Pinealon

[Shaqdiesel]

@matthewwalsh I ran Epitalon at 1mg a day along with the Pinealon. Next time I think I will increase the Epitalon dosage to 2.5 mg a day. I felt like the 2.5 mg of Pinealon was a good dose for me.

[vpeptides]

@Shaqdiesel Epitalon is tricky. Next time you may try for an experiment for one or two nights use 0.1-0.2mg. 0.1mg is enough for melatonin production, and over 0.6mg for some may have the opposite effect.

[Shaqdiesel]

@vpeptides I did the previous cycle of both before bed. My REM improved a lot along with memory and cognition. I am tempted to change to morning dosing next time per I believe @gym.rat suggestion with morning sunshine.

[Stevepep]

Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

[vpeptides]

@Stevepep The reason is that the original studies, those sites draw the conclusion from, were performed not on epitalon, but on epitalamine - a pineal extract, which contained epitalon at maybe around 5%.
For Epitalon studies tested doses 1,000-5,000 times higher than human doses without finding toxic effects. So, they may overshoot but there is no harm.
0.1mg is enough for melatonin production, but the high doses may have additional effects too. It is likely that for telomerase production or for broader anti-aging or therapeutic goals you may use up to 5-10mg daily.

[matthewwalsh]

@Shaqdiesel Thank you!

[Eleanor]

@shaqdiesel Are you pinning Epitalon and Pinealon same time, same of day, or other?

[Shaqdiesel]

@eleanor Same time but different pins. I do not mix them.

[TBone]

@matthewwalsh I’m just finishing 25 days at 2mg per day. Just prior to that I researched 5mg of Epithalon per day for 20 days. Can’t say I noticed anything different with either. And actually, my sleep has been worse during these cycles.

[pep_researcher]

@Stevepep search function is very useful here.

https://community.peptidecritic.com/post/5042

FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

[judgetoo]

We followed Nick Trigili’s recommendations on the entire “Russian Stack”. We have just finished the Pinealon portion and will move into the Dihexa cycle (not Russian) next. Seems to be working for us.

For reference, here’s a link to the YT video: https://youtu.be/MyTP0qz8R4s?is=G0ySVCun3SFzBtxK

[Eleanor]

@Shaqdiesel Thanks diesel!

[Eleanor]

@pep_researcher said:

@Stevepep search function is very useful here.

https://community.peptidecritic.com/post/5042

FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

Yeah, that's in peptidedosages too. I'm definitely not going 5mg of Epi but will start with 1 in PM and 1 of Pinealon in AM. I can't imagine a pep that's meant to fix sleep taken in the morning and there's a limit to morning sun I can get; I have to go to work.

[gym.rat]

@Stevepep yep, totally wrong and I see it all over the place. Frankly I'm tired of seeing peptide bros mention this over and over again. ITS WRONG. You don't ever need more than 1mg. In fact I think 1mg was too strong and moved back down to .500mcg. Full "accurate" writeup here with correct dosing for those who are interested: https://peptideprotocols.app/peptides/epitalon

PS - Epitalon works on dose 1 and is in my top 3 of peptides. It also comes attached with the big C word as a theoretical issue, but I honestly don't see the connection and don't give it thought. Just putting that out there in case you have a C word history.

[vpeptides]

@gym.rat said:

the big C word

It is hypothesized as a logical conclusion of Epitalon allegedly increasing telomeres and an observation that some C cells also use telomere elongation as a way to propagate. It was not observed in the studies afaik.