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  1. Randy the Rats Research Forum
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Pinealon

Scheduled Pinned Locked Moved Peptide Discussion
41 Posts 11 Posters 5.1k Views
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  • S Offline
    S Offline
    Stevepep
    wrote on last edited by
    #1

    What is the suggested protocol. Just got confused by other posts. @randy you love it please chime in. I am titrating starting at 1mg up to 5 for the last 5 days for 20 days total. Just started

    pep_researcherP 1 Reply Last reply
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    • S Offline
      S Offline
      Shaqdiesel
      wrote on last edited by
      #2

      I did 2.5mgs for 20 days. I think that may be a little high from what I've seen but it did great for me.

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      • M Offline
        M Offline
        matthewwalsh
        wrote on last edited by
        #3

        I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

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        • vpeptidesV Offline
          vpeptidesV Offline
          vpeptides
          wrote on last edited by vpeptides
          #4

          Research on Pinealon used doses from 200mcg with 500mcg suggested as more effective, and patient-specific optimizations up to 3.5mg.
          If taken orally or intranasally it is also usually split to 2-3 doses a day.
          Toxicology studies in pigs showed no organ damage even at 1,000 times the normal dose. Still, high doses can sometimes cause sleepiness, low blood sugar, or mood shifts.
          High doses are around 0.1mg/kg, ~9mg for 200lb.

          attentiion is all you need

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          • M matthewwalsh

            I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

            S Offline
            S Offline
            Shaqdiesel
            wrote on last edited by
            #5

            @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

            vpeptidesV M 2 Replies Last reply
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            • S Shaqdiesel

              @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

              vpeptidesV Offline
              vpeptidesV Offline
              vpeptides
              wrote on last edited by
              #6

              @Shaqdiesel Epitalon is tricky. Next time you may try for an experiment for one or two nights use 0.1-0.2mg. 0.1mg is enough for melatonin production, and over 0.6mg for some may have the opposite effect.

              attentiion is all you need

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              • vpeptidesV vpeptides

                @Shaqdiesel Epitalon is tricky. Next time you may try for an experiment for one or two nights use 0.1-0.2mg. 0.1mg is enough for melatonin production, and over 0.6mg for some may have the opposite effect.

                S Offline
                S Offline
                Shaqdiesel
                wrote on last edited by
                #7

                @vpeptides I did the previous cycle of both before bed. My REM improved a lot along with memory and cognition. I am tempted to change to morning dosing next time per I believe @gym.rat suggestion with morning sunshine.

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                • S Offline
                  S Offline
                  Stevepep
                  wrote on last edited by Stevepep
                  #8

                  Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

                  vpeptidesV 1 Reply Last reply
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                  • S Stevepep

                    Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

                    vpeptidesV Offline
                    vpeptidesV Offline
                    vpeptides
                    wrote on last edited by vpeptides
                    #9

                    @Stevepep The reason is that the original studies, those sites draw the conclusion from, were performed not on epitalon, but on epitalamine - a pineal extract, which contained epitalon at maybe around 5%.
                    For Epitalon studies tested doses 1,000-5,000 times higher than human doses without finding toxic effects. So, they may overshoot but there is no harm.
                    0.1mg is enough for melatonin production, but the high doses may have additional effects too. It is likely that for telomerase production or for broader anti-aging or therapeutic goals you may use up to 5-10mg daily.

                    attentiion is all you need

                    1 Reply Last reply
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                    • S Shaqdiesel

                      @matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

                      M Offline
                      M Offline
                      matthewwalsh
                      wrote on last edited by
                      #10

                      @Shaqdiesel Thank you!

                      1 Reply Last reply
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                      • E Offline
                        E Offline
                        Eleanor
                        wrote on last edited by
                        #11

                        @shaqdiesel Are you pinning Epitalon and Pinealon same time, same of day, or other?

