Tesa vs CJC?
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@vpeptides The advantage is that you’re not wasting your peptide. If you weren’t researching Reta at the same time I would stick with pinning at night to take advantage of the natural HGH release.
How does reta impact natural HGH (assuming you pin 2+ hours after your last meal)?
@derekg1 Reta slows gastric emptying but it isn't anything crazy, The standard recomendation is for optimal results two hours fasted before bed, with a GLP on board 3 hours. The extra hour more than covers the slower gastric emptying on Reta.
Plus its a good idea without GHRH or GHRPS to make this a habbit. Its well documented that 3 hour fast alone is enough to improve sleep, recovery and metabolism.
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I believe the issue is blood sugars, when they're elevated it contributes to somatostatin which is the growth hormone blocking hormone. Some people will fast and still have high blood sugars from having some insulin resistance, which imo needs to be addressed so that we're not getting water retention and carpal tunnel sides without the benefits.
With reta if you're still digesting dinner after 2 hours your blood sugars will still be elevated.
I'm currently working on getting my fasting blood sugars routinely 90 or under before I start gh or gh releasers. for what it's worth I'm still trying to figure alot of peptide information out and I may be off base but hopefully it adds to the discussion
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It’s the GHRH competing with insulin. Insulin blunts the GHRH effectiveness. I have been researching in the morning right when I get up and then don’t eat for 1-2 hours after. Seems to work fine and guarantees you’re fasted. I can’t fast 3 hours before bed.
Edited to be more accurate.
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@mfadden99 And it makes your face warm so you know its working!
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Just finished a test vial of Tesa after running CJC/IPA for 12 weeks. Had 10mg from a friend so decided to run 5 day course of the vial. No flushing like CJC (as mentioned above), but after 3rd day, joints started to hurt a bit and scale up 3-4 pounds from water retention. Wasn't a fan...CJC it is for me.....well....GH, really...
If you're headed somewhere, just go there...
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Just finished a test vial of Tesa after running CJC/IPA for 12 weeks. Had 10mg from a friend so decided to run 5 day course of the vial. No flushing like CJC (as mentioned above), but after 3rd day, joints started to hurt a bit and scale up 3-4 pounds from water retention. Wasn't a fan...CJC it is for me.....well....GH, really...
If you're headed somewhere, just go there...
Just finished a test vial of Tesa after running CJC/IPA for 12 weeks. Had 10mg from a friend so decided to run 5 day course of the vial. No flushing like CJC (as mentioned above), but after 3rd day, joints started to hurt a bit and scale up 3-4 pounds from water retention. Wasn't a fan...CJC it is for me.....well....GH, really...
If you're headed somewhere, just go there...
2mg is way too high of a newbie starter dose. You should have gone 1mg. Also, the water retention and joint issues is a by product of high GH......which means it was working.
If you're so susceptible of side effects from GH that 2mg of Tesa gave you joint pain and water retention within the first week, even something as small as 1iu of HGH is likely going to do the same thing.
What is your baseline igf-1 level that you're going from?
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It’s the GHRH competing with insulin. Insulin blunts the GHRH effectiveness. I have been researching in the morning right when I get up and then don’t eat for 1-2 hours after. Seems to work fine and guarantees you’re fasted. I can’t fast 3 hours before bed.
Edited to be more accurate.
@ResearchCat My dumb question of the morning. Since I typically don't eat in the morning either, I'm leaning towards morning doses when I start my cycle. With that said, i do usually have a protein drink and fiber drink in the morning. While not eating per se, should I delay them for a couple of hours if I decide on the morning protocol? I suspect so, but don't want to overthink it. Thanks for any imput.
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Just finished a test vial of Tesa after running CJC/IPA for 12 weeks. Had 10mg from a friend so decided to run 5 day course of the vial. No flushing like CJC (as mentioned above), but after 3rd day, joints started to hurt a bit and scale up 3-4 pounds from water retention. Wasn't a fan...CJC it is for me.....well....GH, really...
