Tesamorelin Research Dosing Protocol
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Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.
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I left a review for crush when they weren’t listed because I understood it to be open. Think they get added based on reviews?
@WisGal64 oh really? I deleted my post because it didn’t have a tag for the vendor. But I’ll re-upload it
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Thoughts on doing a Tesa/Ipa protocol? I was watching a video yesterday talking about doing that with a morning injection schedule to take advantage of overnight fasting and then not eating for a few hours. This would work well for intermittent fasting regimens, might help with sleep, and is supposed to be better for shredding.
I just finished a CJC/IPA cycle and between the challenge of fasting (I don’t get home til after 9 a lot) and not sleeping great on it, I’m thinking about alternatives down the road. CJC/IPA definitely works for me but might not be ideal, and sermorelin is quite subtle.
@ResearchCat I was doing my second vial of chc/ipa and was really loving the sleep and recovery. I heard a video of adding tesamoreline so added .5 mg then stopped the cjc and was doing 1 mg of Tesa at night for a week. I had one more dose left but I tossed it.
My back got sore, my joints were stiff and it felt like tesa was working completely against my recovery stack.
Last night, my sleep wasn’t as good and needed to take a KPV to help with all that inflammation. I also ate some yogurt which hunger seems to be working against the body composition goals. Im going to the hotsprings, taking the weekend off and may restart my cjc/ipa Monday night. I also did a BPC 157 this morning with another KPV, which is helping. Tesa is NOT for me… -
Well, all this just kinda blows me out of the water. I need to get rid of a lot of visceral fat; I mean A LOT. The DEXA was horrible! I'm not that overweight, but the Dr. said, and I concur, it's been there a long time and I was raised on a Southern diet. I'm currently taking Tirzep once/wk on Friday night; nothing to eat since lunch, except very light snack later so stomach's not growling. NAD+ M,W & Sat, mornings upon waking, approx 10 hour fast. I have trouble sleeping and get up at 4:30, so not sure where to fit in Tesa. Question for all, but esp. for @randy Do Tesa and NAD+ work well together? I can cut back on the NAD, but not the Tirzep. I could also stay on lower does of Tesa for longer. What do y'all think?
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M.D.? Someone mentioned somewhere on this blog that all the influencers out there are DC's or anything other than MD's. Maybe this one is MD? Got to go to work right now but will look up licensing this weekend.
https://youtu.be/Ky5Hodz3-9A?si=P0iLJhekK0GujTSo -
What is the NAD+ for? I don’t know your history or goals, but almost think that MOTS-C might be more effective if you are trying to burn fat, especially if you are exercising.
I see no issues researching NAD+/MOTS-C with a GHRH. You can research Tesa/Ipa/CJC first thing in the morning fasted or an hour before bed after fasting 2-3 hours.
I am not a doctor, or your doctor, but I like to have a specific goal and purpose for whatever peptides I am researching, even if I am researching several at the same time. ;). At the moment, I am much more bullish on MOTS-C than on NAD+ as part of an ongoing maintenance stack.
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What is the NAD+ for? I don’t know your history or goals, but almost think that MOTS-C might be more effective if you are trying to burn fat, especially if you are exercising.
I see no issues researching NAD+/MOTS-C with a GHRH. You can research Tesa/Ipa/CJC first thing in the morning fasted or an hour before bed after fasting 2-3 hours.
I am not a doctor, or your doctor, but I like to have a specific goal and purpose for whatever peptides I am researching, even if I am researching several at the same time. ;). At the moment, I am much more bullish on MOTS-C than on NAD+ as part of an ongoing maintenance stack.
@ResearchCat NAD+ really kept me on my feet when I first started Tirzep; I still have 4 vials of it and am going to use it. Depending on how I'm feeling when I've used it up will determine if I buy more. When something works, I try not to change it. Problem is that I get relatively wired on it; I have a high stress job, and have trouble sleeping. I've recently reduced the dose, so will see if I can find a sweet spot. Thanks for the ideas! I imagine I will try a number of them before all's said and done.
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If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.
I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.
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Also, I totally understand the high stress job thing.

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If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.
I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.
@ResearchCat I understand your concern. I'm eating plenty, trust me! I have other considerations, ex: I had an advanced case of Lyme Disease and 3 co-infections that took about 13 years (on & off) to get under control. Somewhere during that process, I lost 5.5' of bowel; to say I have absorption problems is an understatement, plus the MTHFR. There's a long laundry list my 70 yrs has collected. The energy loss started from the very beginning, but love the weight loss results. I think I'm probably taking NAD too many times per week, or too much. I cannot toss peps to the side, unless they're truly making me ill; my budget is so limited. Experimenting right now to find a good mix.
I definitely want to add Tesa and will just have to deal with more experimenting.