                        Proud to be on a gubmint watch list

                        1 Reply Last reply
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                        • S Offline
                          S Offline
                          Shaqdiesel
                          wrote on last edited by
                          #12

                          @eleanor Same time but different pins. I do not mix them.

                          E 1 Reply Last reply
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                          • M matthewwalsh

                            I tried 2mg for 30 days and didn't do a thing. I'll be trying Epithalon next month and maybe those 2 together at some point.

                            T Offline
                            T Offline
                            TBone
                            wrote on last edited by
                            #13

                            @matthewwalsh I’m just finishing 25 days at 2mg per day. Just prior to that I researched 5mg of Epithalon per day for 20 days. Can’t say I noticed anything different with either. And actually, my sleep has been worse during these cycles. 😕

                            Comfort is the worst addiction - Marcus Aurelius

                            1 Reply Last reply
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                            • S Stevepep

                              What is the suggested protocol. Just got confused by other posts. @randy you love it please chime in. I am titrating starting at 1mg up to 5 for the last 5 days for 20 days total. Just started

                              pep_researcherP Online
                              pep_researcherP Online
                              pep_researcher
                              wrote on last edited by pep_researcher
                              #14

                              @Stevepep search function is very useful here. 😉

                              https://community.peptidecritic.com/post/5042

                              FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                              E 1 Reply Last reply
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                              • judgetooJ Offline
                                judgetooJ Offline
                                judgetoo
                                wrote on last edited by
                                #15

                                We followed Nick Trigili’s recommendations on the entire “Russian Stack”. We have just finished the Pinealon portion and will move into the Dihexa cycle (not Russian) next. Seems to be working for us.

                                For reference, here’s a link to the YT video: https://youtu.be/MyTP0qz8R4s?is=G0ySVCun3SFzBtxK

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                                • S Shaqdiesel

                                  @eleanor Same time but different pins. I do not mix them.

                                  E Offline
                                  E Offline
                                  Eleanor
                                  wrote on last edited by
                                  #16

                                  @Shaqdiesel Thanks diesel!

                                  Proud to be on a gubmint watch list

                                  1 Reply Last reply
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                                  • pep_researcherP pep_researcher

                                    @Stevepep search function is very useful here. 😉

                                    https://community.peptidecritic.com/post/5042

                                    FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                                    E Offline
                                    E Offline
                                    Eleanor
                                    wrote on last edited by
                                    #17

                                    @pep_researcher said:

                                    @Stevepep search function is very useful here. 😉

                                    https://community.peptidecritic.com/post/5042

                                    FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

                                    Yeah, that's in peptidedosages too. I'm definitely not going 5mg of Epi but will start with 1 in PM and 1 of Pinealon in AM. I can't imagine a pep that's meant to fix sleep taken in the morning and there's a limit to morning sun I can get; I have to go to work.

                                    Proud to be on a gubmint watch list

                                    pep_researcherP 1 Reply Last reply
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                                    • vpeptidesV Offline
                                      vpeptidesV Offline
                                      vpeptides
                                      wrote on last edited by vpeptides
                                      #18

                                      @gym.rat said:

                                      the big C word

                                      It is hypothesized as a logical conclusion of Epitalon allegedly increasing telomeres and an observation that some C cells also use telomere elongation as a way to propagate. It was not observed in the studies, afaik. The opposite was observed though.

                                      attentiion is all you need

                                      1 Reply Last reply
                                      0
                                      • vpeptidesV Offline
                                        vpeptidesV Offline
                                        vpeptides
                                        wrote on last edited by
                                        #19

                                        @gym.rat there are in-vitro studies, but in-vivo is yet speculative, especially in humans.

                                        attentiion is all you need

                                        1 Reply Last reply
                                        0
                                        • S Offline
                                          S Offline
                                          Stevepep
                                          wrote on last edited by
                                          #20

                                          @gym.rat first time I have seen this site I will check it out. I am taking 1mg of Pinealon for a couple of days it hasn’t helped sleep at all so I am going to up it and see.

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