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Klotho / FLGR242 (albumin-bound new tech)

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586 Posts 41 Posters 62.9k Views 9 Watching
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  • MacLeeezyM MacLeeezy

    4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or isflex.jpg a top tier placebo. Either way I’m happy thus far

    D Online
    D Online
    denti
    wrote last edited by
    #548

    @MacLeeezy said:

    4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is the a top tier placebo. Either way I’m happy thus far

    I am also taking enclomiphine but 12.5mg 3x a week and 1 vial of slim assist (2mg FLGR) weekly. It's been 6 weeks for me. Did you titrate up to 2 vials of slim assist or did you just start off at 2 vials? I'm thinking of moving up on it but wondering if I should do 2 vials at once or split it between the week. Interested in hearing your protocol as we seem to be on the same thing.

    1 Reply Last reply
    1
    • MacLeeezyM Offline
      MacLeeezyM Offline
      MacLeeezy
      wrote last edited by
      #549

      i started at a single vial for 2 weeks. and then went up to two vials. im told that i probably titrated up too fast but now that im here i should hold for 90 days before going any further.

      1 Reply Last reply
      2
      • ImaFrogNotaRatI Offline
        ImaFrogNotaRatI Offline
        ImaFrogNotaRat
        wrote last edited by ImaFrogNotaRat
        #550

        Yesterday, JC hosted Mike Farber again who basically answered questions about Alpha-Klotho, FLGR-242, and BioLean, which will soon be available. He also mentioned the drop in price for the signature peptides. I do have the Jamie AI Executive Summary of the talk.

        FLGR-242 Klotho Farber Jay.pdf

        The epigenome is malleable. Squish responsibly.

        1 Reply Last reply
        2
        • D Online
          D Online
          denti
          wrote last edited by
          #551

          I wish I bought more of Slim Assist in that deal a little while back. This pricing of 299/2 vials of FLGR242 is way too expensive in comparison to slim assist which came out to $17 a vial for me.

          ImaFrogNotaRatI vpepsV 2 Replies Last reply
          2
          • D denti

            I wish I bought more of Slim Assist in that deal a little while back. This pricing of 299/2 vials of FLGR242 is way too expensive in comparison to slim assist which came out to $17 a vial for me.

            ImaFrogNotaRatI Offline
            ImaFrogNotaRatI Offline
            ImaFrogNotaRat
            wrote last edited by
            #552

            @denti I imagine there may be a holiday special coming up. 'tis the season to be scared and thankful?! 🎃 👹 🌽 🎄

            The epigenome is malleable. Squish responsibly.

            1 Reply Last reply
            3
            • Mr SmurfM Online
              Mr SmurfM Online
              Mr Smurf
              wrote last edited by
              #553

              20260927_150704.jpg
              Stuffs pretty rad

              P 1 Reply Last reply
              4
              • D denti

                I wish I bought more of Slim Assist in that deal a little while back. This pricing of 299/2 vials of FLGR242 is way too expensive in comparison to slim assist which came out to $17 a vial for me.

                vpepsV Offline
                vpepsV Offline
                vpeps
                wrote last edited by
                #554

                @denti Slim Assist is still available.

                attentiion is all you need

                D 2 Replies Last reply
                0
                • vpepsV vpeps

                  @denti Slim Assist is still available.

                  D Online
                  D Online
                  denti
                  wrote last edited by denti
                  #555

                  @vpeps said:

                  @denti Slim Assist is still available.

                  Really? Link me please.

                  Edit: Sorry I am dumb. I see you did link me. Thank you.

                  Edit 2: This comes out to about $32 a vial vs the $17 a couple months back. I think couple months ago it was on sale an then the jayc code on top to drop the price to $17 a vial.

                  vpepsV 1 Reply Last reply
                  2
                  • T Offline
                    T Offline
                    The Spatalian
                    wrote last edited by
                    #556

                    Been on FLGR for 15 weeks. Started at 2.5mg. After zero change. I upped to 5 the last 4 weeks. Have put on a few pounds of muscle. And FAT. But keep in mind. According to the manufacturer. You have to up your calories 50-75% above BMR. REALLY hard to do. I maintain my 170-200 grams of protein.
                    Here's what Ive taken into account. I increased the intensity of strength training. Just because I don't want that to be a reason I'm not seeing gains. My Sleep averages 7.5 hours of quality sleep. I eliminated all other peptides. Just to not affect results.
                    I'm 68. 180# 14% body fat (Dexa every month) been strength training for 50+ years. Retired from the fitness industry. Very disciplined.
                    My take? Not worth the price. More hype than science (which there is none of) and think I should have gone a HG peptides route or just HGH. Do need to mention I've been on TRT for 8 years and maintain excellent blood markers across the board. Maybe I'm just a non responder?
                    Good on all of those who claim huge increases in muscle mass after a couple of months. But...until I see MRI scans proving that. Or really know what's in the vials? I'll not continue FLGR-242

