CAGRI + RETA — New Nature Metabolism Study 🧬
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I wonder if Reta+Eloralintide (Loretta) would have the same 1+1=3 effect as Reta+Cag in this example?
@hunt_ak
I’ve heard of Loretta Jones, but I know her cousin Klorreta Jones a little better — she’s been lovely to me.Jokes aside, I’d be curious about this too. Eloralintide and Cag hit the amylin pathway differently, so I wouldn’t automatically assume Reta + Eloralintide gives the exact same “1+1=3” effect as Reta + Cag. Definitely an interesting combo to watch as more data comes out. Definitely wouldnt be the least surprised if its study in similar settings very soon.
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Cagrilintide was introduced to the test subject prior to nighttime rest. So far, it appears to have been handled pretty well. A little heartburn, but we also had to make some questionable nutritional decisions after our kid had a soccer game 2 hours away... Wendy’s
So I’m not ready to blame Cag for that one.Outside of that, I haven’t experienced anything substantial on the negative side-effect front. Interestingly, while laying down watching TV, I felt a warm/tingling sensation move toward my stomach, almost like the satiety properties were taking effect pretty quickly.
I started extremely low at 0.1333 mg (133 mcg) because I can be fairly sensitive, and if things went sideways I didn’t want my test subject riding it out feeling like crap for a few days
.I’ll track food intake, appetite/satiety, and any nausea or other side effects for the next few days and continue posting the research here. Depending on the response, I’ll adjust from there.
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I wonder if Reta+Eloralintide (Loretta) would have the same 1+1=3 effect as Reta+Cag in this example?
I wonder if Reta+Eloralintide (Loretta) would have the same 1+1=3 effect as Reta+Cag in this example?
i feel like i should get kit of this just for the purpose of having one since it’s a pretty good deal on Tegridy Gb
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@MikeMiranda Wouldnt be a bad call at all my friend. Especially if it continues to prove itself helpful. 1 kit should last a lifetime. Solo Cag protocols ive seen max at 3mg personally think that is insane. Suggestions by fellow researchers has been .25mg (250mcg). I'm sure just like anything in time a bit more will be needed. So far feeling pretty confident in my decision.
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Cagrilintide was introduced to the test subject prior to nighttime rest. So far, it appears to have been handled pretty well. A little heartburn, but we also had to make some questionable nutritional decisions after our kid had a soccer game 2 hours away... Wendy’s
So I’m not ready to blame Cag for that one.Outside of that, I haven’t experienced anything substantial on the negative side-effect front. Interestingly, while laying down watching TV, I felt a warm/tingling sensation move toward my stomach, almost like the satiety properties were taking effect pretty quickly.
I started extremely low at 0.1333 mg (133 mcg) because I can be fairly sensitive, and if things went sideways I didn’t want my test subject riding it out feeling like crap for a few days
.I’ll track food intake, appetite/satiety, and any nausea or other side effects for the next few days and continue posting the research here. Depending on the response, I’ll adjust from there.
@Juliano546 how's the research going?
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@MikeMiranda are you going for the Loretta blend or the elora kits? I want to hoard elora and not sure if I should just get Loretta instead.
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Prolly Loretta
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I wonder how many people have misjudged ratios on these combos (Loretta, Reta/Cagri). The dosing for the Elora is comparable to that of Tirz and Reta. The dosing for Cagri is similar to that of Semaglutide. I can see inadvertently adding .25mg of Elora or 2.5mg of Cagri pretty easily and not seeing the results you expect. The former not having much of an effect, but the latter probably really getting your attention.
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@Juliano546 how's the research going?
@BeeKind So far, Cag is definitely doing its job in the food department.
Previously I was a pretty habitual boredom eater. Now I’ll still wander into the kitchen out of habit, but then... nothing sounds good. I’m hoping over the course of this experiment I can turn that into a more structured habit instead of just relying on the appetite suppression.Side-effect wise, I noticed a temporary uptick in flatulence probably around 12 hours after administration. It didn’t last very long. My personal thought is that my body may simply be reacting to the change and adjusting, but obviously too early to know.
One thing I’m especially interested in tracking: I’ve been walking the line with prediabetes and had started losing sensation in both big toes. Since being on Reta, the right has pretty much returned to normal, while the left has remained stubborn. Since adding Cag, I’m already noticing a little more sensation and less tingling in the left. Way too early to say Cag caused that, but it’s exciting enough that I’ll definitely be watching it.
The other strange sensation I’ve noticed is occasional warmth along the side of my right calf—almost like I’m sitting next to a heater. It comes and goes and hasn’t really bothered me, but it’s another thing I’m tracking.
Weight-wise, I baselined at 232.6 lbs on the 21st, so we’ll see shortly whether there’s been any significant movement.
