Pinealon

Stevepep

Epitalon at .2 mg a day. Say what? Everything says 5mg a day for 20 days. https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/

vpeps

@Stevepep The reason is that the original studies, those sites draw the conclusion from, were performed not on epitalon, but on epitalamine - a pineal extract, which contained epitalon at maybe around 5%.
For Epitalon studies tested doses 1,000-5,000 times higher than human doses without finding toxic effects. So, they may overshoot but there is no harm.
0.1mg is enough for melatonin production, but the high doses may have additional effects too. It is likely that for telomerase production or for broader anti-aging or therapeutic goals you may use up to 5-10mg daily.

matthewwalsh

@Shaqdiesel Thank you!

Eleanor

@shaqdiesel Are you pinning Epitalon and Pinealon same time, same of day, or other?

Shaqdiesel

@eleanor Same time but different pins. I do not mix them.

TBone

@matthewwalsh I’m just finishing 25 days at 2mg per day. Just prior to that I researched 5mg of Epithalon per day for 20 days. Can’t say I noticed anything different with either. And actually, my sleep has been worse during these cycles.

pep_researcher

@Stevepep search function is very useful here.

https://community.peptidecritic.com/post/5042

FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

judgetoo

We followed Nick Trigili’s recommendations on the entire “Russian Stack”. We have just finished the Pinealon portion and will move into the Dihexa cycle (not Russian) next. Seems to be working for us.

For reference, here’s a link to the YT video: https://youtu.be/MyTP0qz8R4s?is=G0ySVCun3SFzBtxK

Eleanor

@Shaqdiesel Thanks diesel!

Eleanor

@pep_researcher said:

@Stevepep search function is very useful here.

https://community.peptidecritic.com/post/5042

FWIW some other researchers recommend pinning Pinealon in the morning. Epithalon in the night, Pinealon, Selank, Semax in the morning.

Yeah, that's in peptidedosages too. I'm definitely not going 5mg of Epi but will start with 1 in PM and 1 of Pinealon in AM. I can't imagine a pep that's meant to fix sleep taken in the morning and there's a limit to morning sun I can get; I have to go to work.

vpeps

@gym.rat said:

the big C word

It is hypothesized as a logical conclusion of Epitalon allegedly increasing telomeres and an observation that some C cells also use telomere elongation as a way to propagate. It was not observed in the studies, afaik. The opposite was observed though.

vpeps

@gym.rat there are in-vitro studies, but in-vivo is yet speculative, especially in humans.

Stevepep

@gym.rat first time I have seen this site I will check it out. I am taking 1mg of Pinealon for a couple of days it hasn’t helped sleep at all so I am going to up it and see.

Stevepep

@gym.rat on my Apple Watch

pep_researcher

@Eleanor said:

can't imagine a pep that's meant to fix sleep taken in the morning

I think Pinealon is supposed to fix circadian rhythm. That's why Pinealon, Selank, Semax all are meant to be daytime or morning peps.

Epithalon is supposed to work with melatonin secretion or it promotes it. So taken at night.

Stevepep

@gym.rat funny you say that I just ordered DSIP to try. I am in between cycles so figured I would try something new. Thinking about MotC and NAD+ but have to do some research. Work keeps getting in the way

Stevepep

UPDATE. Just upped to 2mg yesterday am. Best night's sleep ever. According to my apple watch its the most REM and Deep sleep I have ever had. And my wife said no snoring. Some good dreams, too, but I won't get into that.

Shaqdiesel

@Stevepep 2 mgs Of DSIP? Pinealon?

Stevepep

@Shaqdiesel sorry. Pinealon. 2mg as @randy suggested made the difference. I went from one and titrated to 2 over about a week. I didn’t get anything until I went to 2 . Big difference

pep_researcher

@Stevepep I need to recon my vial ASAP now and give it a try.