                    P 1 Reply Last reply
                    1
                    • P PeptidePete

                      Quick follow-up on the new Kimera Chems Na Salt-form O-304. It's potent, I'm quite fine on 50-100mg of it vs 400-600mg of the free-acid versions being sold by EVERYONE else. Homework is your friend, once again.

                      The 5-Amino-1MQ 50mg tabs from QSC are great, one less ting I have to pin and far more cost effective (cost per mg). No negs that I can discern.

                      Again do your homework. For those who enjoy him, Nick Norwitz has some thought-provoking papers on both. Check his Substack.

                      I'd suggest both of these are oriented towards those looking to fine-tune what is already a well optimized regimen and body.

                      My research with SS-31 at 60mg per day, every day, remains ongoing.

                      T Offline
                      T Offline
                      The Spatalian
                      wrote last edited by
                      #557

                      @PeptidePete what's your monthly cost for SS-31 @ that dose? Must be a luxury car payment!

                      1 Reply Last reply
                      0
                      • D denti

                        @vpeps said:

                        @denti Slim Assist is still available.

                        Really? Link me please.

                        Edit: Sorry I am dumb. I see you did link me. Thank you.

                        Edit 2: This comes out to about $32 a vial vs the $17 a couple months back. I think couple months ago it was on sale an then the jayc code on top to drop the price to $17 a vial.

                        vpepsV Offline
                        vpepsV Offline
                        vpeps
                        wrote last edited by
                        #558

                        @denti yes, they had one of their 50% off sales. I am sure they will have another one in the future. But they still keep that "buy 10 get 15 free" going for SlimAssist.

                        attentiion is all you need

                        1 Reply Last reply
                        2
                        • MacLeeezyM Offline
                          MacLeeezyM Offline
                          MacLeeezy
                          wrote last edited by
                          #559

                          Yep seems like the real deal is wait for the next big sale and buy 20 slim assists on a discount and get another 30 for free, for hopefully around that $17 price point again. I definitely took advantage of that last time as well.

                          1 Reply Last reply
                          2
                          • D Online
                            D Online
                            denti
                            wrote last edited by
                            #560

                            If that 50% deal comes up again please post it here. I have not been getting emails from them so I do not want to miss out on the next sale Thanks.

                            1 Reply Last reply
                            1
                            • MacLeeezyM MacLeeezy

                              4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or isflex.jpg a top tier placebo. Either way I’m happy thus far

                              P Offline
                              P Offline
                              PeptidePete
                              wrote last edited by
                              #561

                              @MacLeeezy said:

                              4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or isflex.jpg a top tier placebo. Either way I’m happy thus far

                              Wow! And....exactly what I would expect 🙂

                              Please update after more weeks. Based on my experience you have 3-4 great months ahead of you.

                              1 Reply Last reply
                              1
                              • Mr SmurfM Mr Smurf

                                20260927_150704.jpg
                                Stuffs pretty rad

                                P Offline
                                P Offline
                                PeptidePete
                                wrote last edited by
                                #562

                                @Mr-Smurf said:

                                20260927_150704.jpg
                                Stuffs pretty rad

                                WOW! Vascularity and definition, exactly what I experienced. Please keep us updated?

                                1 Reply Last reply
                                0
                                • T The Spatalian

                                  Been on FLGR for 15 weeks. Started at 2.5mg. After zero change. I upped to 5 the last 4 weeks. Have put on a few pounds of muscle. And FAT. But keep in mind. According to the manufacturer. You have to up your calories 50-75% above BMR. REALLY hard to do. I maintain my 170-200 grams of protein.
                                  Here's what Ive taken into account. I increased the intensity of strength training. Just because I don't want that to be a reason I'm not seeing gains. My Sleep averages 7.5 hours of quality sleep. I eliminated all other peptides. Just to not affect results.
                                  I'm 68. 180# 14% body fat (Dexa every month) been strength training for 50+ years. Retired from the fitness industry. Very disciplined.
                                  My take? Not worth the price. More hype than science (which there is none of) and think I should have gone a HG peptides route or just HGH. Do need to mention I've been on TRT for 8 years and maintain excellent blood markers across the board. Maybe I'm just a non responder?
                                  Good on all of those who claim huge increases in muscle mass after a couple of months. But...until I see MRI scans proving that. Or really know what's in the vials? I'll not continue FLGR-242

