months, if I haven’t hit my goals will reset and research the Survo.

                                  1 Reply Last reply
                                  0
                                  • S Offline
                                    S Offline
                                    space
                                    wrote last edited by
                                    #20

                                    Why not research combinations? Triz did not have the appetite suppression at moderate dosage I was looking for. Everything else was great, so a small dose of Sema picks up the slack.

                                    1 Reply Last reply
                                    0
                                    • C Commander

                                      I think that every time I read a post about Tirz..

                                      Sable DarqnessS Offline
                                      Sable DarqnessS Offline
                                      Sable Darqness
                                      wrote last edited by
                                      #21

                                      @Commander i Stay on Mounjaro (Tirz) because with my insurance my 10mg 4 pen set costs me only $25

                                      1 Reply Last reply
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                                      • quicksilver80Q Online
                                        quicksilver80Q Online
                                        quicksilver80
                                        wrote last edited by
                                        #22

                                        no appetite what so ever on reta. personally dont need any more help in that department. which i have pretty much all the glp1s easily available. but never seen the need? thats why ive been looking into stuff like gh, mots, mitochondria uncouplers and ampk modulators. like bam and atx304 etc. then the real final frontier is when i can see more first hand accounts with the trevogrumab/garetasumab combo. i need the muscle gain to match the fat loss. 40 more pounds to go and im not asking anymore

                                        1 Reply Last reply
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                                        • S Splinter

                                          As the subject states.

                                          If Reta exists and is the best, why does anyone buying grey still mess with sema or tirz?

                                          RandyR Offline
                                          RandyR Offline
                                          Randy
                                          wrote last edited by
                                          #23

                                          @Splinter reta doesnt calm food noise as well as tirz. Its not "better" it's different...they also documented more muscle wasting with reta towards the end of the last trial.

                                          Theyre both great but milage may vary

                                          "If it doesnt come in a needle. It doesn't work"

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