Eloralintide

vpeps

I have yet to try elora, but I ran 3 weeks of cagri, which is another analog of amylin, 1 mg, and felt absolutely nothing from it. I gave it to try to another person and she felt a major appetite suppression from one dose. So, it might be tricky.

denti

I’ve also been on Enclomiphene to raise my T levels and I wonder if that is causing me to want to eat more. I’ve gained weight in the last 2 months since going off Reta and starting to Enclomiphene. I am ravenous all the time and that’s why I decided to try Elora but still not feeling any of the effects.

Stevepep

@denti is this the Nexaph batch? That is what I am on I just upped to 2mg and for me if I didn’t force myself to eat I wouldn’t. I may go back to 1mg. I am also 170lbs so maybe that’s a consideration in terms of dosing

denti

@Stevepep

Yes Nexaph batch. Purchased a single vial from their sister site AMP to try it out. Literally 3 weeks in I feel no appetite suppression at all. In fact I am always wanting to eat.

I’m at 160lbs. I’m either a non responder to Elora or Enclomiphene or FLGR-242 is making me ravenous all the time.

Randy

@denti im at 2mg and im lucky to get a meal and a half a day. ive done the chengdu and nexaph batches.

ResearchCat

@denti said:

@Stevepep

Yes Nexaph batch. Purchased a single vial from their sister site AMP to try it out. Literally 3 weeks in I feel no appetite suppression at all. In fact I am always wanting to eat.

I’m at 160lbs. I’m either a non responder to Elora or Enclomiphene or FLGR-242 is making me ravenous all the time.

As mentioned many times, it’s important to note changes in behaviors and ‘symptoms’ when changing protocols.

I haven’t started FLGR-242 yet but you are supposed to eat more when using it so adding appetite suppression during what is essentially a build phase might not make sense. I can’t speak to how the enclo affects your appetite specifically; I have not experienced a notable change in appetite, except to note that Ihave increased my tirz to 6/7mg/week to slowly lose a few more pounds.

If you don’t journal, I’d recommend starting one, noting weight, appetite, emotions, research protocols and changes, and depending on how OCD you are, bowel movements and other fun stuff.

denti

I am going to stop Enclo and FLGR-242 this weekend and increase Elora to 3mg next week to see if it finally kicks in for me.

Randy

@denti oh yeah enclo always made me a bottomless pit.

DocCherie

@denti that's disappointing. It is/was on my list to try.

morethanalabel

I just started with adding 1mg a week to my 5mg of Reta. Reta was just not taking care of my food noise. I seem to have less but it has only been a week.

afkar7

@morethanalabel said:

I just started with adding 1mg a week to my 5mg of Reta. Reta was just not taking care of my food noise. I seem to have less but it has only been a week.

I'm doing the same the past three weeks. The 1mg of elora has helped me with the food noise.

mikebricker

@afkar7 I plan to start that Monday. 1mg Elora with 1.6mg Reta. I’m at my goal weight so I’m dropping the 5mg Tirz but as we all know, Reta doesn’t do jack for appetite or food noise, hence the Elora. Plus I like that name “Loretta” stack….
Note: I lost 30 pounds 202-172 with 5mg Tirz and 1.6mg Reta.

ogsteve

So where are we at on how to test this stuff? Do labs need to test for the methlyene thioacetyl bridge or is there another way or is it assumed if it hits other points?

Randy

@ogsteve no labs need to do the dilution calculations right.

https://peptidecritic.com/lab-report/we-bought-eloralintide-then-lab-results-stopped-adding

mikebricker

@ogsteve Bridge not required. Just match against the reference standard LC/MS. Even the head bubba at Janoshik agrees.

afkar7

@mikebricker said:

@afkar7 I plan to start that Monday. 1mg Elora with 1.6mg Reta. I’m at my goal weight so I’m dropping the 5mg Tirz but as we all know, Reta doesn’t do jack for appetite or food noise, hence the Elora. Plus I like that name “Loretta” stack….
Note: I lost 30 pounds 202-172 with 5mg Tirz and 1.6mg Reta.

As much as I have liked Reta I have to agree with that. Didn't start that way but has gone that route since I started so It's why I added Elora. Wanted to see if it helped with the noise and appetite and it has. Ive been at 5mg now for a while as a maintenance level. I have gone from 178 to 150. I know most people will say that's stupid but I was not happy at the 178 weight. I'm only 5'8" and have always been a small/slim guy. I love where I am now. I hit the gym five days a week so it's not like I'm all skin and bones IMHO.

Not a great before and after my change over six months.

mhf

My research is currently Reta 8mg weekly, and Tesa/Ipa blend 2.6/0.6 nightly. Wanting to add Elora to experiment. I am thinking I should drop Reta to 4mg weekly and Elora at 1mg weekly. Does this sound reasonable?

Also, my biggest issue is itchiness and small welts, Reta almost always and the Tesa/Ipa sometimes. The welts lasts less than a few hours, the itchiness a few days. Does anyone have similar experiences and have any thoughts, and does Elora generally generate the same reaction?

TBone

@afkar7 Much respect!

mikebricker

@mhf It takes a while to get to your steady state body burden with Elora.
With Reta, about 4 weeks and your average body burden is about 125% of your single weekly dose. But with Elora and two week half life, the average body burden is about 300% of your weekly dose.
So if you’re on 1.5mg/wk Reta you’re at about 2mg avg BB anfter 4 weeks.
And with 1.5mg/wk Elora you’re at about 4.5mg avg BB after 8 weeks.
With Elora we need more patience….

JtCjEfF

@mikebricker Ive heard the general rule of thumb for drugs is "5 half-lives". So Elora is ~14 days, that means were looking at 70 days before fully titrated. Thats my understanding anyways.