Klotho / FLGR242 (albumin-bound new tech)
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Yeah someone's needs to put a foot in the grey markets ass so normal mortals can get kits. Been thinking the synergy between growth and this would be interesting once you get past the water retention. Seeing how epicatechin works in the mean time.
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@PeptidePete Thanks for the update! You are about 2 months ahead in your research compared to me. Not on Klotho. Never used gear but, man, things are happening! First got veiny and leaned out -also 31 waist now! Then felt like changes stalled a bit. Went off Reta and bam- muscles that haven't grown in decades are adding mass. Good to hear the echo is clean. Curious if you plan on taking a break at some point, as recommended on the website cheatsheet? Hate to stop but trying to figure out if I should do this sooner (and shorten the 'off' period) or keep going for now and break later (but make it longer. Plus feel free to add any other insights or words of wisdom!
@PeptidePete Thanks for the update! You are about 2 months ahead in your research compared to me. Not on Klotho. Never used gear but, man, things are happening! First got veiny and leaned out -also 31 waist now! Then felt like changes stalled a bit. Went off Reta and bam- muscles that haven't grown in decades are adding mass. Good to hear the echo is clean. Curious if you plan on taking a break at some point, as recommended on the website cheatsheet? Hate to stop but trying to figure out if I should do this sooner (and shorten the 'off' period) or keep going for now and break later (but make it longer. Plus feel free to add any other insights or words of wisdom!
Great to read your experience. Parallels mine. Their protocols can be...stupid. I have zero intention to cycle or stop FLGR242, why would I. Look at the myostatin genetic knockouts as reference.
Insight- if someone is on reta for example, you'll lose fat but difficult to put on muscle. I got off reta, ate a LOT (I'm carnivore) and put on 7-8 lbs of lean mass in ONE WEEK. Crazy.
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Thats interesting. So did it help or hinder weight loss? Retas stalled for my ts. Inquiring minds and all that. Haha also is there even a grey vendor for these? Seems like the lionsshare is gate kept by a bunch of american resellers with single syllable names like chip and rod.
Thats interesting. So did it help or hinder weight loss? Retas stalled for my ts. Inquiring minds and all that. Haha also is there even a grey vendor for these? Seems like the lionsshare is gate kept by a bunch of american resellers with single syllable names like chip and rod.
It is a VERY complicated construct. I would NOT even think of going outside (grey) the current ecosystem right now. WAY too risky from multiple aspects. Just buy it on sale with quantity discounts.
Consider your question! 'Weight loss" is not my goal and should NOT be your question. Body composition is. I'm up 17 lbs from bottom (155lbs), and now 12.5% body fat. So, fat way down, lean mass way up in 5 months. At age 65 what i did was "impossible" (lol)
You need to be quantifying your body composition. I use an InBody H30 with religiously repeated weighing parameters- AM, after toilet/sauna/resistance workout/shower. It must be identical regimen prior to every measure for repeatability. Absolute numbers not critical, but you get a clear TREND.
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@quicksilver80 Hi quick! So I would say that it helped weight loss- leaned me out in a way that was different from just losing fat. Before starting FLGR I had lost 20lbs with Reta at a dose of 0.5mg every 6 days. Probably never even benefitted from the glucagon effect with that low dose! But being a hyper-responder has its benefits? When visible changes stalled and the scale wouldn't budge I began to consider Reta might be holding me back from some of the follistatin benefits- you need calories to build muscle. It was time to cycle off reta anyway. The last 5 weeks I've added 4ish lbs which appears to be essentially all muscle. Can't prove it yet as next Dexa isn't until the fall.
You are correct about the supply chain/ gatekeeping. As I can tell you already know, Follistatin has been known and tried for decades. My understanding is that the patent is on the albumin binder, which extends the half-life to something like 2 weeks, not the follistatin itself. Hence unlikely to be found in the wild for a while. Rejoice in economies of scale though- down $300 for a months supply on BioLongevity Labs due to more efficient production! Hope that helps.@quicksilver80 Hi quick! So I would say that it helped weight loss- leaned me out in a way that was different from just losing fat. Before starting FLGR I had lost 20lbs with Reta at a dose of 0.5mg every 6 days. Probably never even benefitted from the glucagon effect with that low dose! But being a hyper-responder has its benefits? When visible changes stalled and the scale wouldn't budge I began to consider Reta might be holding me back from some of the follistatin benefits- you need calories to build muscle. It was time to cycle off reta anyway. The last 5 weeks I've added 4ish lbs which appears to be essentially all muscle. Can't prove it yet as next Dexa isn't until the fall.
