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Tesamorelin Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
tesamorelinresearching
120 Posts 42 Posters 14.4k Views 4 Watching
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  • pep_researcherP pep_researcher

    If Tesa 600mcg has improved deep and REM sleep and giving some fluid retention on feet, should 🐀 assume it's working on reducing fat too?

    Or should 🐀 go to 1mg and beyond? Rat started just about 3 weeks ago and gradually upped from 400mcg to 600mcg. Rat is not very overweight, but rat's lipids aren't optimal hinting liver and visceral fat (Skinny Fat kindaa situation).

    EXTROPIANE Offline
    EXTROPIANE Offline
    EXTROPIAN
    wrote last edited by EXTROPIAN
    #87

    @pep_researcher I can not get passed 1mg without feeling something. I got writers lock ,now some mid back stiffness and some dysesthesia. I had to dial it back to 600mcgs. Pros it has suppressed my appetite a lil more on top of reta. I am trimming slowly. This one I have to watch for though. I don't mind, it gives me an extra week with a 10mg vial. I am about finding the lowest most effective dose and patients. If the symptoms persist I'll dialed it down even more.

    2M

    1 Reply Last reply
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    • C Offline
      C Offline
      Commander
      wrote last edited by
      #88

      I have a good friend that was on 2mg a night. She started getting tingling in her hands. She back it down to 1.5mg and it was better, but still had some tingling. She is going to back it down to 1mg and see if that gets rid of the side effects.
      But the funny thing is she was on 2mg for months with no problems. She is pissed because she gets great sleep with Tesa/IPA.

      Please excuse my typos. Small Phone & Bad Eyes

      M 1 Reply Last reply
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      • C Commander

        I have a good friend that was on 2mg a night. She started getting tingling in her hands. She back it down to 1.5mg and it was better, but still had some tingling. She is going to back it down to 1mg and see if that gets rid of the side effects.
        But the funny thing is she was on 2mg for months with no problems. She is pissed because she gets great sleep with Tesa/IPA.

        M Offline
        M Offline
        MikeMiranda
        wrote last edited by
        #89

        @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

        C 1 Reply Last reply
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        • M MikeMiranda

          @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

          C Offline
          C Offline
          Commander
          wrote last edited by
          #90

          @MikeMiranda said:

          @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

          Didn't know there was different ones. So what one is the one that we get when we buy it?

          Please excuse my typos. Small Phone & Bad Eyes

          M S 2 Replies Last reply
          0
          • C Commander

            @MikeMiranda said:

            @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

            Didn't know there was different ones. So what one is the one that we get when we buy it?

            M Offline
            M Offline
            MikeMiranda
            wrote last edited by
            #91

            @Commander said:

            @MikeMiranda said:

            @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

            Didn't know there was different ones. So what one is the one that we get when we buy it?

            I just learned it the other day when I was doin some reading from the NIH studies

            1 Reply Last reply
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            • quicksilver80Q Offline
              quicksilver80Q Offline
              quicksilver80
              wrote last edited by
              #92

              Ts at 2mg daily. Probably 3 vials in? Energy, strength, feels great. Taken fasted at night. Sleep like rs is dead. Zero negative sides. Maybe a itchy s.i. Thats about it. Id bet randy would know better but since its asking the body to produce it naturally i feel like the risks are only burning out the receptors? Ts feels better than he did in his teens.

              1 Reply Last reply
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              • M Offline
                M Offline
                MikeMiranda
                wrote last edited by
                #93

                Testing was 26 weeks no cycling off, Testing didn't even mention fasting

                N 1 Reply Last reply
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                • Mr SmurfM Offline
                  Mr SmurfM Offline
                  Mr Smurf
                  wrote last edited by
                  #94

                  Screenshot_20260825_113905.jpg
                  This is an inbody scan, so take it or leave it i suppose. But the visceral fat reading.. id say tesa works, been running it since April

                  Mydogdaryl423M 1 Reply Last reply
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                  • Mr SmurfM Mr Smurf

                    Screenshot_20260825_113905.jpg
                    This is an inbody scan, so take it or leave it i suppose. But the visceral fat reading.. id say tesa works, been running it since April

                    Mydogdaryl423M Offline
                    Mydogdaryl423M Offline
                    Mydogdaryl423
                    wrote last edited by
                    #95

                    @Mr-Smurf said:

                    Screenshot_20260825_113905.jpg
                    This is an inbody scan, so take it or leave it i suppose. But the visceral fat reading.. id say tesa works, been running it since April

                    Do you have your data from April? What did your numbers look like previously?

