CRUSH SS31 gelled - endotoxins?
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I ordered a MTS-31 (aka SS31) from Crush on 2 August, and unfortunately it tuned to gel after adding the BAC water.
Now I am concerned about reconstituting the other vials I bought from them.
The order also contained BPC-157, DSIP, KLOW, and Triple Agonist.Not sure what to do.
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Try adding a little more bac. When I had issues with 10mg ARA gelling with 1ml bac, per Randy’s advice, the solution was to use 1.5ml BW. I now dilute with 2ml to keep math simple and no longer have gel issues.
Follows research backed science, not the gym bro’s.
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I ordered a MTS-31 (aka SS31) from Crush on 2 August, and unfortunately it tuned to gel after adding the BAC water.
Now I am concerned about reconstituting the other vials I bought from them.
The order also contained BPC-157, DSIP, KLOW, and Triple Agonist.Not sure what to do.
-
Try adding a little more bac. When I had issues with 10mg ARA gelling with 1ml bac, per Randy’s advice, the solution was to use 1.5ml BW. I now dilute with 2ml to keep math simple and no longer have gel issues.
@MyB It is a 10mg vial reconstituted with 2mL Lambda Water on the11th of Aug and kept in a zippered black peptide case, and place in a large ziploc bag and stored in the fridge. It is still clear (not cloudy) and runs, but not as fluid as water, and I am not able to draw it.
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UPDATE: I emailed CRUSH and I'm very pleased to say that Audrey from Crush said that she sent me a replacement vial. She said "MTS-31 is known for being susceptible to this issue". I will post a review soon.
MTS-31 is known for being susceptible to this issue
Ummm No.
Yours truly's rat ran a full 10 week protocol with 4mg / ml concentration. No gelling whatsoever. What was the vial size in mg and how many ml BAC was used?
Too concentrated peps tend to aggregate and cause gelling.
Whenever people pin it on vendor vial quality, only a handful of vendors are finishing their own vials stateside. All others are getting finished vials from a handful overseas manufacturers. So if SS-31 is supposed to gel, it will gel across different vendors.
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Try adding a little more bac. When I had issues with 10mg ARA gelling with 1ml bac, per Randy’s advice, the solution was to use 1.5ml BW. I now dilute with 2ml to keep math simple and no longer have gel issues.
Try adding a little more bac. When I had issues with 10mg ARA gelling with 1ml bac, per Randy’s advice, the solution was to use 1.5ml BW. I now dilute with 2ml to keep math simple and no longer have gel issues.
THIS! I didn't read it before and repeated the same thing.
Gelling is less likely pep or vendor issue than BAC quality, concentration of solution, and handling technique issue.
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@MyB It is a 10mg vial reconstituted with 2mL Lambda Water on the11th of Aug and kept in a zippered black peptide case, and place in a large ziploc bag and stored in the fridge. It is still clear (not cloudy) and runs, but not as fluid as water, and I am not able to draw it.
@MyB It is a 10mg vial reconstituted with 2mL Lambda Water on the11th of Aug and kept in a zippered black peptide case, and place in a large ziploc bag and stored in the fridge. It is still clear (not cloudy) and runs, but not as fluid as water, and I am not able to draw it.
That's 5mg/ml, which comes close to gelling boundary. Recommended to keep 4mg/ml or lower concentration.
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@MyB It is a 10mg vial reconstituted with 2mL Lambda Water on the11th of Aug and kept in a zippered black peptide case, and place in a large ziploc bag and stored in the fridge. It is still clear (not cloudy) and runs, but not as fluid as water, and I am not able to draw it.
That's 5mg/ml, which comes close to gelling boundary. Recommended to keep 4mg/ml or lower concentration.
@pep_researcher I was unaware. Is 4mg/ml a good rule of thumb for all peptides or just SS-31? I just reconstituted a vial of SS-31 yesterday with Hospira sodium chloride at 10mg/ml. Would the gelling happen over time or would I know right away?
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MTS-31 is known for being susceptible to this issue
Ummm No.
Yours truly's rat ran a full 10 week protocol with 4mg / ml concentration. No gelling whatsoever. What was the vial size in mg and how many ml BAC was used?
Too concentrated peps tend to aggregate and cause gelling.
Whenever people pin it on vendor vial quality, only a handful of vendors are finishing their own vials stateside. All others are getting finished vials from a handful overseas manufacturers. So if SS-31 is supposed to gel, it will gel across different vendors.
@pep_researcher The vial is 10mg, recontituted with 2mL of Lambda Water. It did not gel immediately, but after 10 days.
All of my reconstituted peptides are kept in a black foam zippered case, placed inside a large ziploc bag, inside the back of the fridge.
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@MyB It is a 10mg vial reconstituted with 2mL Lambda Water on the11th of Aug and kept in a zippered black peptide case, and place in a large ziploc bag and stored in the fridge. It is still clear (not cloudy) and runs, but not as fluid as water, and I am not able to draw it.
That's 5mg/ml, which comes close to gelling boundary. Recommended to keep 4mg/ml or lower concentration.
@pep_researcher ok, thanks. I will reconstitue the new vial with 4mL of BAC.
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@pep_researcher The vial is 10mg, recontituted with 2mL of Lambda Water. It did not gel immediately, but after 10 days.
All of my reconstituted peptides are kept in a black foam zippered case, placed inside a large ziploc bag, inside the back of the fridge.
Lambda Water
This could very well be the culprit, more than the concentration or along with the higher concentration. Try using pH strips to check the pH. If pH is higher than 5.5, it can mess SS-31 or others who can't tolerate more basic pH.
The other thing that doesn't get discussed enough is — handling techniques.
Some researchers follow this strict rule — once a noodle is out of the BAC bottle, no repoking again. Fresh noodle for every fresh poke.
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@pep_researcher I was unaware. Is 4mg/ml a good rule of thumb for all peptides or just SS-31? I just reconstituted a vial of SS-31 yesterday with Hospira sodium chloride at 10mg/ml. Would the gelling happen over time or would I know right away?
Is 4mg/ml a good rule of thumb for all peptides or just SS-31?
No such rule. It really depends on peptide chemistry and also dosing size.
Some researchers use more BAC when dose is smaller than 1mg to reduce margin of error in drawing each dose. If the solution is too concentrated, each unit here and there can sway the dose largely.
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