If you're headed somewhere, just go there...
2mg is way too high of a newbie starter dose. You should have gone 1mg. Also, the water retention and joint issues is a by product of high GH......which means it was working.
If you're so susceptible of side effects from GH that 2mg of Tesa gave you joint pain and water retention within the first week, even something as small as 1iu of HGH is likely going to do the same thing.
What is your baseline igf-1 level that you're going from?
@Neil-McCauley Thought process was that I had been running what was considered standard for CJC/IPA for 3 mo prior. IGF-1 at 140.
I plan on starting GH at 1iu
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@ResearchCat My dumb question of the morning. Since I typically don't eat in the morning either, I'm leaning towards morning doses when I start my cycle. With that said, i do usually have a protein drink and fiber drink in the morning. While not eating per se, should I delay them for a couple of hours if I decide on the morning protocol? I suspect so, but don't want to overthink it. Thanks for any imput.
@coondogesq As I understand it, anything that breaks the fast will increase insulin, stunting the GH pulse. It seems generally accepted for either morning or night dose to do on empty stomach and delay eating for 1-2hr.
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@ResearchCat My dumb question of the morning. Since I typically don't eat in the morning either, I'm leaning towards morning doses when I start my cycle. With that said, i do usually have a protein drink and fiber drink in the morning. While not eating per se, should I delay them for a couple of hours if I decide on the morning protocol? I suspect so, but don't want to overthink it. Thanks for any imput.
@coondogesq Yes because as soon as you put any calories in your mouth the fast ends and insulin spikes.
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Agreed with @hunt_ak and @shaqdiesel. I will drink black coffee but no calories for 1-2 hours afterwards. And yeah, it’s usually a protein shake and my creatine/fiber blend. Opinions vary but most people agree somewhere in the 1-2 hours range is fine, since the GH pulse will likely be shorter than that. Some folks (I think Randy has said) using GH or Tesa have said they fast as long as they can, but they are also doing intermittent fasting and weren’t planning to eat anyway.
My challenge - and for many GLP-1 users - is to balance optimal preparation for peptide protocols with the need to onboard macros at target levels. And as stated previously, fasting for 3 hours before bed just isn’t possible for me without falling short of my macros.
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@ResearchCat My dumb question of the morning. Since I typically don't eat in the morning either, I'm leaning towards morning doses when I start my cycle. With that said, i do usually have a protein drink and fiber drink in the morning. While not eating per se, should I delay them for a couple of hours if I decide on the morning protocol? I suspect so, but don't want to overthink it. Thanks for any imput.
@ResearchCat My dumb question of the morning. Since I typically don't eat in the morning either, I'm leaning towards morning doses when I start my cycle. With that said, i do usually have a protein drink and fiber drink in the morning. While not eating per se, should I delay them for a couple of hours if I decide on the morning protocol? I suspect so, but don't want to overthink it. Thanks for any imput.
Go the full 2 hours if you can. The GH boost is primarily within the first 60 minutes post pin, but there is a transient amount in that second hour that ideally you want to take advantage of.
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Appreciate everyone confirming my presumptions.
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Just finished a test vial of Tesa after running CJC/IPA for 12 weeks. Had 10mg from a friend so decided to run 5 day course of the vial. No flushing like CJC (as mentioned above), but after 3rd day, joints started to hurt a bit and scale up 3-4 pounds from water retention. Wasn't a fan...CJC it is for me.....well....GH, really...
If you're headed somewhere, just go there...
2mg is way too high of a newbie starter dose. You should have gone 1mg. Also, the water retention and joint issues is a by product of high GH......which means it was working.
If you're so susceptible of side effects from GH that 2mg of Tesa gave you joint pain and water retention within the first week, even something as small as 1iu of HGH is likely going to do the same thing.
What is your baseline igf-1 level that you're going from?
