Nexaph - Tesamorelin/Ipamorelin purity
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I noticed Aavant's latest Tesa batch also sits at 97% purity, Janoshik COA.
I noticed Aavant's latest Tesa batch also sits at 97% purity, Janoshik COA.
97.98 average purity, I'd call that 98.
I have heard that Tesa, at 44 amino acids, is much more difficult to manufacture than the other GHRH analogs which are 29, and therefor results extra broken proteins which will affect the purity and make hitting 99%+ more difficult.
This leads to a potency issue. Now I certainly wouldn't want something in the 96% range or lower, a 97.98 average purity is probably on par with what everyone's been using this whole time, and those COAs claiming 99%+ were mostly doing less effective testing protocols.
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@icynemby I see. But is that FAQ recently added after the Tesa back to back batches test results or was it always there? Their recent KPV is sitting at sub 99 purity too.
@pep_researcher @icynemby It used to be 99 for GLP products and 98 for the other stuff they reduced the 98 to 97 recently due to Janoshik's latest results. Jano has updated its testing methodology with more recent 100pct reference standards so the results are extremely accurate. My guess is they have been off in the past by a small margin like 1pct. The standards have always been there for the GLP products but testing is improving on all the other peptides. This is my understanding from their telegram and I have asked the question.
Some of the labs have been heavily investing in reference standards I have posted this before. Vanguard has supposedly spent 150k over the last 6 months. Jano double that. The standards allow the lab to pinpoint the peptide and get accurate results without filtering
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Bottom line the Tesa has probably always been 97pct but the testing showed 99. Vanguard and Jano for sure are going to show lower purity results on multiple non glp peptides than other labs
I also ordered the Tesa so I guess I will find out the hard research way
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Bottom line the Tesa has probably always been 97pct but the testing showed 99. Vanguard and Jano for sure are going to show lower purity results on multiple non glp peptides than other labs
I also ordered the Tesa so I guess I will find out the hard research way
@Stevepep I see. I checked Peptidology Tesa as they are one of the very few remaining stateside resellers using Vanguard consistently. Their batches are showing 99% on Tesa.
Skye and Peptide Crafters used Janoshik consistently until a few months ago. But now they too have moved to new kids around the block.
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@stevepep On Krysia's channel dedicated for labs, someone asked about degraded Tesa purity on Janoshik COAs for multiple vendors, whether Jano changed their testing or calibration, and someone from Jano said NO CHANGE.
So had Tesa API or finishing gotten worse??
This is interesting because on Khole Peter responded that they had updated reference samples on several peps a while back. I think Tesa was one of them. Cain though said it was on telegram it’s why they sent the same batch to freedom to compare results
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@stevepep On Krysia's channel dedicated for labs, someone asked about degraded Tesa purity on Janoshik COAs for multiple vendors, whether Jano changed their testing or calibration, and someone from Jano said NO CHANGE.
So had Tesa API or finishing gotten worse??
This is interesting because on Khole Peter responded that they had updated reference samples on several peps a while back. I think Tesa was one of them. Cain though said it was on telegram it’s why they sent the same batch to freedom to compare results
@Stevepep Now I'm very tempted to order a few Tesa samples from different stateside resellers who don't use Janoshik and been showing 99% purity with some other labs to send to Jano to compare. But Tesa vials retail are sold so expensive, that I'm not sure if I want to pursue this "expensive" interest in this economy!
Khole Jano reply is very recent, just 10 days ago.
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@Stevepep Now I'm very tempted to order a few Tesa samples from different stateside resellers who don't use Janoshik and been showing 99% purity with some other labs to send to Jano to compare. But Tesa vials retail are sold so expensive, that I'm not sure if I want to pursue this "expensive" interest in this economy!
Khole Jano reply is very recent, just 10 days ago.
I have Tesa from Instant Peptides who use Kovera and Nextgen who use ILS I can send you if you want to send them for a test. Both of those coa state high 99% purity.
Edit: I even have older Tesa from Nexaph from earlier this year that was tested by Jano and came back high 99% as well. Can send those same ones back to Jano and see if they still come back as 99% or less now.
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I ordered a vial of the same batch of Tesa from Ameano (while it is 50% off total) to try and see it is ok. 97.8% purity from Janoshik lab, but no other problems are detected.