                    Mr SmurfM 1 Reply Last reply
                    0
                    • Mydogdaryl423M Mydogdaryl423

                      @Mr-Smurf said:

                      Screenshot_20260825_113905.jpg
                      This is an inbody scan, so take it or leave it i suppose. But the visceral fat reading.. id say tesa works, been running it since April

                      Do you have your data from April? What did your numbers look like previously?

                      Mr SmurfM Offline
                      Mr SmurfM Offline
                      Mr Smurf
                      wrote last edited by
                      #96

                      @Mydogdaryl423 sadly I dont. This all happened in a way I can only really describe as winging it. April i was probably about 30-35 pounds over what I am now, and down 85 overall. I genuinely wish I had the foresight at the time to get my baseline numbers.

                      1 Reply Last reply
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                      • Mydogdaryl423M Offline
                        Mydogdaryl423M Offline
                        Mydogdaryl423
                        wrote last edited by
                        #97

                        Regardless, congrats on your progress. Huge accomplishment.

                        1 Reply Last reply
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                        • EXTROPIANE Offline
                          EXTROPIANE Offline
                          EXTROPIAN
                          wrote last edited by
                          #98

                          I am shelving the tesa again. Still not for me.

                          2M

                          1 Reply Last reply
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                          • D Offline
                            D Offline
                            DarkStar
                            wrote last edited by
                            #99

                            My pet's current research stack is KLOW daily, Tesa/Ipa (500 mcg of the Tesa, a pretty light dose) nearly daily (depends on when I'm fasted for long enough for it to be effective), Semax/Selank 3-4 days/week, and Reta weekly.

                            My pet was on Tirz for a few months (got up to 7.5 mg/week) before it decided to wash out and start with Reta. He was also on CJC-1295 No DAC/Tesa/Ipa for a couple months before switching to the Tesa/Ipa only combo.

                            I switched him to just the Tesa/Ipa combo without the CJC-1295 primarily because of the cost. I prefer pre-mixed compounds because dealing with 5-8 sticks a day would be too time consuming for me to maintain, generate a sh*tload of pen caps, and require so much time reconstituting and transferring to pens. I couldn't find a decent price for that compound so I switched him to just the Tesa/Ipa.

                            First thing I noticed was that he didn't flush as bad without the CJC-1295 and that his sleep wasn't as affected. The CJC-1295 must have been the culprit for his restless nights. Second thing I noticed is that there appears to be no real difference in his results. Mid-section fat has been coming off pretty consistently and muscle loss has been minimal considering that his idea of a workout happens during the course of his work week and not in a gym. I'm very happy with his results.

                            The Semax/Selank combo is very noticeable. He feels sharper and tougher to rattle on the days he takes it. His job is fast paced and has a lot of moving parts, so improved brain function is an incredible aid.

                            Regarding the switch from Tirz to Reta, at first he thought the Reta was less effective because it wasn't as noticeable during the first couple weeks at 2 mg/week. He titrated up to 4 mg/week starting with week 3 and still doesn't notice the effect as much as when he first started Tirz. Food noise is gone, but he actually has less discomfort from eating than he experienced with Tirz. Most subjects note more side effects from Reta, but this one has not. It's quite perfect, actually. He doesn't have to force himself to eat but is still very mindful of his diet choices and portions.

                            Anyway, this stack has worked very well and I don't plan to change it on him anytime soon except to maybe up the Tesa/Ipa dosage. Down from 275# at his highest to 240# currently after about 4 months with no noticeable muscle loss. He isn't approaching it as a race, he's trying to keep the loss consistent and manageable to mitigate side effects like excess skin and muscle loss.

                            B 1 Reply Last reply
                            1
                            • C Offline
                              C Offline
                              Commander
                              wrote last edited by
                              #100

                              I don’t know why everyone here gives these expensive peptides to all these pets… I take all of them myself and don’t share with any pets, they are way too expensive.

                              Please excuse my typos. Small Phone & Bad Eyes

                              vpepsV D 2 Replies Last reply
                              6
                              • C Commander

                                I don’t know why everyone here gives these expensive peptides to all these pets… I take all of them myself and don’t share with any pets, they are way too expensive.

                                vpepsV Offline
                                vpepsV Offline
                                vpeps
                                wrote last edited by vpeps
                                #101

                                @Commander pets are not cheap these days either. I paid for my dog more than its weight worth in silver, even now full grown. But recently I gave her some pet peptides and she pooped out like a third of its weight. Life is not simple.