You are correct about the supply chain/ gatekeeping. As I can tell you already know, Follistatin has been known and tried for decades. My understanding is that the patent is on the albumin binder, which extends the half-life to something like 2 weeks, not the follistatin itself. Hence unlikely to be found in the wild for a while. Rejoice in economies of scale though- down $300 for a months supply on BioLongevity Labs due to more efficient production! Hope that helps.YES, agreed with all. Well said. My experience as well.
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Yeah someone's needs to put a foot in the grey markets ass so normal mortals can get kits. Been thinking the synergy between growth and this would be interesting once you get past the water retention. Seeing how epicatechin works in the mean time.
Been thinking the synergy between growth and this would be interesting once you get past the water retention. .
Researching this now
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"Consider your question! 'Weight loss" is not my goal and should NOT be your question. Body composition is. I'm up 17 lbs from bottom (155lbs), and now 12.5% body fat. So, fat way down, lean mass way up in 5 months. At age 65 what i did was "impossible" (lol)"
^isnt this the end goal of weight loss in a mens context? Recomposition is still losing. Gaining 8 pounds of lean mass will end up raising your bmr and in turn your body will eat more calories and then shred more fat just sitting still? I mean i think any man alive would take that deal. In a WEEK? thats damn near short of a comic book character super serum. Like props man thats mind blowing. (I dont know why pc doesnt allow me to quote or reply directly to comments so...)
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"Consider your question! 'Weight loss" is not my goal and should NOT be your question. Body composition is. I'm up 17 lbs from bottom (155lbs), and now 12.5% body fat. So, fat way down, lean mass way up in 5 months. At age 65 what i did was "impossible" (lol)"
^isnt this the end goal of weight loss in a mens context? Recomposition is still losing. Gaining 8 pounds of lean mass will end up raising your bmr and in turn your body will eat more calories and then shred more fat just sitting still? I mean i think any man alive would take that deal. In a WEEK? thats damn near short of a comic book character super serum. Like props man thats mind blowing. (I dont know why pc doesnt allow me to quote or reply directly to comments so...)
@quicksilver80 YES. Recomp is elusive and the holy grail for me. I'm not a body builder, and I'm 5 years younger than Pete, but I always found bulking way easier than cutting- man I loved anything chocolate at about 7pm! That's why I'd characterize reta as tied for first as the GOAT- it helped me save me from myself! However, as muscle fat was also burning off, I honestly felt I looked a little wimpy, and all this while moderately lifting 6 days a week. FLGR242 comes along and it's essentially impossible to verify- it's all testimonial and honestly sounds too good to be true. Pete doesn't know it but his comments (starting in Dec and subsequent) felt to me like an independent voice validating the compounds promise and was a big factor in my decision to pull the trigger on what was a very large investment. Great call as long as my heart doesn't explode someday! Now I'm not running the mgs he is- at least I haven't yet- but I am tempted. The other thing tied for GOAT status in my book is FLGR. (I am not paid by Jay Campbell or anyone else to say this! LOL).
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@quicksilver80 YES. Recomp is elusive and the holy grail for me. I'm not a body builder, and I'm 5 years younger than Pete, but I always found bulking way easier than cutting- man I loved anything chocolate at about 7pm! That's why I'd characterize reta as tied for first as the GOAT- it helped me save me from myself! However, as muscle fat was also burning off, I honestly felt I looked a little wimpy, and all this while moderately lifting 6 days a week. FLGR242 comes along and it's essentially impossible to verify- it's all testimonial and honestly sounds too good to be true. Pete doesn't know it but his comments (starting in Dec and subsequent) felt to me like an independent voice validating the compounds promise and was a big factor in my decision to pull the trigger on what was a very large investment. Great call as long as my heart doesn't explode someday! Now I'm not running the mgs he is- at least I haven't yet- but I am tempted. The other thing tied for GOAT status in my book is FLGR. (I am not paid by Jay Campbell or anyone else to say this! LOL).
@Stones67 any weird side effects worth note? I feel like they'd be similar to gh
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Zero sides! But I'm also doing CJC/Ipa 5 nights a week. Funny you should mention gh. Been considering a trail of that to see how much difference there is- you know for s&g's! But I'm still in the headspace of seeing how much I can push my own biology to make the good stuff before reaching for the nectar itself!
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@Stones67 any weird side effects worth note? I feel like they'd be similar to gh
@quicksilver80 sorry. Forgot to hit reply. See above. Or below. Wherever! You'll see it! trial not trail.
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@quicksilver80 sorry. Forgot to hit reply. See above. Or below. Wherever! You'll see it! trial not trail.
