Epitalon / DSIP So many questions
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I ordered DSIP and Epitalon for my hubby's RS and I have searched and searched and I feel comfortable with the dosage for DSIP, but Epitalon appears to be all over the place, depending where you look. I'm seeing to start at .5mg, 5mg and even 10mg per night. If it is 5 or 10 mg per night, that would be an expensive run. I only ordered 2 bottles, because I had the lower dosage (the DSIP dosage) in my head. Silly me.
So, what dosage are you using and are you doing it at night? Most that I have read had been at night, but a few say morning to help reset circadian rhythm?
Should his RS run one and then the other (which one first?), or do people like to run them both at the same time?
I really have searched and it has left me more confused than when I started!
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@Shaqdiesel thank you!
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I ordered DSIP and Epitalon for my hubby's RS and I have searched and searched and I feel comfortable with the dosage for DSIP, but Epitalon appears to be all over the place, depending where you look. I'm seeing to start at .5mg, 5mg and even 10mg per night. If it is 5 or 10 mg per night, that would be an expensive run. I only ordered 2 bottles, because I had the lower dosage (the DSIP dosage) in my head. Silly me.
So, what dosage are you using and are you doing it at night? Most that I have read had been at night, but a few say morning to help reset circadian rhythm?
Should his RS run one and then the other (which one first?), or do people like to run them both at the same time?
I really have searched and it has left me more confused than when I started!
@jackiee First of all, don't worry about its safety, you can use 1 mg or 10 mg or 100 mg of it and be ok, similar to related to it melatonin.
For helping with melatonin production, the effective dosages start with 0.1 mg already, so you can try it at this level for a week and see how it affects you. The more you add the more systems may be affected by it. A lot of things are simply unknown for sure, while there are a lot of claims, there is little to no research. The original inventor's paper gives a range of 0.01mg/kg to 0.1mg/kg, but you can see how arbitrary it is. -
My wife and I recently ran Epitalon for a 20-day cycle at 5mg SubQ roughly 60 minutes before bed. According to my Apple watch, I was getting better quality sleep toward the back half of the cycle. Took a while for it to "kick-in". A month later, I feel like I continue to reap the benefits, but hard to tell. The placebo affect can be strong. We will do another cycle later this year.
We've taken DSIP with mixed results tbh.
It was based on this YT video: https://youtu.be/MyTP0qz8R4s?si=wZqwABvWRUcM0Z4H
We just completed the entire protocol (including Dihexa).
Again, this is just based on our experience and our results.
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@jackiee First of all, don't worry about its safety, you can use 1 mg or 10 mg or 100 mg of it and be ok, similar to related to it melatonin.
For helping with melatonin production, the effective dosages start with 0.1 mg already, so you can try it at this level for a week and see how it affects you. The more you add the more systems may be affected by it. A lot of things are simply unknown for sure, while there are a lot of claims, there is little to no research. The original inventor's paper gives a range of 0.01mg/kg to 0.1mg/kg, but you can see how arbitrary it is.@vpeptides It's for my hubby, not me. I don't think that my sleep scores could get any better! I sleep like it is my job and I'm being paid double time! 94 is a low score for me, lol I take nothing to help me, it just comes naturally, always has. My hubby wants to sleep like me.
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@vpeptides It's for my hubby, not me. I don't think that my sleep scores could get any better! I sleep like it is my job and I'm being paid double time! 94 is a low score for me, lol I take nothing to help me, it just comes naturally, always has. My hubby wants to sleep like me.
@jackiee I tried Epitalon less and more and settled on 2 mg (or 1-2mg). Some say at over 0.6mg intranasally or over 3.5mg subcutaneously it may have an opposite, excitatory effect on some. If you have a quality product, you can safely experiment.
I ran through a few vials over the last 6 months. I did not have problems with sleep and I did not see a lot of effect with sleep to note. (Except the first night when I used 0.1mg I had an especially good sleep for some reason. For me "stress/hrv" factor is bringing the score down, so it was related to it, not sure it was a coincident or not.)
But recently I went through my sleep records and discovered that lately, like in the last 1-2 months, I have about 2 hours of a deep sleep as a rule, while a half year ago the number was more like 1h20m. I don't know it is an effect of Epitalon, but it's something like this that it is researched for.DSIP, I tried that too. To me it seemed the less the better. 0.3mg caused some discomfort feeling in my head, 0.1mg was better. I had a good deep sleep either way or without it too, no difference.
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@jackiee I tried Epitalon less and more and settled on 2 mg (or 1-2mg). Some say at over 0.6mg intranasally or over 3.5mg subcutaneously it may have an opposite, excitatory effect on some. If you have a quality product, you can safely experiment.
I ran through a few vials over the last 6 months. I did not have problems with sleep and I did not see a lot of effect with sleep to note. (Except the first night when I used 0.1mg I had an especially good sleep for some reason. For me "stress/hrv" factor is bringing the score down, so it was related to it, not sure it was a coincident or not.)
