Switching from reta (GLP3-r) to Nexaph tirz (glp2-2)
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Hey all, a bit concerned. I purchased a batch of tirzepatide from Nexaph about mid-April after having been on reta for about 2 months without issues except some palpitations so I thought I would give tirz a try. I know it's not apples to apples, but I was on 4 mg of reta when I switched and started on 2mg of tirz and thought I must have picked up a stomach bug (going around) because the runs were insane for 3-4 days and I didn't really feel any appetite changes like I did on reta, so I thought just a fluke. Took the 2nd week dose a day early and I'm completely TORE UP. 20-30x/day for the last 2 days. Anyway, I looked at Finnrick and noticed that for tirzepatide, Nexaph got a pretty low grade, E. The most recent batches seemed to score ok, except a couple sent in early March that didn't do well. Mine was batched on 3/28/26 and I got the blue cap/blue crimp 60mg vials.
Just wondering if anyone out there has
- Has had similar experiences with switching from reta to tirz?
- Has anyone had trouble with tirz from Nexaph recently?
Any input much appreciated
. I know I could just send off a vial to Finnrick. Just wondering if it's worth it or if it's just me -
My wife gets their glp2 and I get their glp3. She says it doesn’t seem as strong as other glp2 she had used. But the glp3 has been great for me.
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Hey all, a bit concerned. I purchased a batch of tirzepatide from Nexaph about mid-April after having been on reta for about 2 months without issues except some palpitations so I thought I would give tirz a try. I know it's not apples to apples, but I was on 4 mg of reta when I switched and started on 2mg of tirz and thought I must have picked up a stomach bug (going around) because the runs were insane for 3-4 days and I didn't really feel any appetite changes like I did on reta, so I thought just a fluke. Took the 2nd week dose a day early and I'm completely TORE UP. 20-30x/day for the last 2 days. Anyway, I looked at Finnrick and noticed that for tirzepatide, Nexaph got a pretty low grade, E. The most recent batches seemed to score ok, except a couple sent in early March that didn't do well. Mine was batched on 3/28/26 and I got the blue cap/blue crimp 60mg vials.
Just wondering if anyone out there has
- Has had similar experiences with switching from reta to tirz?
- Has anyone had trouble with tirz from Nexaph recently?
Any input much appreciated
. I know I could just send off a vial to Finnrick. Just wondering if it's worth it or if it's just me@mattclayton Palpitations is crazy.. Why not lower your dose tho? This was on R3 from Nexa?
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@mattclayton Palpitations is crazy.. Why not lower your dose tho? This was on R3 from Nexa?
@Foodstampede my ts had some heart races when waking up abruptly. also at the gym but i chalked that up to anxiety. on reta. 6mg pulled back to 4 an dropped its caffiene intake and it went away. it reacts way differently to caffiene after being on for months. research says its not uncommon.
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Reta was from Nexa?
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@mattclayton Palpitations is crazy.. Why not lower your dose tho? This was on R3 from Nexa?
@Foodstampede it was hurting my sleep, which is already horrible, on 1mg. On 2mg, I was sleeping 3-4 hours a night and working 12-14 hour days. No sleep predisposes me to a.fib (for the last couple years). This was just a trigger, even on 1-2mg. Now that I am on DSIP and lunesta tho, it might be better if I moved back
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@mattclayton Palpitations is crazy.. Why not lower your dose tho? This was on R3 from Nexa?
@Foodstampede it was hurting my sleep, which is already horrible, on 1mg. On 2mg, I was sleeping 3-4 hours a night and working 12-14 hour days. No sleep predisposes me to a.fib (for the last couple years). This was just a trigger, even on 1-2mg. Now that I am on DSIP and lunesta tho, it might be better if I moved back
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Reta was from Nexa?
@Foodstampede no, from another pricier vendor. Independently tested. It was good. I have some reta from Nexa tho...
