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Pinealon

Scheduled Pinned Locked Moved Peptide Discussion
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  • S Offline
    S Offline
    Stevepep
    wrote last edited by
    #1

    What is the suggested protocol. Just got confused by other posts. @randy you love it please chime in. I am titrating starting at 1mg up to 5 for the last 5 days for 20 days total. Just started

    pep_researcherP 1 Reply Last reply
    0
    • S Offline
      S Offline
      Shaqdiesel
      wrote last edited by
      #2

      I did 2.5mgs for 20 days. I think that may be a little high from what I've seen but it did great for me.

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      • M Offline
        M Offline
        matthewwalsh
        wrote last edited by
        #3

        I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

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        • vpeptidesV Online
          vpeptidesV Online
          vpeptides
          wrote last edited by vpeptides
          #4

          Research on Pinealon used doses from 200mcg with 500mcg suggested as more effective, and patient-specific optimizations up to 3.5mg.
          If taken orally or intranasally it is also usually split to 2-3 doses a day.
          Toxicology studies in pigs showed no organ damage even at 1,000 times the normal dose. Still, high doses can sometimes cause sleepiness, low blood sugar, or mood shifts.
          High doses are around 0.1mg/kg, ~9mg for 200lb.

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          • M matthewwalsh

            I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

            S Offline
            S Offline
            Shaqdiesel
            wrote last edited by
            #5

            @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

            vpeptidesV M 2 Replies Last reply
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            • S Shaqdiesel

              @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

              vpeptidesV Online
              vpeptidesV Online
              vpeptides
              wrote last edited by
              #6

              @Shaqdiesel Epitalon is tricky. Next time you may try for an experiment for one or two nights use 0.1-0.2mg. 0.1mg is enough for melatonin production, and over 0.6mg for some may have the opposite effect.

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              • vpeptidesV vpeptides

                @Shaqdiesel Epitalon is tricky. Next time you may try for an experiment for one or two nights use 0.1-0.2mg. 0.1mg is enough for melatonin production, and over 0.6mg for some may have the opposite effect.

                S Offline
                S Offline
                Shaqdiesel
                wrote last edited by
                #7

                @vpeptides I did the previous cycle of both before bed. My REM improved a lot along with memory and cognition. I am tempted to change to morning dosing next time per I believe @gym.rat suggestion with morning sunshine.

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                • S Offline
                  S Offline
                  Stevepep
                  wrote last edited by Stevepep
                  #8

                  Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

                  vpeptidesV gym.ratG 2 Replies Last reply
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                  • S Stevepep

                    Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

                    vpeptidesV Online
                    vpeptidesV Online
                    vpeptides
                    wrote last edited by vpeptides
                    #9

                    @Stevepep The reason is that the original studies, those sites draw the conclusion from, were performed not on epitalon, but on epitalamine - a pineal extract, which contained epitalon at maybe around 5%.
                    For Epitalon studies tested doses 1,000-5,000 times higher than human doses without finding toxic effects. So, they may overshoot but there is no harm.
                    0.1mg is enough for melatonin production, but the high doses may have additional effects too. It is likely that for telomerase production or for broader anti-aging or therapeutic goals you may use up to 5-10mg daily.

                    1 Reply Last reply
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                    • S Shaqdiesel

                      @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

                      M Offline
                      M Offline
                      matthewwalsh
                      wrote last edited by
                      #10

                      @Shaqdiesel Thank you!

                      1 Reply Last reply
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                      • E Online
                        E Online
                        Eleanor
                        wrote last edited by
                        #11

                        @shaqdiesel Are you pinning Epitalon and Pinealon same time, same of day, or other?

                        1 Reply Last reply
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                        • S Offline
                          S Offline
                          Shaqdiesel
                          wrote last edited by
                          #12

                          @eleanor Same time but different pins. I do not mix them.

                          E 1 Reply Last reply
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                          • M matthewwalsh

                            I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

                            T Online
                            T Online
                            TBone
                            wrote last edited by
                            #13

                            @matthewwalsh I’m just finishing 25 days at 2mg per day. Just prior to that I researched 5mg of Epithalon per day for 20 days. Can’t say I noticed anything different with either. And actually, my sleep has been worse during these cycles. 😕

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                            • S Stevepep

                              What is the suggested protocol. Just got confused by other posts. @randy you love it please chime in. I am titrating starting at 1mg up to 5 for the last 5 days for 20 days total. Just started

                              pep_researcherP Offline
                              pep_researcherP Offline
                              pep_researcher
                              wrote last edited by pep_researcher
                              #14

                              @Stevepep search function is very useful here. 😉

                              https://community.peptidecritic.com/post/5042

                              FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                              E 1 Reply Last reply
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                              • judgetooJ Online
                                judgetooJ Online
                                judgetoo
                                wrote last edited by
                                #15

                                We followed Nick Trigili’s recommendations on the entire “Russian Stack”. We have just finished the Pinealon portion and will move into the Dihexa cycle (not Russian) next. Seems to be working for us.

                                For reference, here’s a link to the YT video: https://youtu.be/MyTP0qz8R4s?is=G0ySVCun3SFzBtxK

                                1 Reply Last reply
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                                • S Shaqdiesel

                                  @eleanor Same time but different pins. I do not mix them.

                                  E Online
                                  E Online
                                  Eleanor
                                  wrote last edited by
                                  #16

                                  @Shaqdiesel Thanks diesel!

                                  1 Reply Last reply
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                                  • pep_researcherP pep_researcher

                                    @Stevepep search function is very useful here. 😉

                                    https://community.peptidecritic.com/post/5042

                                    FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                                    E Online
                                    E Online
                                    Eleanor
                                    wrote last edited by
                                    #17

                                    @pep_researcher said:

                                    @Stevepep search function is very useful here. 😉

                                    https://community.peptidecritic.com/post/5042

                                    FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                                    Yeah, that's in peptidedosages too. I'm definitely not going 5mg of Epi but will start with 1 in PM and 1 of Pinealon in AM. I can't imagine a pep that's meant to fix sleep taken in the morning and there's a limit to morning sun I can get; I have to go to work.

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                                    • S Stevepep

                                      Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

                                      gym.ratG Online
                                      gym.ratG Online
                                      gym.rat
                                      wrote last edited by
                                      #18

                                      @Stevepep yep, totally wrong and I see it all over the place. Frankly I'm tired of seeing peptide bros mention this over and over again. ITS WRONG. You don't ever need more than 1mg. In fact I think 1mg was too strong and moved back down to .500mcg. Full "accurate" writeup here with correct dosing for those who are interested: https://peptideprotocols.app/peptides/epitalon

                                      PS - Epitalon works on dose 1 and is in my top 3 of peptides. It also comes attached with the big C word as a theoretical issue, but I honestly don't see the connection and don't give it thought. Just putting that out there in case you have a C word history.

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