But recently I went through my sleep records and discovered that lately, like in the last 1-2 months, I have about 2 hours of a deep sleep as a rule, while a half year ago the number was more like 1h20m. I don't know it is an effect of Epitalon, but it's something like this that it is researched for.DSIP, I tried that too. To me it seemed the less the better. 0.3mg caused some discomfort feeling in my head, 0.1mg was better. I had a good deep sleep either way or without it too, no difference.
@jackiee I tried Epitalon less and more and settled on 2 mg (or 1-2mg). Some say at over 0.6mg intranasally or over 3.5mg subcutaneously it may have an opposite, excitatory effect on some. If you have a quality product, you can safely experiment.
I ran through a few vials over the last 6 months. I did not have problems with sleep and I did not see a lot of effect with sleep to note. (Except the first night when I used 0.1mg I had an especially good sleep for some reason. For me "stress/hrv" factor is bringing the score down, so it was related to it, not sure it was a coincident or not.)
But recently I went through my sleep records and discovered that lately, like in the last 1-2 months, I have about 2 hours of a deep sleep as a rule, while a half year ago the number was more like 1h20m. I don't know it is an effect of Epitalon, but it's something like this that it is researched for.DSIP, I tried that too. To me it seemed the less the better. 0.3mg caused some discomfort feeling in my head, 0.1mg was better. I had a good deep sleep either way or without it too, no difference.
Good to know. Did you run DSIP and epitalon at the same time or one before the other?
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@jackiee I tried Epitalon less and more and settled on 2 mg (or 1-2mg). Some say at over 0.6mg intranasally or over 3.5mg subcutaneously it may have an opposite, excitatory effect on some. If you have a quality product, you can safely experiment.
I ran through a few vials over the last 6 months. I did not have problems with sleep and I did not see a lot of effect with sleep to note. (Except the first night when I used 0.1mg I had an especially good sleep for some reason. For me "stress/hrv" factor is bringing the score down, so it was related to it, not sure it was a coincident or not.)
But recently I went through my sleep records and discovered that lately, like in the last 1-2 months, I have about 2 hours of a deep sleep as a rule, while a half year ago the number was more like 1h20m. I don't know it is an effect of Epitalon, but it's something like this that it is researched for.DSIP, I tried that too. To me it seemed the less the better. 0.3mg caused some discomfort feeling in my head, 0.1mg was better. I had a good deep sleep either way or without it too, no difference.
Good to know. Did you run DSIP and epitalon at the same time or one before the other?
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Opinions vary, IMO if you want better sleep, most people say 1-2MG before bed is perfect. If you are trying to extend your telomeres, many people do 10x10mg or 20x5mg. And some people say the research confused epitalon and epitalimin(or whatever it is) and 10mg is 5-10x too much because epitalon is much stronger.
Either way, it is completely safe, whatever level you research.
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@jackiee do you mean the time of the day or different days? I ran them mostly in separate weeks, first Epitalon, then DSIP.
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@jackiee do you mean the time of the day or different days? I ran them mostly in separate weeks, first Epitalon, then DSIP.
I meant did you run them on different days/weeks/cycles. Like run Epiralon for 20 days then DSIP?
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Dr Kristi Sawivki has a good video about it and she recommends starting at 5-1mg per day, doing 1mg per day.
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Opinions vary, IMO if you want better sleep, most people say 1-2MG before bed is perfect. If you are trying to extend your telomeres, many people do 10x10mg or 20x5mg. And some people say the research confused epitalon and epitalimin(or whatever it is) and 10mg is 5-10x too much because epitalon is much stronger.
Either way, it is completely safe, whatever level you research.
@ResearchCat you are correct epithalamin is the natural, mixed polypeptide extract from bovine pineal glands, whereas epitalon (or epithalon) is a precise, synthetic tetrapeptide isolated and copied from that extract.
Dosing from the studies at 10-5 mg per night were for Epithalamin. In studies Epitalon shows equal or greater biological activity at doses up to 1,000 times lower than those required for crude Epithalamin. Thats where the 500 mcg to 1 mg dosing protocols come from for Epitalon.
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I ordered DSIP and Epitalon for my hubby's RS and I have searched and searched and I feel comfortable with the dosage for DSIP, but Epitalon appears to be all over the place, depending where you look. I'm seeing to start at .5mg, 5mg and even 10mg per night. If it is 5 or 10 mg per night, that would be an expensive run. I only ordered 2 bottles, because I had the lower dosage (the DSIP dosage) in my head. Silly me.
So, what dosage are you using and are you doing it at night? Most that I have read had been at night, but a few say morning to help reset circadian rhythm?
Should his RS run one and then the other (which one first?), or do people like to run them both at the same time?
I really have searched and it has left me more confused than when I started!
@jackiee See my response to reaserch cat about the dosing differences between epitalon and Epithalamin and where the dosing confusion comes from.
I found for me dosing was best at 1mg 30-60 minutes before bed. It was even better stacked with pinealon @ 2 mg first thing in the morning. both for 10 days or you could cut the doses in half for both and do 20 days.
I have done epitalon solo and with Pinealon and I would say the Pinealon, Epitalon combo was far better.
DSIP for me didn't reallly do anything, but my deep sleep is already really good so I didn't notice any benifits, but I wanted to try it anyways.
Hope this helps.
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