MOTS-C: Dosing & Blood Pressure Meds
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Looking for some deals on MOTS-C for early Fall use (after I finish current protocols) but have some questions that you fine, experienced folks might be able to answer.
Using link below:
https://peptideinitiative.com/peptides/mots-cIt states a possible effect on blood pressure. Does anyone know if this is a lowering of BP or rise in BP? I have high BP.
Do those who have a plethora of experience with this recommend the starting dose stated?
Does it sting? I like extra BAC for stingers.
Thank you for your kind attention while busy hunting bargains.
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Not sure on the degree of your blood pressure. Notnsure if youre on Ace inhibitors, beta blockers... If youre committing to optimize mitochondria? I would try Co-Q10 and Methylene Blue first. Still considering your blood pressure. You need to lower your inflation first. Foundation first and then you can consider researching with peptides on your own.
"The truth about hypertension" Dr Trevor Backmeyer
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Not sure on the degree of your blood pressure. Notnsure if youre on Ace inhibitors, beta blockers... If youre committing to optimize mitochondria? I would try Co-Q10 and Methylene Blue first. Still considering your blood pressure. You need to lower your inflation first. Foundation first and then you can consider researching with peptides on your own.
"The truth about hypertension" Dr Trevor Backmeyer
Not sure on the degree of your blood pressure. Notnsure if youre on Ace inhibitors, beta blockers... If youre committing to optimize mitochondria? I would try Co-Q10 and Methylene Blue first. Still considering your blood pressure. You need to lower your inflation first. Foundation first and then you can consider researching with peptides on your own.
Thank you for your reply. I think you mean my inflammation, which is well lowered. I'm researching SS-31 before MOTS-C. I really have no interest in Co-Q10 or MBlue. I have a personal program I'm trying to follow. Think I will go with 1/2 doses and monitor BP. Thanks much!
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I have been "diagnosed" with chronic hypertension, I am on week 9 of a 12-week cycle of MOTS-c daily at 1mg (M-F), and I have not noticed any increase of my baseline BP average since starting the MOTS-c. No sting at all for me, I usually pen it in the quad.
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I have been "diagnosed" with chronic hypertension, I am on week 9 of a 12-week cycle of MOTS-c daily at 1mg (M-F), and I have not noticed any increase of my baseline BP average since starting the MOTS-c. No sting at all for me, I usually pen it in the quad.
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I take Amlodipine, Chlorthalidone and dropped Lisinopril and spironolactone while running mots. My blood pressure has stayed the same. I've dropped 78 pounds so that helps also.
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I take Amlodipine, Chlorthalidone and dropped Lisinopril and spironolactone while running mots. My blood pressure has stayed the same. I've dropped 78 pounds so that helps also.
@Hammertime65
Dropping the weight IMO helps more than anything; Dr's can rx overdose, one size fits all. I cut my BP rx's in half. Lisinopril was a real problem with a hacking cough that developed only one month after I started it; sounded like I was barking up a lung. -
Looking for some deals on MOTS-C for early Fall use (after I finish current protocols) but have some questions that you fine, experienced folks might be able to answer.
Using link below:
https://peptideinitiative.com/peptides/mots-cIt states a possible effect on blood pressure. Does anyone know if this is a lowering of BP or rise in BP? I have high BP.
Do those who have a plethora of experience with this recommend the starting dose stated?
Does it sting? I like extra BAC for stingers.
Thank you for your kind attention while busy hunting bargains.
@Eleanor I can tell you right now I would throw that website in the trash. Right off the bat it says to use 5mg dose of MOTS-c which is 100% off the rocker nonsense. Zero credibility and I wouldn't touch any piece of info from there. MOTS-c can send you to the hospital if not careful. Certain people should NOT touch it. It makes me so mad there is such bad info out there. TRASH IT!
I've sent you this link before, but use it. The info here is correct, frequently updated and heavily researched. No stone unturned. https://peptideprotocols.app/peptides/mots-c
For all those in the peanut gallery, if you are taking MOTS-c start small and work your way up. If you have a history of histamine reactions I would not use this pep or proceed with extreme caution. Reactions are more common with this pep than any other I have researched and anaphylactic shock while rare is a possibility. Hives are unfortunately more common than you'd like as well. Don't recon it with BAC water either. All this info is present on the site above. Read before you pin people!!!
