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  1. Randy the Rats Research Forum
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  3. Semax Spray nose bleed
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Semax Spray nose bleed

Scheduled Pinned Locked Moved Peptide Discussion
semaxside-effects
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  • R Offline
    R Offline
    rarobl27
    wrote last edited by
    #1

    Reconstituted 10mg Semax with 2 ml BAC added to 5ml 0.9% saline in a sterile amber bottle, then refrigerated to use next day. My rat did a couple sprays the next day and got a nose bleed later in the day. At first didn’t blame it on the spray since it’s been pretty hot out and it’s not stranger to it happening. Tried it again a couple more days and same bleeding happened both days, then stopped for a day and no nosebleed. Tried subcutaneous before without any issues. Bummed out because my rat was excited about the spray option working faster/alternate deliver method.

    Has anybody had this happen before?

    Jake_PepTronJ 1 Reply Last reply
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    • Snake PepskinS Online
      Snake PepskinS Online
      Snake Pepskin
      wrote last edited by Snake Pepskin
      #2

      It’s likely because the alcohol in the BAC. If you have sensitive nasal passages, it happens. I used as little BAC as possible. Some actually recon with the saline, although I haven’t tried that.

      One of my nasal spray bottles I sterilized with alcohol, and apparently I didn’t get all of it out before I filled it. The first time I used it, same thing happened.

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      • R Offline
        R Offline
        ResearchCat
        wrote last edited by
        #3

        I get nosebleeds a lot and have been using Semax nasal spray for a few months. I have not noticed that I get them more frequently than before. I mainly need to be mindful of when the air is dry and/or cold. I can’t eliminate it as an aggravator but in my case, it doesn’t seem to make it much worse.

        Please set a funny and sarcastic signature line. It brings me joy. Thank you for your attention in this matter.

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        • R rarobl27

          Reconstituted 10mg Semax with 2 ml BAC added to 5ml 0.9% saline in a sterile amber bottle, then refrigerated to use next day. My rat did a couple sprays the next day and got a nose bleed later in the day. At first didn’t blame it on the spray since it’s been pretty hot out and it’s not stranger to it happening. Tried it again a couple more days and same bleeding happened both days, then stopped for a day and no nosebleed. Tried subcutaneous before without any issues. Bummed out because my rat was excited about the spray option working faster/alternate deliver method.

          Has anybody had this happen before?

          Jake_PepTronJ Offline
          Jake_PepTronJ Offline
          Jake_PepTron
          wrote last edited by Jake_PepTron
          #4

          @rarobl27 never had nosebleed issues with nasal selank or semax before. However, my research rat only reconstitutes with the 0.9% sterile-saline, no BAC. For a cheap experiment, maybe try using ONLY the sterile-saline in the spray-bottle and see if you still get nosebleeds. If so, then you may just have very sensitive nasal passages. If not, then try reconstituting semax with just the saline and see how ya feel.

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          • R Offline
            R Offline
            rarobl27
            wrote last edited by
            #5

            Thanks for all the feedback everyone! I was suspecting the alcohol in the BAC as well, my rat does get nosebleeds a lot with the hot/cold air but this was every single time the spray was used. Going to try the saline only recommendation and see what happens, glad I waited to reconstitute my selank! Thanks again

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