GLP-1 effects on dopamine
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@ResearchCat in this state of the world I'm not hopeful for the future so I'm good with not extending my lifespan too long. But while I'm here Id like to be as healthy as possible to have a better quality of life.
@ResearchCat in this state of the world I'm not hopeful for the future so I'm good with not extending my lifespan too long. But while I'm here Id like to be as healthy as possible to have a better quality of life.
@beekind That's the idea! Thank you!
@extropian I can't help but be amused when someone tells a 70+ year old to "enjoy the ride", as if I haven't lived to the fullest already. And "live it the best you can". What the heck fire do you think I'm doing?! NO offense meant; I just can't help but chuckle, so thanks for that.
These peptides are a blessing. I now in then still question. Why are these peptides all the sudden out at a time when most are metabolically unhealthy?
Agree with that completely.
Proud to be on a gubmint watch list
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@ResearchCat in this state of the world I'm not hopeful for the future so I'm good with not extending my lifespan too long. But while I'm here Id like to be as healthy as possible to have a better quality of life.
@beekind That's the idea! Thank you!
@extropian I can't help but be amused when someone tells a 70+ year old to "enjoy the ride", as if I haven't lived to the fullest already. And "live it the best you can". What the heck fire do you think I'm doing?! NO offense meant; I just can't help but chuckle, so thanks for that.
These peptides are a blessing. I now in then still question. Why are these peptides all the sudden out at a time when most are metabolically unhealthy?
Agree with that completely.
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@Eleanor I am 55 and still on the roller coaster ride anticipating the next turn. Is wonder completely gone after 70? Ah man, I want off this ride! lol And a red head. Irish?
@EXTROPIAN Slainte Bro!
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@ResearchCat in this state of the world I'm not hopeful for the future so I'm good with not extending my lifespan too long. But while I'm here Id like to be as healthy as possible to have a better quality of life.
@ResearchCat in this state of the world I'm not hopeful for the future so I'm good with not extending my lifespan too long. But while I'm here Id like to be as healthy as possible to have a better quality of life.
The future is going to be great. There will be some bumps and bruises, but if you rip the overlays of politics off, this is a great time to be alive - and the only one you get.
There is a very common human frailty that we indulge that the time we live in is both worse than every other time, and more consequential than every other time. Right now, everyone thinks the 80’s and 90’s were the best. But it’s kind of like everyone who is done with boot camp tells you stories about how great it was.
From a secular perspective, we are in what is called a fourth turning, which is going to be rough no matter what the current batch of idiots is doing. But most of us will be alive for the upswing. (Basically, we are at the ‘weak men make hard times’ period of the cycle. It is an actual thing, as it turns out.)
I was listening to David Sinclair this week and he was talking about how the first person who will live to be 150 is alive today. That’s amazing. Probably won’t be me.
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Tl;DR version of the above.
We can’t choose the times we live in; we can only choose what to do with the time we are given. - Gandalf
Yeah, well, I’m just here for the research, man. - The Dude
If I haven’t liked your post, no offense. I have exceeded my daily allowance.
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Tl;DR version of the above.
We can’t choose the times we live in; we can only choose what to do with the time we are given. - Gandalf
@ResearchCat I'm still ok with not living to 150. Its not promised that it will get better and with technology, AI, data centers, politics, the economy, war, hatred and the lack of humanity in humans, I don't see how any of those things improve without a major catastrophic event. So 75-85 years is ok by me. Life is getting far too expensive. I'm one of those who will probably work until I die because I wasn't given the tools I needed to make good financial decisions early in life so working until 150 sounds AWFUL.
Im still going to enjoy the life I have and do the best to make a better future for my child but I'm not chasing immortality.
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Before Reta, the Beaver enthusiastically did 3 set lifting workouts, swam sets until time to go to work (which is swimming for a beaver).
Reta, slowly decayed to 2 sets, minimal swim sets.
After doing the high dose SS-31 protocol, down to one lifting set per workout and I am in no hurry to get the beaver to the gym on time.
But the beaver feels great. Resting energy is like in its 20s. No more of that viscous friction in the legs when climbing stairs. Dopamine patches help a little. But at what point does one cycle off of Reta to readjust the brain chemistry? Too tell the truth, the beaver is kind of Jonesing for another SS-31 cycle. -
@kenhnsy due to the reduction in neurotransmitters there’s lots of things down river that can take place like vasoconstriction, nitric oxide uncoupling, and things related to antioxidant depletion. Up your antioxidants, polyphenols, and natural vasodilators. Do low dose and work up to not create a bottle neck which will crash your system and make symptoms worse.
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I got an email from the VA recently saying that they are starting to open trials using GLP-1’s for alcohol and drug addiction, which means we will likely see a lot more on this in coming years. They are also starting to investigate psychedelics for TBI and PTSD.
Given the VA’s historical reputation, I see these as good both as a peptide researcher and as a veteran, since these are relatively cutting edge treatments.
It sucks that they only these tests at very limited VAs.
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