I also deliberately started with a small dose because if Cag and I weren’t going to be friends, I’d rather not find that out by feeling like absolute shit for several days
. So far though, the experience has been pretty smooth. Thank you for inquiring 
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The gassy thing is absolutely true for me, also. Dose day is Sunday. Gas day is Monday.
I've been looking for testimony about peoples' experiences with adding Cag to Reta. I've been encouraging a friend to try it because she is still having a lot of issues with food noise and habit eating at 6mg/week of Reta. I told her it may make sense to add Cag or Elora at a low dose to see if it's effective before titrating he Reta dose again.
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The gassy thing is absolutely true for me, also. Dose day is Sunday. Gas day is Monday.
I've been looking for testimony about peoples' experiences with adding Cag to Reta. I've been encouraging a friend to try it because she is still having a lot of issues with food noise and habit eating at 6mg/week of Reta. I told her it may make sense to add Cag or Elora at a low dose to see if it's effective before titrating he Reta dose again.
@randallchampion glad im not the only person stinking up this place
. I think she would benefit greatly from it i was at 6mg had a good amount of food noise reduction but adding in the cag has been a new level of satiety. If it comes at the cost of a couple breakages in wind ill happily pay that price . Thanks for the feedback and hope your friend is able to see the benefit. As it can change the response and the price of reta. -
I wonder how many people have misjudged ratios on these combos (Loretta, Reta/Cagri). The dosing for the Elora is comparable to that of Tirz and Reta. The dosing for Cagri is similar to that of Semaglutide. I can see inadvertently adding .25mg of Elora or 2.5mg of Cagri pretty easily and not seeing the results you expect. The former not having much of an effect, but the latter probably really getting your attention.
@randallchampion right this is something to be on the lookout for and ita funny that compounded are already pushing a cagri+reta 5/5 probably gonna get a lot of people sick. Now if they do elora + reta that would definitely seem more practical.
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@randallchampion right this is something to be on the lookout for and ita funny that compounded are already pushing a cagri+reta 5/5 probably gonna get a lot of people sick. Now if they do elora + reta that would definitely seem more practical.
@Juliano546 No mames! I haven't seen that out in the wild. 5mg/5mg Reta/Cag? That's playing with fire.
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@Juliano546 No mames! I haven't seen that out in the wild. 5mg/5mg Reta/Cag? That's playing with fire.
@randallchampion There was a poll in a Discord group with a 5mg/5mg Reta/Cag blend listed, so I can only assume it was a potential new offering from their vendor.
There’s definitely a group of people who believe in microdosing Reta, with some starting around 0.5mg. With a 1:1 blend, even 250mcg of each would be an interesting place conceptually. And Cag has been studied at doses into the multi-milligram range, so there may be more practicality to the ratio than it initially appears.
I personally wouldn’t push Cag anywhere near the upper end, but there may be something to this combination under the surface that we just don’t understand yet. I’m interested to see where the research eventually takes it. If it catches on that is.
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Just started Reta/Cag this week. 1mg/250mcg. So far good results (maybe a little diarrhea nothing more) Question about reconstituting Cag used Bac water as usual. Just read a post stating Cag+bac lasts 3 weeks ish before developing fibrils. Suggested mixing Cag with 75% bac and 25% acetic water. Has anyone seen similar problems with Cag? My pen is only 5 days old so will look for fibrils (?) in cartridge. Anyone with any insight is appreciated
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@randallchampion There was a poll in a Discord group with a 5mg/5mg Reta/Cag blend listed, so I can only assume it was a potential new offering from their vendor.
There’s definitely a group of people who believe in microdosing Reta, with some starting around 0.5mg. With a 1:1 blend, even 250mcg of each would be an interesting place conceptually. And Cag has been studied at doses into the multi-milligram range, so there may be more practicality to the ratio than it initially appears.
I personally wouldn’t push Cag anywhere near the upper end, but there may be something to this combination under the surface that we just don’t understand yet. I’m interested to see where the research eventually takes it. If it catches on that is.
@Juliano546 How's your research going?
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I added Cag to my Reta this week at 100mcg. Cag can pack a wallop when it kicks in, so I'm going SLOOOW with it. I tried once at 250mcg to start and had to quit and wash out. I was sleepy and had brain fog. Serious fatigue.
Figure it's best to start low and be very gradual with it. Find a sweet spot and stop.
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I added Cag to my Reta this week at 100mcg. Cag can pack a wallop when it kicks in, so I'm going SLOOOW with it. I tried once at 250mcg to start and had to quit and wash out. I was sleepy and had brain fog. Serious fatigue.
Figure it's best to start low and be very gradual with it. Find a sweet spot and stop.
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