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@Eleanor I can tell you right now I would throw that website in the trash. Right off the bat it says to use 5mg dose of MOTS-c which is 100% off the rocker nonsense. Zero credibility and I wouldn't touch any piece of info from there. MOTS-c can send you to the hospital if not careful. Certain people should NOT touch it. It makes me so mad there is such bad info out there. TRASH IT!
I've sent you this link before, but use it. The info here is correct, frequently updated and heavily researched. No stone unturned. https://peptideprotocols.app/peptides/mots-c
For all those in the peanut gallery, if you are taking MOTS-c start small and work your way up. If you have a history of histamine reactions I would not use this pep or proceed with extreme caution. Reactions are more common with this pep than any other I have researched and anaphylactic shock while rare is a possibility. Hives are unfortunately more common than you'd like as well. Don't recon it with BAC water either. All this info is present on the site above. Read before you pin people!!!
-
@Eleanor I can tell you right now I would throw that website in the trash. Right off the bat it says to use 5mg dose of MOTS-c which is 100% off the rocker nonsense. Zero credibility and I wouldn't touch any piece of info from there. MOTS-c can send you to the hospital if not careful. Certain people should NOT touch it. It makes me so mad there is such bad info out there. TRASH IT!
I've sent you this link before, but use it. The info here is correct, frequently updated and heavily researched. No stone unturned. https://peptideprotocols.app/peptides/mots-c
For all those in the peanut gallery, if you are taking MOTS-c start small and work your way up. If you have a history of histamine reactions I would not use this pep or proceed with extreme caution. Reactions are more common with this pep than any other I have researched and anaphylactic shock while rare is a possibility. Hives are unfortunately more common than you'd like as well. Don't recon it with BAC water either. All this info is present on the site above. Read before you pin people!!!
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Found it.
https://peptidetest.com/products/pfizer-hospira-bacteriostatic-sodium-chloride-for-injection-30-ml?_pos=1&_sid=321b006db&_ss=r
Looks like I probably need to wait until cooler weather to order this, per peptide test instructions that it might be more unstable that regular BAC. -
@Eleanor Yes, I get all my Hospira BAC from peptidetest.com. Zero issues and good pricing. Been ordering from them for the last 12 months or so. In fact I just placed an order the other day b/c I'm about to do a cycle of SS-31 myself starting manana.

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Found it.
https://peptidetest.com/products/pfizer-hospira-bacteriostatic-sodium-chloride-for-injection-30-ml?_pos=1&_sid=321b006db&_ss=r
Looks like I probably need to wait until cooler weather to order this, per peptide test instructions that it might be more unstable that regular BAC. -
@gym.rat Thank you! I was actually looking for the link you have posted above. Less is always better as far as I'm concerned. If the starting dose is 1mg, it's 500mcg for me. Thank you very much!
@Eleanor When it comes to MOTS-c, you want to do the repair phase with SS-31 either first or with MOTS-c. They are synergetic. I personally prefer to get 2-3 weeks into an 8 week SS-31 cycle and then add MOTS-c on top M - W - F. I start MOTS-c at 500mcg myself. It's just not a pep I like to screw around with and then slowly titrate up. The goal is to get around or close to 10mg a week once your body adjusts, meaning work up to 3mg a pin. Bacteriostatic saline (0.9% sodium chloride with benzyl alcohol) is a must in my book for MOTS recon. Its isotonic formulation may help reduce injection-site redness, swelling, itching, welts, or hives in sensitive users. For the 45 or so peps I track, MOTS-c has the highest ratio in a side effect profile and the funny thing is those sides (hives or rashes) often come several weeks into the cycle. So far I have not yet come across these side effects with BAC saline, but its still a smaller sample size comparatively.
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@Eleanor When it comes to MOTS-c, you want to do the repair phase with SS-31 either first or with MOTS-c. They are synergetic. I personally prefer to get 2-3 weeks into an 8 week SS-31 cycle and then add MOTS-c on top M - W - F. I start MOTS-c at 500mcg myself. It's just not a pep I like to screw around with and then slowly titrate up. The goal is to get around or close to 10mg a week once your body adjusts, meaning work up to 3mg a pin. Bacteriostatic saline (0.9% sodium chloride with benzyl alcohol) is a must in my book for MOTS recon. Its isotonic formulation may help reduce injection-site redness, swelling, itching, welts, or hives in sensitive users. For the 45 or so peps I track, MOTS-c has the highest ratio in a side effect profile and the funny thing is those sides (hives or rashes) often come several weeks into the cycle. So far I have not yet come across these side effects with BAC saline, but its still a smaller sample size comparatively.