                                attentiion is all you need

                                1 Reply Last reply
                                0
                                • C Offline
                                  C Offline
                                  Commander
                                  wrote last edited by
                                  #102

                                  Unfortunately… Everything is expensive these days!!!I am just a poor man living in a rich mans world.

                                  Please excuse my typos. Small Phone & Bad Eyes

                                  1 Reply Last reply
                                  2
                                  • EXTROPIANE Offline
                                    EXTROPIANE Offline
                                    EXTROPIAN
                                    wrote last edited by
                                    #103

                                    quote-and-how-am-i-to-face-the-odds-of-man-s-bedevilment-and-god-s-i-a-stranger-and-afraid-a-e-housman-89-97-91.jpg

                                    2M

                                    1 Reply Last reply
                                    0
                                    • D DarkStar

                                      My pet's current research stack is KLOW daily, Tesa/Ipa (500 mcg of the Tesa, a pretty light dose) nearly daily (depends on when I'm fasted for long enough for it to be effective), Semax/Selank 3-4 days/week, and Reta weekly.

                                      My pet was on Tirz for a few months (got up to 7.5 mg/week) before it decided to wash out and start with Reta. He was also on CJC-1295 No DAC/Tesa/Ipa for a couple months before switching to the Tesa/Ipa only combo.

                                      I switched him to just the Tesa/Ipa combo without the CJC-1295 primarily because of the cost. I prefer pre-mixed compounds because dealing with 5-8 sticks a day would be too time consuming for me to maintain, generate a sh*tload of pen caps, and require so much time reconstituting and transferring to pens. I couldn't find a decent price for that compound so I switched him to just the Tesa/Ipa.

                                      First thing I noticed was that he didn't flush as bad without the CJC-1295 and that his sleep wasn't as affected. The CJC-1295 must have been the culprit for his restless nights. Second thing I noticed is that there appears to be no real difference in his results. Mid-section fat has been coming off pretty consistently and muscle loss has been minimal considering that his idea of a workout happens during the course of his work week and not in a gym. I'm very happy with his results.

                                      The Semax/Selank combo is very noticeable. He feels sharper and tougher to rattle on the days he takes it. His job is fast paced and has a lot of moving parts, so improved brain function is an incredible aid.

                                      Regarding the switch from Tirz to Reta, at first he thought the Reta was less effective because it wasn't as noticeable during the first couple weeks at 2 mg/week. He titrated up to 4 mg/week starting with week 3 and still doesn't notice the effect as much as when he first started Tirz. Food noise is gone, but he actually has less discomfort from eating than he experienced with Tirz. Most subjects note more side effects from Reta, but this one has not. It's quite perfect, actually. He doesn't have to force himself to eat but is still very mindful of his diet choices and portions.

                                      Anyway, this stack has worked very well and I don't plan to change it on him anytime soon except to maybe up the Tesa/Ipa dosage. Down from 275# at his highest to 240# currently after about 4 months with no noticeable muscle loss. He isn't approaching it as a race, he's trying to keep the loss consistent and manageable to mitigate side effects like excess skin and muscle loss.

                                      B Offline
                                      B Offline
                                      blueskies27
                                      wrote last edited by blueskies27
                                      #104

                                      @randallchampion Does the tesa/ipa combo need to be kept in the fridge? I know tesa alone can be kept in a cool, dark, room temp place but curious about the combo. Also, ipa is known to help improve sleep. Was your rat running this in the am or pm? Thanks

                                      pep_researcherP D 2 Replies Last reply
                                      0
                                      • D Offline
                                        D Offline
                                        derekg1
                                        wrote last edited by
                                        #105

                                        I believe it is best to keep all reconstituted peptides in a fridge.

                                        1 Reply Last reply
                                        3
                                        • B blueskies27

                                          @randallchampion Does the tesa/ipa combo need to be kept in the fridge? I know tesa alone can be kept in a cool, dark, room temp place but curious about the combo. Also, ipa is known to help improve sleep. Was your rat running this in the am or pm? Thanks

                                          pep_researcherP Offline
                                          pep_researcherP Offline
                                          pep_researcher
                                          wrote last edited by
                                          #106

                                          @blueskies27 Everything that has BAC water in it inside the fridge unless you are researching something within a day or recon.

                                          1 Reply Last reply
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