@Stones67 @peptidepete @diegoc Following the thread on Biolongevity Labs. Are you gentlemen still researching with this? And are your results still trending in the right direction?
I saw Josh Holyfield just released a video on YT today that wasn’t necessarily positive. Obviously one needs to take the opinion of a market competitor with a grain of salt. I know each of you are pretty active in this space and I view your anecdotal research as legitimate information.
I’ve been waiting on a sale to make this purchase. It is substantial for me, but worth it if it works as intended. TIA
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@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
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As noted in previous threads I have been on it continually since it was introduced to the market at the end of december. The past several months have been 1 mg per day . Every day. No breaks. I was just thinking the other day I feel like I've probably topped out or maxed out or whatever you want to call it. If you want to look at the research and the charts on the Bimagrumab and if your research leads you to believe that the results for flgr242 can and should be similar, then I'm now entering the time period where that would occur. It makes sense to me that the majority of gains would occur early in the use of the material. As I recall the second and third month or the massive growth phases where I just wanted to work out every day. With all that said I remain of the opinion that I will be on this until some other kind of myostatin inhibitor that is better comes down the line. My lean mass gains and fat loss are inarguable, and at my age the muscle gain by conventional wisdom is not possible. Now I don't know who this Josh guy is and I don't trust anybody all I trust is my own research because everybody is conflicted. So I would urge anyone to do their own research and make their own determination and I think the facts of the matter will become crystal clear to them. If I've not already said this, results don't occur overnight they don't occur within a week and they only start to occur within a month I think anyone who is serious about researching this material should not do so unless they have every intention to do it for 3 months straight. So there's some food for for you
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@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
Klotho is very subtle. I believe I noticed it, I believe it had and has noticeable benefits, and I believe like flgr242 it's something that you need to plan on using until something better comes along and that may be years from now . It's not a one hit wonder, it's not you do one or two vials and then you're one and done . If you're older and you're deficient that's just the fact of the matter and you're going to be using it until the day you die or something else comes along . That's my personal opinion of course but it's also backed up by science in regards to age deficiency. It's anecdotal and not 100% direct but I do have frequent Labs run, kidney function is perfect and I do some other materials that are somewhat stressful on the physiology
so that's somewhat of a objective measure. I also use cystatin C as my testing not the usual egfr which if you're using creatine at higher levels as I am can affect regular egFR. So be a careful and smart researcher. Bottom line I'm still on it and I plan to be on it as I said , it's not something that you want to cycle it makes no sense to do so. Hope that helps -
@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
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@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.
Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked
that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it 
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@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.
Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it @PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
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@PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
@PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
My n = 1 and diligent and deep regular testing is all the information I need. Thanks for the additional info on the video I may actually have this guy blocked on youtube, I'll have to look him up and watch it and see what he has to say. I have nothing to sell to anybody except for truth and the strongest possible suggestion that anyone form their opinions based on nothing other than their own research. It seems like everything except for the tiniest percent is nothing more than propaganda or a psyop
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I'm another N=1. I'm 59yo. I'm exactly at 3 months since starting FLGR (no Klotho) and without a doubt have recorded visible changes in my physique that would not have occurred without running gear. Labs done after a month were all improved (fasted glucose, A1c, etc) but at the time was also running reta at 0.5mg every 6 days. Next labs in about a month and I may not be able to stop myself from adding a repeat Dexa (my curiosity is getting the better of me). I believe it (flgr) is allowing me to move beyond my myostatin regulated genetic potential. My testosterone is optimized with enclomiphene and I enjoy CJC/Ipa. The grey hair not withstanding, I look and feel closer to 40. But this is a speculative play. Not in terms of results, as I can honestly vouch for those now, but in terms of safety. I have enough stocked away for another year but am considering running this for another 3 months or so, and then taking a few months off. I'm honestly curious about the durability of results. I think Pete will still be on the stuff when he croaks at 150! Only buy when on sale (I don't buy anything else on BLL cuz all their stuff is crazy expensive) but shoot for at least 6 months. I wouldn't be surprised if they do something enticing over the 4th. Someone else is going to eventually reverse engineer the albumin binder part or figure out another way to extend half-life. The monoclonal antibody stuff is intriguing and I'll take my cues from quicksilver as he formulates his thoughts over time. Or go to Panama or the Bahamas or wherever and have your genes altered! Otherwise it's PED's or FLGR as far as I can tell! I watch Josh H. and think he does OK making AI research sound like his own. Unfortunately there is no real research on this new stuff so unless he tries it for 6 months he really doesn't know anything. Hope that helps and happy to chime in anytime!
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