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Not sure on the degree of your blood pressure. Notnsure if youre on Ace inhibitors, beta blockers... If youre committing to optimize mitochondria? I would try Co-Q10 and Methylene Blue first. Still considering your blood pressure. You need to lower your inflation first. Foundation first and then you can consider researching with peptides on your own.
Thank you for your reply. I think you mean my inflammation, which is well lowered. I'm researching SS-31 before MOTS-C. I really have no interest in Co-Q10 or MBlue. I have a personal program I'm trying to follow. Think I will go with 1/2 doses and monitor BP. Thanks much!
@Eleanor Well if youre all in then MOTSC and NAD+ definitely to get the engines running. As soon as you get going in between the cycle throw in SS31. MOTSC signal what to do. NAD+ is the fuel to all mitochondria. SS31 repairs. A car analogy- You need a driver on board to to drive step on the pedal (MOTSC). You need the proper fuel (NAD+). Need a mechanic to repair and patch up the car and engine SS31. The engine cannot be repaired without a driver on low to no fuel? As far as I am concern there isn't anything left to move the needle but mitochondria. Give what you have of mitochondria to run the best they can. Then start repairing. All three do way more then what I described. When you get all three or along the way you will start Mitochondrial biogenesis (make more mitochondria). If you later wants to level up you can clears out dead mitochondria via a cellular process called mitochondria mitophagy by doing a MOTSC, NAD+ and Humanin. Personally I never done it but Humanin is in bucket list of peps. Man there are so many like FOXO4-p53, CRUNCH and of course NAD that clean up dead cells.
Here is a video of this guy who did a cleaning along the way. There are alot of jewels in there. All including Mitochondria optimizations and cleaning with peptides.
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@Eleanor When it comes to MOTS-c, you want to do the repair phase with SS-31 either first or with MOTS-c. They are synergetic. I personally prefer to get 2-3 weeks into an 8 week SS-31 cycle and then add MOTS-c on top M - W - F. I start MOTS-c at 500mcg myself. It's just not a pep I like to screw around with and then slowly titrate up. The goal is to get around or close to 10mg a week once your body adjusts, meaning work up to 3mg a pin. Bacteriostatic saline (0.9% sodium chloride with benzyl alcohol) is a must in my book for MOTS recon. Its isotonic formulation may help reduce injection-site redness, swelling, itching, welts, or hives in sensitive users. For the 45 or so peps I track, MOTS-c has the highest ratio in a side effect profile and the funny thing is those sides (hives or rashes) often come several weeks into the cycle. So far I have not yet come across these side effects with BAC saline, but its still a smaller sample size comparatively.
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@Eleanor Yes, I get all my Hospira BAC from peptidetest.com. Zero issues and good pricing. Been ordering from them for the last 12 months or so. In fact I just placed an order the other day b/c I'm about to do a cycle of SS-31 myself starting manana.

@Eleanor Yes, I get all my Hospira BAC from peptidetest.com. Zero issues and good pricing. Been ordering from them for the last 12 months or so. In fact I just placed an order the other day b/c I'm about to do a cycle of SS-31 myself starting manana.

Ok, well, it's 97 degrees here and up to 90% humidity. Most items delivered during height of heat and I don't get home until 6pm.
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@Eleanor When it comes to MOTS-c, you want to do the repair phase with SS-31 either first or with MOTS-c. They are synergetic. I personally prefer to get 2-3 weeks into an 8 week SS-31 cycle and then add MOTS-c on top M - W - F. I start MOTS-c at 500mcg myself. It's just not a pep I like to screw around with and then slowly titrate up. The goal is to get around or close to 10mg a week once your body adjusts, meaning work up to 3mg a pin. Bacteriostatic saline (0.9% sodium chloride with benzyl alcohol) is a must in my book for MOTS recon. Its isotonic formulation may help reduce injection-site redness, swelling, itching, welts, or hives in sensitive users. For the 45 or so peps I track, MOTS-c has the highest ratio in a side effect profile and the funny thing is those sides (hives or rashes) often come several weeks into the cycle. So far I have not yet come across these side effects with BAC saline, but its still a smaller sample size comparatively.
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