@mitchelldemeter OK, maybe you can answer me this LC-MS question. For example, during synthesis of EDR they messed up and made it in reverse: RDE. Will it be detected or we will think it's EDR because the mass is the same?
Or, in a longer peptide chain, if 2 amino acids are swapped because of operator error. Sometimes it is possible, as I understand. The total number of amino acids in the chain will be the same, just the order is different. Can it be detected?