I can offer you one. I have a long-term cooperative manufacturer. Their prices, quality, service and transportation are all excellent. You can check the 99.7 purity test result.
SCAMMER AND SPAM. STAY AWAY FROM THIS PERSONS RECOMMENDATIONS.
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I have Tesa from Instant Peptides who use Kovera and Nextgen who use ILS I can send you if you want to send them for a test. Both of those coa state high 99% purity.
Edit: I even have older Tesa from Nexaph from earlier this year that was tested by Jano and came back high 99% as well. Can send those same ones back to Jano and see if they still come back as 99% or less now.
@denti Thank so much. Are all of these from recent batches though?
Let me do some math. I briefly communicated with Jano customer care and they are very responsive, all replies within a day, given that there is a timezone diff. I communicated with Vanguard too, but they took longer despite being in the same timezone.
If I ever do grey buys and independent testing, I think Jano will be my choice.
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@denti Thank so much. Are all of these from recent batches though?
Let me do some math. I briefly communicated with Jano customer care and they are very responsive, all replies within a day, given that there is a timezone diff. I communicated with Vanguard too, but they took longer despite being in the same timezone.
If I ever do grey buys and independent testing, I think Jano will be my choice.
Nexaph Jano tested is from March 2026 and tested 99.8%
Nextgen ILS tested is from May 2026 and tested 99.5%
Instant Peptides Kovera tested is from August 2026 and tested 99.75%
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Nexaph Jano tested is from March 2026 and tested 99.8%
Nextgen ILS tested is from May 2026 and tested 99.5%
Instant Peptides Kovera tested is from August 2026 and tested 99.75%
@denti We probably want vials finished after Aug 2026 because that's when Tesa started coming out sub 98 purity on multiple grey vendors on Jano COAs. Also unfortunately COA dates from US resellers don't tell when the product was actually finished. If Instant COA is from Aug, Tesa API and lyophilization must have happened a few months before that.
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@denti We probably want vials finished after Aug 2026 because that's when Tesa started coming out sub 98 purity on multiple grey vendors on Jano COAs. Also unfortunately COA dates from US resellers don't tell when the product was actually finished. If Instant COA is from Aug, Tesa API and lyophilization must have happened a few months before that.
@denti We probably want vials finished after Aug 2026 because that's when Tesa started coming out sub 98 purity on multiple grey vendors on Jano COAs. Also unfortunately COA dates from US resellers don't tell when the product was actually finished. If Instant COA is from Aug, Tesa API and lyophilization must have happened a few months before that.
I think it would be interesting to see Jano retest a nexaph batch from earlier this year that got 99.8%. If it comes back at 97 and 98% then we know something has changed on Jano side and not on Nexaph side.
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@Stevepep Now I'm very tempted to order a few Tesa samples from different stateside resellers who don't use Janoshik and been showing 99% purity with some other labs to send to Jano to compare. But Tesa vials retail are sold so expensive, that I'm not sure if I want to pursue this "expensive" interest in this economy!
Khole Jano reply is very recent, just 10 days ago.
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@pep_researcher Someone I know whose rat rhythms with candy may have done this already.
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asked that question regarding the purity, the response was only glp peptides are +/- 99%
Asked whom and who said only GLPs get 99% purity?
That's not true at all. According to test results from Janoshik and other US labs like Vanguard, Trustpointe etc for other non GLP peps.
@pep_researcher Other peptides do test above 99% but the expectation that all peptides are going to be >99% is ridiculous. Look at the purity allowance for peptides in the USP. Oxytocin has a purity spec of greater than 95. That's for pharma grade. Many pharmaceuticals have puritty spec less that 99%
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@stevepep On Krysia's channel dedicated for labs, someone asked about degraded Tesa purity on Janoshik COAs for multiple vendors, whether Jano changed their testing or calibration, and someone from Jano said NO CHANGE.
So had Tesa API or finishing gotten worse??
This is interesting because on Khole Peter responded that they had updated reference samples on several peps a while back. I think Tesa was one of them. Cain though said it was on telegram it’s why they sent the same batch to freedom to compare results
@Stevepep I asked again on K-hole TG channel specifically tagging Peter and he again confirmed that they haven't changed a thing in their testing.
So Tesa manufacturing has gone to dogs overall? This is not a good news for RUO and feeds into the propaganda spread by Eff Dee Aa and Big brothers unfortunately.
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