                                  P Offline
                                  P Offline
                                  PeptidePete
                                  wrote last edited by
                                  #563

                                  @The-Spatalian said:

                                  Been on FLGR for 15 weeks. Started at 2.5mg. After zero change. I upped to 5 the last 4 weeks. Have put on a few pounds of muscle. And FAT. But keep in mind. According to the manufacturer. You have to up your calories 50-75% above BMR. REALLY hard to do. I maintain my 170-200
                                  Good on all of those who claim huge increases in muscle mass after a couple of months. But...until I see MRI scans proving that. Or really know what's in the vials? I'll not continue FLGR-242

                                  Interesting data point, thanks for posting!

                                  1 Reply Last reply
                                  0
                                  • P Offline
                                    P Offline
                                    PeptidePete
                                    wrote last edited by PeptidePete
                                    #564

                                    Update:

                                    New labs look great Cystatin C 1.11->1.04, Iron/TBIC/Ferritin finally all within optimum range. Stamina ever increasing (fixed ferritin).

                                    Completed SS-31 2 month 50mg daily run, surprising effect on urine flow increase. Wonder if synergistic in combo with the Klotho? Could be/Should be when you think it. The cost of SS-31, first off I loaded up from multiple vendors who were blowing out stocks Dec-Feb in fear, second, QSC offers 50mg at .70/mg. Understand screaming deals when you see them, then, act on them. In regards to expense, what I look at is value, what else is proven to do what elamipretide does? Nothing. I plan to run another two month course in a couple months from now, so 2 on, then 3 off, rinse repeat.

                                    BTW- the proven minimum efficacious dose is what it is, I've seen zero evidence anything less than 40mg daily is effective, indeed the opposite. The molecule doesn't care if anyone likes that or not.

                                    Ran an experiment stopping variable-resistance training for two months to observe effect on Skeletal Muscle Mass, shock, only dropped 1lb. There is another benefit I attribute to FLGR. Maintain the gain if you go on vacation for a couple months 🙂

                                    vpepsV 1 Reply Last reply
                                    3
                                    • P PeptidePete

                                      Update:

                                      New labs look great Cystatin C 1.11->1.04, Iron/TBIC/Ferritin finally all within optimum range. Stamina ever increasing (fixed ferritin).

                                      Completed SS-31 2 month 50mg daily run, surprising effect on urine flow increase. Wonder if synergistic in combo with the Klotho? Could be/Should be when you think it. The cost of SS-31, first off I loaded up from multiple vendors who were blowing out stocks Dec-Feb in fear, second, QSC offers 50mg at .70/mg. Understand screaming deals when you see them, then, act on them. In regards to expense, what I look at is value, what else is proven to do what elamipretide does? Nothing. I plan to run another two month course in a couple months from now, so 2 on, then 3 off, rinse repeat.

                                      BTW- the proven minimum efficacious dose is what it is, I've seen zero evidence anything less than 40mg daily is effective, indeed the opposite. The molecule doesn't care if anyone likes that or not.

                                      Ran an experiment stopping variable-resistance training for two months to observe effect on Skeletal Muscle Mass, shock, only dropped 1lb. There is another benefit I attribute to FLGR. Maintain the gain if you go on vacation for a couple months 🙂

                                      vpepsV Offline
                                      vpepsV Offline
                                      vpeps
                                      wrote last edited by
                                      #565

                                      @PeptidePete said:

                                      Iron/TBIC/Ferritin finally all within optimum range

                                      What do you consider as optimal values for these?

                                      attentiion is all you need

                                      P 1 Reply Last reply
                                      0
                                      • MacLeeezyM Offline
                                        MacLeeezyM Offline
                                        MacLeeezy
                                        wrote last edited by
                                        #566

                                        Just got an email from biolongevity that said once they sell out of their remaining 700 vials, “slim assist” will be NO more…

                                        D quicksilver80Q 2 Replies Last reply
                                        1
                                        • ResearchCatR Offline
                                          ResearchCatR Offline
                                          ResearchCat
                                          wrote last edited by
                                          #567

                                          Yeah, but they said that in the last sale, too.

                                          Yeah, well, I’m just here for the research, man. - The Dude

                                          If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                                          1 Reply Last reply
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