MOTS - C who shouldn’t take it? Side effects / potential dangers?
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Hey guys, been recently learning about MOTS-C, and still am. I recently saw the dosing protocol posted on the form, but wanted to see if there were any recommendations from anyone regarding dosing and cycle, as well as any side effects or possible dangers that could come up? Any specific factor or disease that one might have that would not be recommended to take MOTS-C with?
Regarding stacking with GHK CU and Reta , does it impact any of those, or will MOTS-C be impacted by either one? Or any other things you guys might know about stacking these together? Thank you guys in advance for your help!!
@Peptide-geek
Start Low and Go Slow -
@Randy it’s the weirdest peptide there is no in between it either works great or you have a nasty reaction.
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5mgs 3x a week for me but I am always concerned that the allergic reaction could kick in at any moment. Definitely a start really low and go slow until you are sure your body does okay with it.
Edit: Not a bad idea to have an EPI pen or 2 handy in case of an emergency with this pepper.
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Have you tried it on your rats?
Yes it worked fine for me but it’s different for everyone. I just cycled off for a month and liked it a lot. I titrated up to 6mg 3x per week for 6 weeks. I have seen people have no reaction when they start and wake up with red blotches all over due to a histamine reaction. It builds up in your body over time. I was getting an itchy red area but then I switched to Hospira NACL Bac and it stopped. That’s just me though. We all react differently. So go slow
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Have you tried it on your rats?
Yes it worked fine for me but it’s different for everyone. I just cycled off for a month and liked it a lot. I titrated up to 6mg 3x per week for 6 weeks. I have seen people have no reaction when they start and wake up with red blotches all over due to a histamine reaction. It builds up in your body over time. I was getting an itchy red area but then I switched to Hospira NACL Bac and it stopped. That’s just me though. We all react differently. So go slow
@Stevepep I'm going to try the NaCl BAC on my next vial just to see how it is. I don't get much for ISRs but a small lump and itch with SS-31, MOTs and 5Amino.
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Have you tried it on your rats?
Yes it worked fine for me but it’s different for everyone. I just cycled off for a month and liked it a lot. I titrated up to 6mg 3x per week for 6 weeks. I have seen people have no reaction when they start and wake up with red blotches all over due to a histamine reaction. It builds up in your body over time. I was getting an itchy red area but then I switched to Hospira NACL Bac and it stopped. That’s just me though. We all react differently. So go slow
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5mgs 3x a week for me but I am always concerned that the allergic reaction could kick in at any moment. Definitely a start really low and go slow until you are sure your body does okay with it.
Edit: Not a bad idea to have an EPI pen or 2 handy in case of an emergency with this pepper.
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I like this purely for emergency backup and peace of mind:
https://goodlifesupplies.com/product/in-case-of-emergency-kit/ -
Edit: Not a bad idea to have an EPI pen or 2 handy in case of an emergency with this pepper.
Where to get it without prescription?
@mmp Just tell your doc you ate something that gave you a scare. Or a bee stung you and you swelled up a lot and want to have a couple just in case.
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I just finished a MotsC cycle and didn’t really notice anything at 10mg MWF. Doesn’t mean it didn’t ng work, but I certainly didn’t feel it. Just switched over to ATX-304 as many believe it to be superior to motsc and is one less poke due to it being in pill form. We shall see!
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@Stevepep I'm going to try the NaCl BAC on my next vial just to see how it is. I don't get much for ISRs but a small lump and itch with SS-31, MOTs and 5Amino.
@Shaqdiesel I am not sure if it is ok for 5 Amino. It is for SS31 and MOTSC and I use it for buffered NAD as well
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I’ve seen one article cautioning it’s use for anyone with MTHFR and/or issue with their methylation cycle.
I’ve seen one article cautioning it’s use for anyone with MTHFR and/or issue with their methylation cycle.
I have MTHFR and take 1mg/d with NAD+buff. I do take extra B with it and only problem is it keeps me from sleeping well. After this vial is done, the remainder goes into the freezer.
Mixes very well with NaCl BAC.
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@Shaqdiesel I am not sure if it is ok for 5 Amino. It is for SS31 and MOTSC and I use it for buffered NAD as well
@Stevepep My HVY 5Amino came premixed so I am only using on the MOTS and SS. I was just mentioning I do get a minor ISR with the 5Amino.
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@Stevepep My HVY 5Amino came premixed so I am only using on the MOTS and SS. I was just mentioning I do get a minor ISR with the 5Amino.
@Shaqdiesel gotcha I haven't tried 5 amino
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got two freaking kits because of the rave reviews about mitochondrial research and all. felt nothing different.Rat had one serious ISR that lasted a week when it tried on the low fatty portion of thigh which went IM and then it was horrible. Had to take some Benadryl to alleviate the intense itch.
Rat switched back to fatty site and now just been depleting the stock to get done with it.
Same experience with SS-31 and NAD precursors. Money down the drain for experiments with no meaningful outcomes.
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@Randy it’s the weirdest peptide there is no in between it either works great or you have a nasty reaction.
@Stevepep Third category of
who just feel meh and feel like money, BAC, noodles, wipes down the drain because of no meaningful research outcome. -
FWIW, the bump and itch can alleviate a lot if research site has enough pinch of fat and you apply cold pack immediately after pinning MOTS-C.
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Took it for a few months and took a 2 week break for a trip. Even with maybe 25 percent left of a vial im probably not restarting just based on the fear of stopping and restarting. The weight loss from it wasnt worth the gamble. It wasn't significant for me. Could do slu915, atx304, aicar, or even bam15 and not have to worry.
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