@Neil-McCauley This is great advice. I stopped taking Tesa because of the side effects, and I was researching the recommended 2mg/day. It didn’t really occur to me to drop to 1mg, at least partially because I planned to switch back to CJC/Ipa. If I was committed to Tesa, that would have been a good idea.
I have researched Sermorelin and CJC/Ipa previously and neither caused the side effects that Tesa did. Not sure if it was purely dosing or specific to the peptide. My Sermorelin dosing was probably conservative, CJC/Ipa normal to slightly aggressive, and 2mg for Tesa, which is possibly too high.
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Hoping to get assistant for my research subject. If I watch Josh’s video he’s leaving towards CJC for price and similar effect?
@jborja @researchcat @commander I don't get this I know Tesa is supposed to stimulate growth hormone, but the research is on abdominal fat in AIDS patients. I use CJC/IPA and saw all of my testosterone levels increase on my monthly blood testing, so I have factual proof it works. I take it at night, probably never more than 2 -3 hours fasted. SHBG up 29% to optimal, Free up 36% to optimal, and total up 43% to 874, also optimal. The proof is in the blood work. For whatever reason, my Estrogen is my only marker that is not average or optimal. It may be related to recovery, sleep, and stress. I can't listen to Josh with his cocky I know everything because I am tatted up, steroid abuser. I think he actually knows less than most of us on here. Why he hasn't been shut down makes no sense.
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@jborja @researchcat @commander I don't get this I know Tesa is supposed to stimulate growth hormone, but the research is on abdominal fat in AIDS patients. I use CJC/IPA and saw all of my testosterone levels increase on my monthly blood testing, so I have factual proof it works. I take it at night, probably never more than 2 -3 hours fasted. SHBG up 29% to optimal, Free up 36% to optimal, and total up 43% to 874, also optimal. The proof is in the blood work. For whatever reason, my Estrogen is my only marker that is not average or optimal. It may be related to recovery, sleep, and stress. I can't listen to Josh with his cocky I know everything because I am tatted up, steroid abuser. I think he actually knows less than most of us on here. Why he hasn't been shut down makes no sense.
@Stevepep as far as I understood the GHRH analogs (CJC/IPA like you mention) are going to pulse GH, telling your liver to produce IGF-1. An increase in IGF-1 production shouldn't have a correlation to testosterone production.
Am I missing something here? Seems to be two different conversations.
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@Stevepep as far as I understood the GHRH analogs (CJC/IPA like you mention) are going to pulse GH, telling your liver to produce IGF-1. An increase in IGF-1 production shouldn't have a correlation to testosterone production.
Am I missing something here? Seems to be two different conversations.
@hunt_ak it stimulates the pituitary gland to produce growth hormone. There are actually a couple of videos of people getting blood work after 30 and 60 days who had similar results to me. Everyone is different in terms of exercise, diet, sleep etc so results will always vary but it worked miracles for me. I am in my 50’s my rythm score is over 90 and my biological age is 14 years younger on my Rythm blood test. I just can’t forgive out the one market, estrogen that is off.
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@Stevepep as far as I understood the GHRH analogs (CJC/IPA like you mention) are going to pulse GH, telling your liver to produce IGF-1. An increase in IGF-1 production shouldn't have a correlation to testosterone production.
Am I missing something here? Seems to be two different conversations.
@hunt_ak it stimulates the pituitary gland to produce growth hormone. There are actually a couple of videos of people getting blood work after 30 and 60 days who had similar results to me. Everyone is different in terms of exercise, diet, sleep etc so results will always vary but it worked miracles for me. I do the rhythm blood test every 30 days to track results. It’s the only way to verify what’s working and what’s not or what may be having a negative effect. Otherwise I feel like you are using peptides in the blind. Dexa is a good indicator as well. I just tested telomeres as I am going to start Epitalon waiting on those results and then I will test once the cycle is done to see if there was any improvement.
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